PMID- 27990593 OWN - NLM STAT- MEDLINE DCOM- 20170425 LR - 20181113 IS - 1613-2254 (Electronic) IS - 1346-4523 (Linking) VI - 44 IP - 2 DP - 2017 Apr TI - Is the unaffected eye really unaffected? Color Doppler ultrasound findings in unilaterally active central serous chorioretinopathy. PG - 173-181 LID - 10.1007/s10396-016-0762-5 [doi] AB - PURPOSE: To evaluate ocular hemodynamic changes using color Doppler ultrasonography imaging (CDI) with an emphasis on unaffected eyes of patients with central serous chorioretinopathy (CSC). METHODS: Twenty-seven patients with active CSC and 25 controls were analyzed using spectral domain-optical coherence tomography (SD-OCT) and CDI for choroidal imaging and evaluation of retrobulbar vessels, respectively. RESULTS: Resistive index (RI), pulsatility index (PI), and peak systolic velocity (PSV) of the ophthalmic artery (OA) and PSV, end-diastolic velocity (EDV), and mean velocity (Vmean) of the central retinal artery (CRA) in the patient group were less than those in the control group. RI and PI of the CRA were greater in the patient group compared to the control group. RI, PI, PSV, and Vmean of the OA and PSV, EDV, and Vmean of the CRA in the patients' unaffected eyes were less than those in the control group. OCT measurements of central choroidal thickness (CCT) of the affected eyes in the patient group were significantly greater than those of the unaffected eyes in the patient and control groups; that of the unaffected eyes was greater than that in the control group. CONCLUSIONS: Hemodynamic changes in OA reflect choroidal hyperperfusion. Hemodynamic and OCT changes in the unaffected eyes of the patient group suggest CSC as a bilateral disorder and the systemic nature of the disease. Further investigations may aid in the evaluation of treatment response and the follow-up of disease, providing a new insight into management strategies. FAU - Erdem Toslak, Iclal AU - Erdem Toslak I AUID- ORCID: 0000-0002-1947-8341 AD - Department of Radiology, Antalya Training and Research Hospital, Antalya, Turkey. driclalerdem@yahoo.com. AD - Department of Radiology, Loyola University Medical Center, 2160 S 1st Ave, Maywood, IL, 60153, USA. driclalerdem@yahoo.com. FAU - Erol, Muhammet Kazim AU - Erol MK AD - Department of Ophthalmology, Antalya Training and Research Hospital, Antalya, Turkey. FAU - Toslak, Devrim AU - Toslak D AD - Department of Ophthalmology, Antalya Training and Research Hospital, Antalya, Turkey. FAU - Cekic, Bulent AU - Cekic B AD - Department of Radiology, Antalya Training and Research Hospital, Antalya, Turkey. FAU - Barc Ergun, Mehtap AU - Barc Ergun M AD - Department of Radiology, Antalya Training and Research Hospital, Antalya, Turkey. FAU - Lim-Dunham, Jennifer E AU - Lim-Dunham JE AD - Department of Radiology, Loyola University Medical Center, 2160 S 1st Ave, Maywood, IL, 60153, USA. LA - eng PT - Journal Article DEP - 20161218 PL - Japan TA - J Med Ultrason (2001) JT - Journal of medical ultrasonics (2001) JID - 101128385 SB - IM MH - Adult MH - Central Serous Chorioretinopathy/*diagnostic imaging/physiopathology MH - Eye/blood supply/*diagnostic imaging MH - Female MH - Hemodynamics MH - Humans MH - Male MH - Prospective Studies MH - Regional Blood Flow MH - Tomography, Optical Coherence MH - *Ultrasonography, Doppler, Color/methods OTO - NOTNLM OT - Central serous chorioretinopathy OT - Choroidal thickness OT - Color Doppler ultrasonography OT - Fellow eye OT - Optical coherence tomography EDAT- 2016/12/19 06:00 MHDA- 2017/04/26 06:00 CRDT- 2016/12/20 06:00 PHST- 2016/07/01 00:00 [received] PHST- 2016/10/20 00:00 [accepted] PHST- 2016/12/19 06:00 [pubmed] PHST- 2017/04/26 06:00 [medline] PHST- 2016/12/20 06:00 [entrez] AID - 10.1007/s10396-016-0762-5 [pii] AID - 10.1007/s10396-016-0762-5 [doi] PST - ppublish SO - J Med Ultrason (2001). 2017 Apr;44(2):173-181. doi: 10.1007/s10396-016-0762-5. Epub 2016 Dec 18.