PMID- 28003741 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20240326 IS - 1177-889X (Print) IS - 1177-889X (Electronic) IS - 1177-889X (Linking) VI - 10 DP - 2016 TI - Factors influencing the quality of life perception in patients with type 2 diabetes mellitus. PG - 2471-2477 LID - 10.2147/PPA.S124858 [doi] AB - PURPOSE: To evaluate the impact of several factors on the patient's perception on quality of life in a group of patients with type 2 diabetes mellitus (T2DM). PATIENTS AND METHODS: In this cross-sectional study, 198 patients with T2DM were enrolled according to a consecutive-case population-based study design. In all participants, the perception on the quality of life was measured using the quality of life index - diabetes version III proposed by Ferrans and Powers. We evaluated the impact of several anthropometric and diabetes-related (ie, diabetes history and quality of glycemic control) factors on the patient's perception on the quality of life. RESULTS: The presence of diabetes complications was associated with a decreased quality of life: retinopathy (1 vs 5 points; P<0.001), chronic kidney disease (-1 vs 5 points; P<0.001), and neuropathy (-1 vs 5 points; P<0.001). A significant reverse correlation was found between the patient's quality of life and depression's severity (Spearman's r=-0.345; P<0.001) and body mass index (Spearman's r=-0.158; P=0.026). A positive association between the quality of life and the quality of diabetes-related self-care activities was found (Spearman's r=0.338; P<0.001). No significant association was found between the patient's quality of life and the quality of glycemic control, diabetes duration, age, gender, or smoking status. CONCLUSION: To improve the patient's quality of life, special care should be given to the modifiable diabetes-related factors: the prevention and treatment of diabetes complications, treatment of depression, and weight loss in obese and overweight patients. FAU - Timar, Romulus AU - Timar R AD - Second Department of Internal Medicine. FAU - Velea, Iulian AU - Velea I AD - Department of Pediatrics. FAU - Timar, Bogdan AU - Timar B AD - Department of Functional Sciences. FAU - Lungeanu, Diana AU - Lungeanu D AD - Department of Functional Sciences. FAU - Oancea, Cristian AU - Oancea C AD - Department of Infectious Diseases. FAU - Roman, Deiana AU - Roman D AD - Faculty of General Medicine, "Victor Babes" University of Medicine and Pharmacy. FAU - Mazilu, Octavian AU - Mazilu O AD - First Department of Surgery, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania. LA - eng PT - Journal Article DEP - 20161208 PL - New Zealand TA - Patient Prefer Adherence JT - Patient preference and adherence JID - 101475748 PMC - PMC5158177 OTO - NOTNLM OT - diabetes complications OT - diabetes-related self-care activities OT - quality of life OT - type 2 diabetes COIS- The authors report no conflicts of interest in this work. EDAT- 2016/12/23 06:00 MHDA- 2016/12/23 06:01 PMCR- 2016/12/08 CRDT- 2016/12/23 06:00 PHST- 2016/12/23 06:00 [entrez] PHST- 2016/12/23 06:00 [pubmed] PHST- 2016/12/23 06:01 [medline] PHST- 2016/12/08 00:00 [pmc-release] AID - ppa-10-2471 [pii] AID - 10.2147/PPA.S124858 [doi] PST - epublish SO - Patient Prefer Adherence. 2016 Dec 8;10:2471-2477. doi: 10.2147/PPA.S124858. eCollection 2016.