PMID- 28004076
OWN - NLM
STAT- MEDLINE
DCOM- 20170505
LR  - 20181202
IS  - 0371-0874 (Print)
IS  - 0371-0874 (Linking)
VI  - 68
IP  - 6
DP  - 2016 Dec 25
TI  - [Research progress of Kruppel-like factor 7].
PG  - 809-815
AB  - Kruppel-like factor 7 (KLF7), a member of Kruppel-like transcription factors 
      (KLFs), also known as ubiquitous Kruppel- like factor (UKLF), is ubiquitously 
      expressed in various tissues of adult human beings. Genetics reports showed that 
      the genetic polymorphism of KLF7 is associated with obesity, type 2 diabetes, 
      mental development in human beings; and KLF7 methylation is associated with the 
      development of diffuse gastric cancer (gastric adenocarcinoma). In addition, some 
      genomics reports suggested that KLF7 is one of the key transcription factors in 
      the regulatory networks of serum markers change during the cardiovascular 
      disease. The function studies showed that KLF7 is involved in the regulation of 
      the development and function of the nervous system and adipose tissue, type 2 
      diabetes, blood diseases, as well as pluripotent cells maintenance. This review 
      summarizes the research progress of KLF7 in genetic characteristics, protein 
      structure and gene function.
FAU - Chen, Yue-Chan
AU  - Chen YC
AD  - Department of Basic Medicine, School of Medicine, Shihezi University, Shihezi 
      832000, China.
AD  - Office of Scientific Research, The First Affiliated Hospital of School of 
      Medicine, Shihezi University, Shihezi 832000, China.
FAU - Wei, Hong
AU  - Wei H
AD  - Department of Basic Medicine, School of Medicine, Shihezi University, Shihezi 
      832000, China.
FAU - Zhang, Zhi-Wei
AU  - Zhang ZW
AD  - Department of Basic Medicine, School of Medicine, Shihezi University, Shihezi 
      832000, China. zzwneau@163.com.
LA  - chi
PT  - Journal Article
PT  - Review
PL  - China
TA  - Sheng Li Xue Bao
JT  - Sheng li xue bao : [Acta physiologica Sinica]
JID - 20730130R
RN  - 0 (KLF7 protein, human)
RN  - 0 (Kruppel-Like Transcription Factors)
SB  - IM
MH  - Diabetes Mellitus, Type 2
MH  - Humans
MH  - Kruppel-Like Transcription Factors/*metabolism
MH  - Nervous System
MH  - Obesity
EDAT- 2016/12/23 06:00
MHDA- 2017/05/06 06:00
CRDT- 2016/12/23 06:00
PHST- 2016/12/23 06:00 [entrez]
PHST- 2016/12/23 06:00 [pubmed]
PHST- 2017/05/06 06:00 [medline]
PST - ppublish
SO  - Sheng Li Xue Bao. 2016 Dec 25;68(6):809-815.