PMID- 27928290
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20191120
IS  - 0165-8107 (Print)
IS  - 1744-506X (Electronic)
IS  - 0165-8107 (Linking)
VI  - 38
IP  - 3
DP  - 2014
TI  - Neuromyelitis Optica Spectrum Disorder in a Chinese Woman with Ocular Myasthenia 
      Gravis: First Reported Case in the Chinese Population.
PG  - 140-144
AB  - Coexisting myasthenia gravis and neuromyelitis optica spectrum disorder was 
      reported as a rare association, with only 26 reported cases in the literature. 
      The authors report the case of a middle-aged Chinese woman with bilateral 
      recurrent optic neuritis and seropositive ocular myasthenia gravis who was 
      subsequently diagnosed with neuromyelitis optica spectrum. She was tested 
      seropositive for the neuromyelitis optica immunoglobulin G (NMO-IgG) and had 
      elevated antinuclear antibody titres, but workup for other autoimmune disorders 
      were negative. She was subsequently prescribed with azathioprine and 
      pyridostigmine, and showed good control of both autoimmune disorders. To the best 
      of the authors' knowledge, this is the first reported case in the literature of a 
      Chinese patient with seropositivity for both anti-acetylcholine receptor and 
      NMO-IgG without a thymic disorder. Testing of NMO-IgG may be considered in 
      patients with optic neuritis with underlying autoimmune disorders even in the 
      absence of transverse myelitis for the detection of associated neuromyelitis 
      optica spectrum disorders.
FAU - Yau, Gordon S K
AU  - Yau GS
AD  - Department of Ophthalmology, Caritas Medical Centre Kowloon Hong Kong Special 
      Administrative Region.
FAU - Lee, Jacky W Y
AU  - Lee JW
AD  - Department of Ophthalmology, Caritas Medical Centre Kowloon Hong Kong Special 
      Administrative Region.
FAU - Chan, Theo T K
AU  - Chan TT
AD  - Department of Anatomy, Faculty of Medicine, University of Hong Kong Pokfulam Hong 
      Kong Special Administrative Region.
FAU - Yuen, Can Y F
AU  - Yuen CY
AD  - Department of Ophthalmology, Caritas Medical Centre Kowloon Hong Kong Special 
      Administrative Region.
LA  - eng
PT  - Case Reports
DEP - 20140402
PL  - England
TA  - Neuroophthalmology
JT  - Neuro-ophthalmology (Aeolus Press)
JID - 8408966
PMC - PMC5123045
OTO - NOTNLM
OT  - NMO-IgG seropositivity
OT  - Neuromyelitis optica
OT  - ocular myasthenia
EDAT- 2014/04/02 00:00
MHDA- 2014/04/02 00:01
PMCR- 2014/04/02
CRDT- 2016/12/09 06:00
PHST- 2013/10/24 00:00 [received]
PHST- 2013/12/17 00:00 [revised]
PHST- 2013/12/25 00:00 [accepted]
PHST- 2016/12/09 06:00 [entrez]
PHST- 2014/04/02 00:00 [pubmed]
PHST- 2014/04/02 00:01 [medline]
PHST- 2014/04/02 00:00 [pmc-release]
AID - 879903 [pii]
AID - 10.3109/01658107.2013.879903 [doi]
PST - epublish
SO  - Neuroophthalmology. 2014 Apr 2;38(3):140-144. doi: 10.3109/01658107.2013.879903. 
      eCollection 2014.