PMID- 27979203 OWN - NLM STAT- MEDLINE DCOM- 20170221 LR - 20191210 IS - 1873-7072 (Electronic) IS - 0308-8146 (Linking) VI - 221 DP - 2017 Apr 15 TI - Different effectiveness of two pastas supplemented with either lipophilic or hydrophilic/phenolic antioxidants in affecting serum as evaluated by the novel Antioxidant/Oxidant Balance approach. PG - 278-288 LID - S0308-8146(16)31667-3 [pii] LID - 10.1016/j.foodchem.2016.10.050 [doi] AB - Effectiveness in improving serum antioxidant status of two functional pastas was evaluated by the novel Antioxidant/Oxidant Balance (AOB) parameter, calculated as Antioxidant Capacity (AC)/Peroxide Level ratio, assessed here for the first time. In particular, Bran Oleoresin (BO) and Bran Water (BW) pastas, enriched respectively with either lipophilic (tocochromanols, carotenoids) or hydrophilic/phenolic antioxidants extracted from durum wheat bran, were studied. Notably, BO pasta was able to improve significantly (+65%) serum AOB during four hours after intake similarly to Lisosan G, a wheat antioxidant-rich dietary supplement. Contrarily, BW pasta had oxidative effect on serum so as conventional pasta and glucose, thus suggesting greater effectiveness of lipophilic than hydrophilic/phenolic antioxidants under our experimental conditions. Interestingly, no clear differences between the two pastas were observed, when AC measurements of either serum after pasta intake or pasta extracts by in vitro assays were considered, thus strengthening effectiveness and reliability of AOB approach. CI - Copyright (c) 2016 Elsevier Ltd. All rights reserved. FAU - Laus, Maura N AU - Laus MN AD - Dipartimento di Scienze Agrarie, degli Alimenti e dell'Ambiente, Universita degli Studi di Foggia, Via Napoli, 25, 71122 Foggia, Italy. Electronic address: maura.laus@unifg.it. FAU - Soccio, Mario AU - Soccio M AD - Dipartimento di Scienze Agrarie, degli Alimenti e dell'Ambiente, Universita degli Studi di Foggia, Via Napoli, 25, 71122 Foggia, Italy. Electronic address: mario.soccio@unifg.it. FAU - Alfarano, Michela AU - Alfarano M AD - Dipartimento di Scienze Agrarie, degli Alimenti e dell'Ambiente, Universita degli Studi di Foggia, Via Napoli, 25, 71122 Foggia, Italy. Electronic address: michela.alfarano@unifg.it. FAU - Pasqualone, Antonella AU - Pasqualone A AD - Dipartimento di Scienze del Suolo, della Pianta e degli Alimenti, Universita di Bari "Aldo Moro", Via Amendola, 165A, 70126 Bari, Italy. Electronic address: antonella.pasqualone@uniba.it. FAU - Lenucci, Marcello S AU - Lenucci MS AD - Dipartimento di Scienze e Tecnologie Biologiche ed Ambientali, Universita del Salento, Via Prov.le Lecce-Monteroni, 73100 Lecce, Italy. Electronic address: marcello.lenucci@unisalento.it. FAU - Di Miceli, Giuseppe AU - Di Miceli G AD - Dipartimento di Scienze Agrarie e Forestali, Universita degli Studi di Palermo, Viale delle Scienze, 90128 Palermo, Italy; Fondazione Angelo e Salvatore Lima Mancuso, Piazza Marina, 61, 90100 Palermo, Italy. Electronic address: giuseppe.dimiceli@unipa.it. FAU - Pastore, Donato AU - Pastore D AD - Dipartimento di Scienze Agrarie, degli Alimenti e dell'Ambiente, Universita degli Studi di Foggia, Via Napoli, 25, 71122 Foggia, Italy. Electronic address: donato.pastore@unifg.it. LA - eng PT - Evaluation Study PT - Journal Article DEP - 20161013 PL - England TA - Food Chem JT - Food chemistry JID - 7702639 RN - 0 (Antioxidants) RN - 0 (Oxidants) RN - 0 (Phenols) RN - 0 (Plant Extracts) RN - 0 (oleoresins) RN - 36-88-4 (Carotenoids) SB - IM MH - Adult MH - Antioxidants/*analysis/chemistry MH - Carotenoids MH - Dietary Supplements MH - Female MH - Humans MH - Male MH - Oxidants/*chemistry MH - Oxidation-Reduction MH - Phenols/*analysis MH - Plant Extracts/chemistry MH - Reproducibility of Results MH - Serum/*chemistry MH - Triticum/*chemistry MH - Young Adult OTO - NOTNLM OT - AAPH, 2,2'-azobis(2-methylpropionamidine) dihydrochloride (PubChem CID: 76344) OT - ABTS, diammonium-2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonate) (PubChem CID: 9570474) OT - DPPD, N,N-diethyl-p-phenylenediamine (PubChem CID: 7120) OT - Durum wheat antioxidants OT - Fluorescein, 3',6'-dihydroxy-3H-spiro[2-benzofuran-1,9'-xanthen]-3-one (PubChem CID: 16850) OT - Functional pasta OT - Human serum OT - LOX-FL OT - Linoleic acid sodium salt (PubChem CID: 23702140) OT - Lisosan G OT - ORAC OT - TEAC OT - Trolox, (+/-)-6-hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid (PubChem CID: 40634). EDAT- 2016/12/17 06:00 MHDA- 2017/02/22 06:00 CRDT- 2016/12/17 06:00 PHST- 2016/07/08 00:00 [received] PHST- 2016/10/11 00:00 [revised] PHST- 2016/10/11 00:00 [accepted] PHST- 2016/12/17 06:00 [entrez] PHST- 2016/12/17 06:00 [pubmed] PHST- 2017/02/22 06:00 [medline] AID - S0308-8146(16)31667-3 [pii] AID - 10.1016/j.foodchem.2016.10.050 [doi] PST - ppublish SO - Food Chem. 2017 Apr 15;221:278-288. doi: 10.1016/j.foodchem.2016.10.050. Epub 2016 Oct 13.