PMID- 27992872
OWN - NLM
STAT- MEDLINE
DCOM- 20170223
LR  - 20170223
IS  - 1423-0259 (Electronic)
IS  - 0030-3747 (Linking)
VI  - 57
IP  - 2
DP  - 2017
TI  - Long-Term Anatomical and Functional Outcomes after Combined Cataract and 
      Idiopathic Epiretinal Membrane Surgery.
PG  - 125-134
LID - 10.1159/000452837 [doi]
AB  - PURPOSE: To describe the 2-year functional and anatomical outcomes in patients 
      operated on for combined cataract and idiopathic epiretinal membrane (ERM) and to 
      study the relationship between best-corrected visual acuity (BCVA) and 
      spectral-domain optical coherence tomography (SD-OCT) throughout the follow-up. 
      METHODS: This retrospective observational case series included 72 eyes operated 
      on for combined cataract and idiopathic ERM. They were followed with clinical and 
      SD-OCT examinations preoperatively and 1, 6, 12, and 24 months after surgery. 
      Foveolar thickness (FT), photoreceptor status and morphological parameters were 
      assessed. RESULTS: BCVA and FT substantially improved at 24 months. 
      Postoperatively, no significant improvement was observed beyond 6 months for BCVA 
      and 12 months for FT. Outer limiting membrane and inner and outer segment 
      junction disruption scores were well correlated with BCVA both pre- and 
      postoperatively, and significant visual improvement was demonstrated in each 
      subgroup except in those with the highest scores. FT was correlated with BCVA 
      only from 6 to 24 months postoperatively. CONCLUSION: After combined cataract and 
      idiopathic ERM surgery, BCVA and FT improved rapidly. Most functional and 
      anatomical recovery took place within the first 6 months, but this did not 
      preclude late improvement, in particular in patients with the most disorganized 
      photoreceptor layers. At each time point, the amount of photoreceptor damage 
      seemed closely correlated with visual acuity, but concerning FT, this 
      relationship remains questionable.
CI  - (c) 2016 S. Karger AG, Basel.
FAU - Kauffmann, Yann
AU  - Kauffmann Y
AD  - Ophthalmology Department, University Hospital, Dijon, France.
FAU - Ramel, Jean-Christophe
AU  - Ramel JC
FAU - Isaico, Rodica
AU  - Isaico R
FAU - De Lazzer, Aurelie
AU  - De Lazzer A
FAU - Bron, Alain M
AU  - Bron AM
FAU - Creuzot-Garcher, Catherine
AU  - Creuzot-Garcher C
LA  - eng
PT  - Journal Article
PT  - Observational Study
DEP - 20161220
PL  - Switzerland
TA  - Ophthalmic Res
JT  - Ophthalmic research
JID - 0267442
SB  - IM
MH  - Aged
MH  - Cataract/complications/diagnosis/*physiopathology
MH  - Cataract Extraction/*methods
MH  - Epiretinal Membrane/complications/*physiopathology/surgery
MH  - Female
MH  - Follow-Up Studies
MH  - Fovea Centralis/*diagnostic imaging
MH  - Humans
MH  - Male
MH  - Retrospective Studies
MH  - Time Factors
MH  - Tomography, Optical Coherence/*methods
MH  - Treatment Outcome
MH  - Visual Acuity/*physiology
EDAT- 2016/12/20 06:00
MHDA- 2017/02/24 06:00
CRDT- 2016/12/20 06:00
PHST- 2016/07/08 00:00 [received]
PHST- 2016/10/24 00:00 [accepted]
PHST- 2016/12/20 06:00 [pubmed]
PHST- 2017/02/24 06:00 [medline]
PHST- 2016/12/20 06:00 [entrez]
AID - 000452837 [pii]
AID - 10.1159/000452837 [doi]
PST - ppublish
SO  - Ophthalmic Res. 2017;57(2):125-134. doi: 10.1159/000452837. Epub 2016 Dec 20.