PMID- 27905214
OWN - NLM
STAT- MEDLINE
DCOM- 20170323
LR  - 20181202
IS  - 1502-7686 (Electronic)
IS  - 0036-5513 (Linking)
VI  - 77
IP  - 2
DP  - 2017 Apr
TI  - The association of plasma oxidative status and inflammation with the development 
      of atrial fibrillation in patients presenting with ST elevation myocardial 
      infarction.
PG  - 77-82
LID - 10.1080/00365513.2016.1244857 [doi]
AB  - Atrial fibrillation (AF) is the most common supraventricular arrhythmia following 
      ST elevation myocardial infarction (STEMI). Oxidative stress and inflammation may 
      cause structural and electrical remodeling in the atria making these critical 
      processes in the pathology of AF. In this study, we aimed to evaluate the 
      association between total oxidative status (TOS), total antioxidative capacity 
      (TAC) and high-sensitivity C-reactive protein (hs-CRP) in the development of AF 
      in patients presenting with STEMI. This prospective cohort study consisted of 346 
      patients with STEMI. Serum TAC and TOS were assessed by Erel's method. Patients 
      were divided into two groups: those with and those without AF. Predictors of AF 
      were determined by multivariate regression analysis. In the present study, 9.5% 
      of patients developed AF. In the patients with AF, plasma TOS and oxidative 
      stress index (OSI) values were significantly higher and plasma TAC levels were 
      significantly lower compared to those without AF (p = .003, p = .002, p < .0001, 
      respectively). Multivariate regression analysis results showed that, female 
      gender (Odds ratio [OR] = 3.07; 95% Confidence Interval [CI] = 1.26-7.47; 
      p = .01), left atrial diameter (OR =1.28; 95% CI =1.12-1.47; p < .0001), hs-CRP 
      (OR =1.02; 95% CI =1.00-1.03; p = .001) and OSI (OR =1.10; 95% CI =1.04-1.18; 
      p = .001) were associated with the development of AF in patients presenting with 
      STEMI. The main finding of this study is that oxidative stress and inflammation 
      parameters were associated with the development of AF in patients presenting with 
      STEMI. Other independent predictors of AF were female gender, left atrial 
      diameter and hs-CRP.
FAU - Bas, Hasan Aydin
AU  - Bas HA
AD  - a Department of Cardiology , Isparta State Hospital , Isparta , Turkey.
FAU - Aksoy, Fatih
AU  - Aksoy F
AD  - b Department of Cardiology , Dinar state Hospital , Afyonkarahisar , Turkey.
FAU - Icli, Atilla
AU  - Icli A
AD  - c Department of Cardiology , Ahi Evran University , Kirsehir , Turkey.
FAU - Varol, Ercan
AU  - Varol E
AD  - d Department of Cardiology , Suleyman Demirel University School of Medicine , 
      Isparta , Turkey.
FAU - Dogan, Abdullah
AU  - Dogan A
AD  - d Department of Cardiology , Suleyman Demirel University School of Medicine , 
      Isparta , Turkey.
FAU - Erdogan, Dogan
AU  - Erdogan D
AD  - d Department of Cardiology , Suleyman Demirel University School of Medicine , 
      Isparta , Turkey.
FAU - Ersoy, Ibrahim
AU  - Ersoy I
AD  - a Department of Cardiology , Isparta State Hospital , Isparta , Turkey.
FAU - Arslan, Akif
AU  - Arslan A
AD  - d Department of Cardiology , Suleyman Demirel University School of Medicine , 
      Isparta , Turkey.
FAU - Ari, Hatem
AU  - Ari H
AD  - d Department of Cardiology , Suleyman Demirel University School of Medicine , 
      Isparta , Turkey.
FAU - Bas, Nihal
AU  - Bas N
AD  - e Internal Medicine , Isparta State Hospital , Isparta , Turkey.
FAU - Sutcu, Recep
AU  - Sutcu R
AD  - f Department of Clinical Chemistry , Izmir Katip Celebi University School of 
      Medicine , Izmir , Turkey.
FAU - Ozaydin, Mehmet
AU  - Ozaydin M
AD  - d Department of Cardiology , Suleyman Demirel University School of Medicine , 
      Isparta , Turkey.
LA  - eng
PT  - Journal Article
DEP - 20161201
PL  - England
TA  - Scand J Clin Lab Invest
JT  - Scandinavian journal of clinical and laboratory investigation
JID - 0404375
RN  - 0 (Biomarkers)
RN  - 9007-41-4 (C-Reactive Protein)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Atrial Fibrillation/*blood/diagnosis/etiology/pathology
MH  - Biomarkers/blood
MH  - C-Reactive Protein/*metabolism
MH  - Female
MH  - Heart Atria/metabolism/*pathology
MH  - Humans
MH  - Inflammation
MH  - Male
MH  - Middle Aged
MH  - Myocardium/metabolism/*pathology
MH  - Odds Ratio
MH  - Oxidative Stress
MH  - Prospective Studies
MH  - Regression Analysis
MH  - Risk Factors
MH  - ST Elevation Myocardial Infarction/*blood/complications/diagnosis/pathology
MH  - Sex Factors
OTO - NOTNLM
OT  - Antioxidants
OT  - atrial fibrillation
OT  - inflammation
OT  - myocardial infarction
OT  - oxidative stress
EDAT- 2016/12/03 06:00
MHDA- 2017/03/24 06:00
CRDT- 2016/12/02 06:00
PHST- 2016/12/03 06:00 [pubmed]
PHST- 2017/03/24 06:00 [medline]
PHST- 2016/12/02 06:00 [entrez]
AID - 10.1080/00365513.2016.1244857 [doi]
PST - ppublish
SO  - Scand J Clin Lab Invest. 2017 Apr;77(2):77-82. doi: 
      10.1080/00365513.2016.1244857. Epub 2016 Dec 1.