PMID- 27910746
OWN - NLM
STAT- MEDLINE
DCOM- 20170907
LR  - 20180529
IS  - 1045-4403 (Print)
IS  - 1045-4403 (Linking)
VI  - 26
IP  - 4
DP  - 2016
TI  - Nutrition and Diabetes Mellitus: How are They Interlinked?
PG  - 317-332
AB  - The prevalence of type 2 diabetes mellitus (T2DM) has risen exponentially, and 
      the number of incidences increases every day. The purpose of this article is to 
      summarize the experimental evidence supporting the important association between 
      nutrition and diet-based therapy for the control and management of T2DM. Evidence 
      from several in vitro, in vivo, and human studies broadly found that 
      nutrition-based therapy enriched with several important phytochemical 
      constituents modulates lipid and carbohydrate metabolism, and it ameliorates 
      glucolipotoxicity and insulin resistance. Besides these activities, 
      nutrition-based therapy has also been shown to improve adipose tissue metabolism 
      and to alleviate various proinflammatory processes, oxidative stress, and 
      stress-sensitive signaling pathways. Dietary recommendations for patients with 
      type 2 diabetes emphasize diet-based therapy and include excellent sources of 
      dietary fibers and polyphenols.
FAU - Rehman, Kanwal
AU  - Rehman K
AD  - Institute of Pharmacy, Physiology and Pharmacology, University of Agriculture, 
      Faisalabad, Pakistan.
FAU - Akash, Muhammad Sajid Hamid
AU  - Akash MS
AD  - Department of Pharmaceutical Chemistry, Government College University Faisalabad, 
      Pakistan.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Crit Rev Eukaryot Gene Expr
JT  - Critical reviews in eukaryotic gene expression
JID - 9007261
RN  - 0 (Dietary Fiber)
RN  - 0 (Polyphenols)
SB  - IM
MH  - Adipose Tissue/metabolism
MH  - Diabetes Mellitus, Type 2/*diet therapy
MH  - *Diet, Diabetic
MH  - Dietary Fiber
MH  - Female
MH  - Humans
MH  - Male
MH  - Oxidative Stress
MH  - Polyphenols
MH  - Recommended Dietary Allowances
MH  - Signal Transduction
EDAT- 2016/12/03 06:00
MHDA- 2017/09/08 06:00
CRDT- 2016/12/03 06:00
PHST- 2016/12/03 06:00 [entrez]
PHST- 2016/12/03 06:00 [pubmed]
PHST- 2017/09/08 06:00 [medline]
AID - 73c57fd25a6798d9,794007d912ae6333 [pii]
AID - 10.1615/CritRevEukaryotGeneExpr.2016016782 [doi]
PST - ppublish
SO  - Crit Rev Eukaryot Gene Expr. 2016;26(4):317-332. doi: 
      10.1615/CritRevEukaryotGeneExpr.2016016782.