PMID- 27919159
OWN - NLM
STAT- MEDLINE
DCOM- 20170824
LR  - 20181113
IS  - 2005-6648 (Electronic)
IS  - 1226-3303 (Print)
IS  - 1226-3303 (Linking)
VI  - 32
IP  - 2
DP  - 2017 Mar
TI  - Atrial conduction times and left atrial mechanical functions and their relation 
      with diastolic function in prediabetic patients.
PG  - 286-294
LID - 10.3904/kjim.2014.380 [doi]
AB  - BACKGROUND/AIMS: The aim of this study was to investigate atrial conduction times 
      and left atrial mechanical functions, the noninvasive predictors of atrial 
      fibrillation, in prediabetic patients with impaired fasting glucose (IFG) and 
      impaired glucose tolerance (IGT). METHODS: Study included 59 patients (23 males, 
      36 females; mean age 52.5 +/- 10.6 years) diagnosed with IFG or IGT by the American 
      Diabetes Association criteria, and 43 healthy adults (22 males, 21 females; mean 
      age 48.5 +/- 12.1 years). Conventional and tissue Doppler echocardiography were 
      performed. The electromechanical delay parameters were measured from the onset of 
      the P wave on the surface electrocardiogram to the onset of the atrial systolic 
      wave on tissue Doppler imaging from septum, lateral, and right ventricular 
      annuli. The left atrial volumes were calculated by the disk method. Left atrial 
      mechanical functions were calculated. RESULTS: The mitral E/A and E'/A' ratios 
      measured from the lateral and septal annuli were significantly lower in the 
      prediabetics compared to the controls. The interatrial and left atrial 
      electromechanical delay were significantly longer in prediabetic group compared 
      to the controls. Left atrial active emptying volume (LAAEV) and fraction (LAAEF) 
      were significantly higher in the prediabetics than the controls. LAAEV and LAAEF 
      were significantly correlated with E/A, lateral and septal E'/A'. CONCLUSIONS: In 
      the prediabetic patients, the atrial conduction times and P wave dispersion on 
      surface electrocardiographic were longer before the development of overt 
      diabetes. In addition, the left atrial mechanical functions were impaired 
      secondary to a deterioration in the diastolic functions in the prediabetic 
      patients.
FAU - Gudul, Naile Eris
AU  - Gudul NE
AD  - Department of Cardiology, Bulent Ecevit University, School of Medicine, 
      Zonguldak, Turkey.
FAU - Karabag, Turgut
AU  - Karabag T
AD  - Department of Cardiology, Bulent Ecevit University, School of Medicine, 
      Zonguldak, Turkey.
FAU - Sayin, Muhammet Rasit
AU  - Sayin MR
AD  - Department of Cardiology, Bulent Ecevit University, School of Medicine, 
      Zonguldak, Turkey.
FAU - Bayraktaroglu, Taner
AU  - Bayraktaroglu T
AD  - Department of Endocrinology and Metabolism, Bulent Ecevit University, School of 
      Medicine, Zonguldak, Turkey.
FAU - Aydin, Mustafa
AU  - Aydin M
AD  - Department of Cardiology, Bulent Ecevit University, School of Medicine, 
      Zonguldak, Turkey.
LA  - eng
PT  - Journal Article
DEP - 20161206
PL  - Korea (South)
TA  - Korean J Intern Med
JT  - The Korean journal of internal medicine
JID - 8712418
SB  - IM
MH  - Adult
MH  - Atrial Fibrillation/etiology/physiopathology
MH  - Atrial Function, Left
MH  - Case-Control Studies
MH  - Diastole
MH  - Echocardiography, Doppler
MH  - Electrocardiography
MH  - Female
MH  - Heart Conduction System/physiopathology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Prediabetic State/complications/diagnostic imaging/*physiopathology
PMC - PMC5339456
OTO - NOTNLM
OT  - Atrial fibrillation
OT  - Diastolic function
OT  - Electromechanical delay
OT  - Left atrial mechanical function
OT  - Prediabetic state
COIS- No potential conflict of interest relevant to this article was reported.
EDAT- 2016/12/07 06:00
MHDA- 2017/08/25 06:00
PMCR- 2017/03/01
CRDT- 2016/12/07 06:00
PHST- 2014/12/15 00:00 [received]
PHST- 2015/07/24 00:00 [revised]
PHST- 2015/10/01 00:00 [accepted]
PHST- 2016/12/07 06:00 [pubmed]
PHST- 2017/08/25 06:00 [medline]
PHST- 2016/12/07 06:00 [entrez]
PHST- 2017/03/01 00:00 [pmc-release]
AID - kjim.2014.380 [pii]
AID - kjim-2014-380 [pii]
AID - 10.3904/kjim.2014.380 [doi]
PST - ppublish
SO  - Korean J Intern Med. 2017 Mar;32(2):286-294. doi: 10.3904/kjim.2014.380. Epub 
      2016 Dec 6.