PMID- 28003370
OWN - NLM
STAT- MEDLINE
DCOM- 20171004
LR  - 20220316
IS  - 1464-3677 (Electronic)
IS  - 1353-4505 (Linking)
VI  - 29
IP  - 1
DP  - 2017 Feb 1
TI  - A literature-based economic evaluation of healthcare preventable adverse events 
      in Europe.
PG  - 9-18
LID - 10.1093/intqhc/mzw143 [doi]
AB  - PURPOSE: To establish from the literature, cost of preventable adverse events 
      (PAEs) to member states of the Joint Action European Union Network for Patient 
      Safety and Quality of Care. DATA SOURCES: We searched MEDLINE, EMBASE and CINAHL 
      for studies in Europe estimating cost of adverse events (AEs) and PAEs 
      (2000-March 2016). Using data from the literature, we estimated PAE costs based 
      on national 2013 total health expenditure (THE) data reported by World Health 
      Organization and converted to 2015 Euros. STUDY SELECTION/DATA EXTRACTION: 
      Information on type, frequency and incremental cost per episode or estimated cost 
      of AEs was extracted. Total annual disability-adjusted life years (DALYs) 
      resulting from PAEs in 30 EU nations were calculated using an estimate from a 
      published study and adjusted for the percentage of AEs considered preventable. 
      RESULT OF DATA SYNTHESIS: Published estimates of costs of AEs and PAEs vary based 
      on the care setting, methodology, population and year conducted. Only one study 
      was from primary care, the majority were conducted in acute care. Nine studies 
      estimated percentage of THE caused by AEs, 13 studies calculated attributable 
      length of stay. We estimated the annual cost of PAEs to the 30 nations in 2015 to 
      be in the range of 17-38 billion Euros, total DALYs lost from AEs as 3.5 million, 
      of which 1.5 million DALYs were likely due to PAEs. CONCLUSION: The economic 
      burden of AEs and PAEs is substantial. However, whether patient safety 
      interventions will be 'cost saving' depends on the effectiveness and costs of the 
      interventions.
CI  - (c) The Author 2016. Published by Oxford University Press in association with the 
      International Society for Quality in Health Care. All rights reserved. For 
      permissions, please e-mail: journals.permissions@oup.com
FAU - Agbabiaka, Taofikat B
AU  - Agbabiaka TB
AD  - Patient Safety, NHS Improvement, UK.
FAU - Lietz, Martina
AU  - Lietz M
AD  - Institute for Patient Safety, University Hospital Bonn, Bonn, Germany.
FAU - Mira, Jose J
AU  - Mira JJ
AD  - Alicante-Sant Joan Health District, Conselleria de Sanidad, Alicante, Spain.
AD  - Universidad Miguel Hernandez, Elche, Spain.
FAU - Warner, Bruce
AU  - Warner B
AD  - Medical Directorate, NHS England, UK.
LA  - eng
PT  - Journal Article
PL  - England
TA  - Int J Qual Health Care
JT  - International journal for quality in health care : journal of the International 
      Society for Quality in Health Care
JID - 9434628
SB  - IM
MH  - European Union/*statistics & numerical data
MH  - Health Expenditures/statistics & numerical data
MH  - Humans
MH  - Medical Errors/*adverse effects/*economics
MH  - Outcome Assessment, Health Care/economics
MH  - *Patient Safety/economics
MH  - Primary Health Care/statistics & numerical data
MH  - *Quality-Adjusted Life Years
OTO - NOTNLM
OT  - adverse event
OT  - disability-adjusted life years
OT  - economic evaluation
OT  - patient safety
EDAT- 2016/12/23 06:00
MHDA- 2017/10/05 06:00
CRDT- 2016/12/23 06:00
PHST- 2015/11/10 00:00 [received]
PHST- 2016/11/16 00:00 [accepted]
PHST- 2016/12/23 06:00 [pubmed]
PHST- 2017/10/05 06:00 [medline]
PHST- 2016/12/23 06:00 [entrez]
AID - mzw143 [pii]
AID - 10.1093/intqhc/mzw143 [doi]
PST - ppublish
SO  - Int J Qual Health Care. 2017 Feb 1;29(1):9-18. doi: 10.1093/intqhc/mzw143.