PMID- 27900767
OWN - NLM
STAT- MEDLINE
DCOM- 20170309
LR  - 20170817
IS  - 1399-6576 (Electronic)
IS  - 0001-5172 (Linking)
VI  - 61
IP  - 2
DP  - 2017 Feb
TI  - Cumulative changes in weight but not fluid volume balances reflect fluid 
      accumulation in ICU patients.
PG  - 205-215
LID - 10.1111/aas.12840 [doi]
AB  - BACKGROUND: The cumulative fluid balance of critically ill patients seems to be 
      an outcome-relevant variable. However, there are no validated data for their 
      reliability calculated for longer (> 5 days) periods of time. METHODS: All ICU 
      patients >/= 18 years, with an ICU stay >/= 5 days and a body weight </= 195 kg were 
      evaluated from 1 January 2013 to 31 December 2013. Daily standardized weighing 
      was performed using bed-integrated scales simultaneously with the daily 24-h 
      fluid balance. Simultaneously, a fluid balance without and with insensible 
      perspiration (10 ml/kg/day) was calculated for each 24 h. Primary endpoint: 
      difference between cumulative fluid balance and body weight changes at the day of 
      transfer to the normal ward or the day of death in the ICU, respectively, in each 
      patient. All data are presented as medians with interquartile ranges (IQR) with 
      25 and 75 percentiles (IQR/25/75) unless otherwise noted. RESULTS: One hundred 
      and six critically ill patients were evaluated; 82 survivors and 24 nonsurvivors. 
      Cumulative 24-h fluid balances rose continuously while body weight decreased over 
      time. Correction of cumulative fluid balances for insensible perspiration (10 
      ml/kg/day) also did not match with body weight changes. Only survivors had a 
      significant loss in body weight -1.8 (27.5/-6.1/1.0) kg. CONCLUSIONS: Assuming 
      that changes in body weight reflect changes in whole body water content 
      cumulative daily fluid volume balances without or with correction for insensible 
      water loss are not useful for estimating cumulative fluid balance of ICU 
      patients. Survivors but not nonsurvivors had a significant loss of weight over 
      time.
CI  - (c) 2016 The Acta Anaesthesiologica Scandinavica Foundation. Published by John 
      Wiley & Sons Ltd.
FAU - Koster, M
AU  - Koster M
AD  - Department of Anaesthesia and Perioperative Medicine, Asklepios Klinik Langen, 
      Langen, Germany.
FAU - Dennhardt, S
AU  - Dennhardt S
AD  - Department of Anaesthesia and Perioperative Medicine, Asklepios Klinik Langen, 
      Langen, Germany.
FAU - Juttner, F
AU  - Juttner F
AD  - Department of Anaesthesia and Perioperative Medicine, Asklepios Klinik Langen, 
      Langen, Germany.
FAU - Hopf, H-B
AU  - Hopf HB
AD  - Department of Anaesthesia and Perioperative Medicine, Asklepios Klinik Langen, 
      Langen, Germany.
LA  - eng
PT  - Journal Article
DEP - 20161130
PL  - England
TA  - Acta Anaesthesiol Scand
JT  - Acta anaesthesiologica Scandinavica
JID - 0370270
SB  - IM
MH  - Aged
MH  - *Body Weight
MH  - Critical Illness
MH  - Female
MH  - Humans
MH  - *Intensive Care Units
MH  - Length of Stay
MH  - Male
MH  - Middle Aged
MH  - *Water-Electrolyte Balance
EDAT- 2016/12/03 06:00
MHDA- 2017/03/10 06:00
CRDT- 2016/12/01 06:00
PHST- 2016/04/24 00:00 [received]
PHST- 2016/09/19 00:00 [revised]
PHST- 2016/11/03 00:00 [accepted]
PHST- 2016/12/03 06:00 [pubmed]
PHST- 2017/03/10 06:00 [medline]
PHST- 2016/12/01 06:00 [entrez]
AID - 10.1111/aas.12840 [doi]
PST - ppublish
SO  - Acta Anaesthesiol Scand. 2017 Feb;61(2):205-215. doi: 10.1111/aas.12840. Epub 
      2016 Nov 30.