PMID- 27933553
OWN - NLM
STAT- MEDLINE
DCOM- 20170302
LR  - 20200930
IS  - 1573-3017 (Electronic)
IS  - 0963-9292 (Print)
IS  - 0963-9292 (Linking)
VI  - 26
IP  - 1
DP  - 2017 Jan
TI  - Spontaneous honeybee behaviour is altered by persistent organic pollutants.
PG  - 141-150
LID - 10.1007/s10646-016-1749-0 [doi]
AB  - The effect of environmental pollutants on honeybee behaviour has focused mainly 
      on currently used pesticides. However, honeybees are also exposed to persistent 
      organic pollutants (POPs). The aim of this laboratory based study was to 
      determine if exposure to sublethal field-relevant concentrations of POPs altered 
      the spontaneous behaviour of foraging-age worker honeybees. Honeybees (Apis 
      mellifera) were orally exposed to either a sublethal concentration of the 
      polychlorinated biphenyl (PCB) mixture Aroclor 1254 (100 ng/ml), the 
      organochlorine insecticide lindane (2.91 ng/ml) or vehicle (0.01% DMSO, 0.00015% 
      ethanol in 1M sucrose) for 1-4 days. The frequency of single event behaviours and 
      the time engaged in one of four behavioural states (walking, flying, upside down 
      and stationary) were monitored for 15 min after 1, 2, 3 and 4 days exposure. 
      Exposure to Aroclor 1254 but not lindane increased the frequency and time engaged 
      in honeybee motor activity behaviours in comparison to vehicle. The Aroclor 
      1254-induced hyperactivity was evident after 1 day of exposure and persisted with 
      repeated daily exposure. In contrast, 1 day of exposure to lindane elicited 
      abdominal spasms and increased the frequency of grooming behaviours in comparison 
      to vehicle exposure. After 4 days of exposure, abdominal spasms and increased 
      grooming behaviours were also evident in honeybees exposed to Aroclor 1254. These 
      data demonstrate that POPs can induce distinct behavioural patterns, indicating 
      different toxicokinetic and toxicodynamic properties. The changes in spontaneous 
      behaviour, particularly the PCB-induced chronic hyperactivity and the associated 
      energy demands, may have implications for colony health.
FAU - Drummond, Jade
AU  - Drummond J
AD  - Medical Toxicology Centre, Newcastle University, Newcastle upon Tyne, NE2 4AA, 
      UK.
AD  - Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, NE2 4HH, 
      UK.
FAU - Williamson, Sally M
AU  - Williamson SM
AD  - Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, NE2 4HH, 
      UK.
FAU - Fitchett, Ann E
AU  - Fitchett AE
AD  - Medical Toxicology Centre, Newcastle University, Newcastle upon Tyne, NE2 4AA, 
      UK.
AD  - Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, NE2 4HH, 
      UK.
FAU - Wright, Geraldine A
AU  - Wright GA
AD  - Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, NE2 4HH, 
      UK.
FAU - Judge, Sarah J
AU  - Judge SJ
AD  - Medical Toxicology Centre, Newcastle University, Newcastle upon Tyne, NE2 4AA, 
      UK. s.j.judge@ncl.ac.uk.
AD  - Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, NE2 4HH, 
      UK. s.j.judge@ncl.ac.uk.
LA  - eng
PT  - Journal Article
DEP - 20161208
PL  - United States
TA  - Ecotoxicology
JT  - Ecotoxicology (London, England)
JID - 9885956
RN  - 0 (Environmental Pollutants)
RN  - 0 (Hydrocarbons, Chlorinated)
RN  - 0 (Insecticides)
RN  - 11097-69-1 (Chlorodiphenyl (54% Chlorine))
RN  - 59NEE7PCAB (Hexachlorocyclohexane)
RN  - DFC2HB4I0K (Polychlorinated Biphenyls)
SB  - IM
MH  - Animals
MH  - Bees/*physiology
MH  - Behavior, Animal/*drug effects
MH  - Chlorodiphenyl (54% Chlorine)/toxicity
MH  - Environmental Pollutants/*toxicity
MH  - Hexachlorocyclohexane/toxicity
MH  - Hydrocarbons, Chlorinated/toxicity
MH  - Insecticides
MH  - Polychlorinated Biphenyls/toxicity
PMC - PMC5241328
OTO - NOTNLM
OT  - Apis mellifera
OT  - Honeybee
OT  - Lindane
OT  - Pesticide
OT  - Pollutant
OT  - Polychlorinated biphenyl
COIS- Compliance with Ethical Standards All applicable international, national, and/or 
      institutional guidelines for the care and use of animals were followed. All 
      procedures performed were in accordance with the ethical standards of Newcastle 
      University, UK. This article does not contain any studies with human participants 
      performed by any of the authors. Conflict of Interest The authors declare that 
      they have no conflict of interest.
EDAT- 2016/12/10 06:00
MHDA- 2017/03/03 06:00
PMCR- 2016/12/08
CRDT- 2016/12/10 06:00
PHST- 2016/11/20 00:00 [accepted]
PHST- 2016/12/10 06:00 [pubmed]
PHST- 2017/03/03 06:00 [medline]
PHST- 2016/12/10 06:00 [entrez]
PHST- 2016/12/08 00:00 [pmc-release]
AID - 10.1007/s10646-016-1749-0 [pii]
AID - 1749 [pii]
AID - 10.1007/s10646-016-1749-0 [doi]
PST - ppublish
SO  - Ecotoxicology. 2017 Jan;26(1):141-150. doi: 10.1007/s10646-016-1749-0. Epub 2016 
      Dec 8.