PMID- 28001376
OWN - NLM
STAT- MEDLINE
DCOM- 20170307
LR  - 20231213
IS  - 1520-5010 (Electronic)
IS  - 0893-228X (Print)
IS  - 0893-228X (Linking)
VI  - 30
IP  - 1
DP  - 2017 Jan 17
TI  - Thirdhand Smoke: New Evidence, Challenges, and Future Directions.
PG  - 270-294
LID - 10.1021/acs.chemrestox.6b00343 [doi]
AB  - Thirdhand smoke (THS) is the contamination that persists after secondhand tobacco 
      smoke has been emitted into air. It refers to the tobacco-related gases and 
      particles that become embedded in materials, such as the carpet, walls, 
      furniture, blankets, and toys. THS is not strictly smoke, but chemicals that 
      adhere to surfaces from which they can be released back into the air, undergo 
      chemical transformations and/or accumulate. Currently, the hazards of THS are not 
      as well documented as the hazards of secondhand smoke (SHS). In this Perspective, 
      we describe the distribution and chemical changes that occur as SHS is 
      transformed into THS, studies of environmental contamination by THS, human 
      exposure studies, toxicology studies using animal models and in vitro systems, 
      possible approaches for avoiding exposure, remediation of THS contamination, and 
      priorities for further research.
FAU - Jacob, Peyton 3rd
AU  - Jacob P 3rd
AUID- ORCID: 0000-0003-3366-2775
AD  - Division of Clinical Pharmacology and Experimental Therapeutics, Departments of 
      Psychiatry and Medicine, University of California , San Francisco, California 
      94143, United States.
FAU - Benowitz, Neal L
AU  - Benowitz NL
AD  - Division of Clinical Pharmacology and Experimental Therapeutics, Medical Service, 
      Departments of Medicine, and Bioengineering & Therapeutic Sciences, University of 
      California , San Francisco, California 94143, United States.
AD  - Center for Tobacco Control Research and Education, University of California , San 
      Francisco, California 94143, United States.
FAU - Destaillats, Hugo
AU  - Destaillats H
AD  - Indoor Environment Group, Lawrence Berkeley National Laboratory , Berkeley, 
      California 94720, United States.
FAU - Gundel, Lara
AU  - Gundel L
AD  - Indoor Environment Group, Lawrence Berkeley National Laboratory , Berkeley, 
      California 94720, United States.
FAU - Hang, Bo
AU  - Hang B
AD  - Biological Systems & Engineering, Lawrence Berkeley National Laboratory , 
      Berkeley, California 94720, United States.
FAU - Martins-Green, Manuela
AU  - Martins-Green M
AD  - Department of Cell Biology and Neuroscience, University of California Riverside 
      92521, United States.
FAU - Matt, Georg E
AU  - Matt GE
AD  - Department of Psychology, San Diego State University , San Diego, California 
      92182, United States.
FAU - Quintana, Penelope J E
AU  - Quintana PJ
AD  - Graduate School of Public Health, San Diego State University , San Diego, 
      California 92182, United States.
FAU - Samet, Jonathan M
AU  - Samet JM
AD  - Department of Preventive Medicine, The Keck School of Medicine, University of 
      Southern California , Los Angeles, California 90089, United States.
FAU - Schick, Suzaynn F
AU  - Schick SF
AD  - Division of Occupational and Environmental Medicine, School of Medicine, 
      University of California , San Francisco, California 94143, United States.
FAU - Talbot, Prue
AU  - Talbot P
AD  - Department of Cell Biology and Neuroscience, University of California Riverside 
      92521, United States.
FAU - Aquilina, Noel J
AU  - Aquilina NJ
AD  - Department of Geosciences, University of Malta , Msida, MSD 2080, Malta.
FAU - Hovell, Melbourne F
AU  - Hovell MF
AD  - Graduate School of Public Health, San Diego State University , San Diego, 
      California 92182, United States.
FAU - Mao, Jian-Hua
AU  - Mao JH
AD  - Biological Systems & Engineering, Lawrence Berkeley National Laboratory , 
      Berkeley, California 94720, United States.
FAU - Whitehead, Todd P
AU  - Whitehead TP
AD  - The Center for Integrative Research on Childhood Leukemia and the Environment, 
      School of Public Health, University of California , Berkeley, 94704, United 
      States.
LA  - eng
GR  - P30 DA012393/DA/NIDA NIH HHS/United States
GR  - S10 RR026437/RR/NCRR NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, Non-P.H.S.
DEP - 20161221
PL  - United States
TA  - Chem Res Toxicol
JT  - Chemical research in toxicology
JID - 8807448
RN  - 0 (Particulate Matter)
RN  - 0 (Smoke)
SB  - IM
MH  - Air Pollution, Indoor/*analysis
MH  - Animals
MH  - Environmental Exposure/adverse effects/analysis
MH  - Humans
MH  - Particulate Matter/analysis/toxicity
MH  - *Smoke
MH  - *Nicotiana
PMC - PMC5501723
MID - NIHMS869843
EDAT- 2016/12/22 06:00
MHDA- 2017/03/08 06:00
PMCR- 2018/01/17
CRDT- 2016/12/22 06:00
PHST- 2016/12/22 06:00 [pubmed]
PHST- 2017/03/08 06:00 [medline]
PHST- 2016/12/22 06:00 [entrez]
PHST- 2018/01/17 00:00 [pmc-release]
AID - 10.1021/acs.chemrestox.6b00343 [doi]
PST - ppublish
SO  - Chem Res Toxicol. 2017 Jan 17;30(1):270-294. doi: 10.1021/acs.chemrestox.6b00343. 
      Epub 2016 Dec 21.