PMID- 27895998
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200930
IS  - 2156-7085 (Print)
IS  - 2156-7085 (Electronic)
IS  - 2156-7085 (Linking)
VI  - 7
IP  - 11
DP  - 2016 Nov 1
TI  - Quantifying intraocular scatter with near diffraction-limited double-pass point 
      spread function.
PG  - 4595-4604
AB  - Measurement of the double-pass (DP) point-spread function (PSF) can provide an 
      objective and non-invasive method for estimating intraocular scatter in the human 
      eye. The objective scatter index (OSI), which is calculated from the DP PSF 
      images, is commonly used to quantify intraocular scatter. In this article, we 
      simulated the effect of higher-order ocular aberrations on OSI, and the results 
      showed that higher-order ocular aberrations had a significant influence on OSI. 
      Then we developed an adaptive optics DP PSF measurement system (AO-DPPMS) which 
      was capable of correcting ocular aberrations up to eighth-order radial Zernike 
      modes over a 6.0-mm pupil. Employing this system, we obtained DP PSF images of 
      four subjects at the fovea. OSI values with aberrations corrected up to 2nd, 5th 
      and 8th Zernike order were calculated respectively, from the DP PSF images of the 
      four subjects. The experimental results were consistent with the simulation, 
      suggesting that it is necessary to compensate for the higher-order ocular 
      aberrations for accurate intraocular scatter estimation.
FAU - Zhao, Junlei
AU  - Zhao J
AD  - The Key Laboratory on Adaptive Optics, Chinese Academy of Sciences, Chengdu 
      610209, China; The Laboratory on Adaptive Optics, Institute of Optics and 
      Electronics, Chinese Academy of Sciences, Chengdu 610209, China; University of 
      Chinese Academy of Sciences, Beijing 100049, China.
FAU - Xiao, Fei
AU  - Xiao F
AD  - The Key Laboratory on Adaptive Optics, Chinese Academy of Sciences, Chengdu 
      610209, China; The Laboratory on Adaptive Optics, Institute of Optics and 
      Electronics, Chinese Academy of Sciences, Chengdu 610209, China.
FAU - Kang, Jian
AU  - Kang J
AD  - The Key Laboratory on Adaptive Optics, Chinese Academy of Sciences, Chengdu 
      610209, China; The Laboratory on Adaptive Optics, Institute of Optics and 
      Electronics, Chinese Academy of Sciences, Chengdu 610209, China; University of 
      Chinese Academy of Sciences, Beijing 100049, China.
FAU - Zhao, Haoxin
AU  - Zhao H
AD  - The Key Laboratory on Adaptive Optics, Chinese Academy of Sciences, Chengdu 
      610209, China; The Laboratory on Adaptive Optics, Institute of Optics and 
      Electronics, Chinese Academy of Sciences, Chengdu 610209, China.
FAU - Dai, Yun
AU  - Dai Y
AD  - The Key Laboratory on Adaptive Optics, Chinese Academy of Sciences, Chengdu 
      610209, China; The Laboratory on Adaptive Optics, Institute of Optics and 
      Electronics, Chinese Academy of Sciences, Chengdu 610209, China; 
      daiyunqq@163.com.
FAU - Zhang, Yudong
AU  - Zhang Y
AD  - The Key Laboratory on Adaptive Optics, Chinese Academy of Sciences, Chengdu 
      610209, China; The Laboratory on Adaptive Optics, Institute of Optics and 
      Electronics, Chinese Academy of Sciences, Chengdu 610209, China; 
      ydzhang@ioe.ac.cn.
LA  - eng
PT  - Journal Article
DEP - 20161017
PL  - United States
TA  - Biomed Opt Express
JT  - Biomedical optics express
JID - 101540630
PMC - PMC5119598
OTO - NOTNLM
OT  - (110.1080) Active or adaptive optics
OT  - (170.0110) Imaging systems
OT  - (170.4460) Ophthalmic optics and devices
EDAT- 2016/11/30 06:00
MHDA- 2016/11/30 06:01
PMCR- 2016/10/17
CRDT- 2016/11/30 06:00
PHST- 2016/08/15 00:00 [received]
PHST- 2016/10/04 00:00 [revised]
PHST- 2016/10/06 00:00 [accepted]
PHST- 2016/11/30 06:00 [entrez]
PHST- 2016/11/30 06:00 [pubmed]
PHST- 2016/11/30 06:01 [medline]
PHST- 2016/10/17 00:00 [pmc-release]
AID - 273899 [pii]
AID - 10.1364/BOE.7.004595 [doi]
PST - epublish
SO  - Biomed Opt Express. 2016 Oct 17;7(11):4595-4604. doi: 10.1364/BOE.7.004595. 
      eCollection 2016 Nov 1.