PMID- 28009408
OWN - NLM
STAT- MEDLINE
DCOM- 20170807
LR  - 20221207
IS  - 1724-6016 (Electronic)
IS  - 1120-6721 (Linking)
VI  - 27
IP  - 4
DP  - 2017 Jun 26
TI  - Peripapillary choroidal thickness by enhanced depth imaging optical coherence 
      tomography: the impact of metabolic syndrome.
PG  - 428-432
LID - 10.5301/ejo.5000911 [doi]
AB  - PURPOSE: To assess the impact of metabolic syndrome (MetS) on the peripapillary 
      choroidal thickness (PPCT) and to characterize the PPCT in a Portuguese 
      population. METHODS: This prospective study included 104 eyes. Detailed medical 
      and ophthalmic examinations were performed; the PPCT was measured by 
      spectral-domain optical coherence tomography (SD-OCT) using enhanced depth 
      imaging (EDI) modality. The PPCT changes with MetS, as well as with other 
      clinical and demographic factors, were investigated. RESULTS: The mean PPCT was 
      142.4 +/- 54.0 microm (58-303 microm); it was thickest superiorly, followed by the 
      temporal, nasal, and inferior sectors. The PPCT was significantly associated with 
      axial length (p<0.001), age (p = 0.001), intraocular pressure (IOP) (p = 0.041), 
      weight (p = 0.015), and arterial hypertension (p = 0.044). The presence of MetS 
      was associated with thinner PPCT in all sectors, being statistically significant 
      in the temporal (p = 0.032) and inferotemporal (p = 0.034) sectors. CONCLUSIONS: 
      The choroidal thickness was significantly less in temporal and inferotemporal 
      sectors in patients with MetS than in controls. This may suggest vascular 
      insufficiency around the optic nerve head.
FAU - Loureiro, Monica
AU  - Loureiro M
AD  - Department of Ophthalmology, Centro Hospitalar de V. N. Gaia/Espinho, Vila Nova 
      de Gaia - Portugal.
AD  - Institute of Biomedical Sciences Abel Salazar, University of Porto, Porto - 
      Portugal.
FAU - Braga, Ana Cristina
AU  - Braga AC
AD  - ALGORITMI Centre, University of Minho, Braga - Portugal.
FAU - Meira, Dalia
AU  - Meira D
AD  - Department of Ophthalmology, Centro Hospitalar de V. N. Gaia/Espinho, Vila Nova 
      de Gaia - Portugal.
FAU - Sepulveda, Paula
AU  - Sepulveda P
AD  - Department of Ophthalmology, Centro Hospitalar de V. N. Gaia/Espinho, Vila Nova 
      de Gaia - Portugal.
FAU - Agrelos, Luis
AU  - Agrelos L
AD  - Department of Ophthalmology, Centro Hospitalar de V. N. Gaia/Espinho, Vila Nova 
      de Gaia - Portugal.
FAU - Torres, Paulo
AU  - Torres P
AD  - Institute of Biomedical Sciences Abel Salazar, University of Porto, Porto - 
      Portugal.
AD  - Department of Ophthalmology, Centro Hospitalar do Porto, Porto - Portugal.
LA  - eng
PT  - Journal Article
DEP - 20161121
PL  - United States
TA  - Eur J Ophthalmol
JT  - European journal of ophthalmology
JID - 9110772
SB  - IM
MH  - Adult
MH  - Aged
MH  - Asian People
MH  - Choroid/*pathology
MH  - Female
MH  - Humans
MH  - Intraocular Pressure/physiology
MH  - Male
MH  - Metabolic Syndrome/*pathology/physiopathology
MH  - Middle Aged
MH  - Portugal
MH  - Prospective Studies
MH  - Regression Analysis
MH  - Tomography, Optical Coherence/*methods
MH  - Tonometry, Ocular
MH  - Visual Acuity/physiology
EDAT- 2016/12/24 06:00
MHDA- 2017/08/08 06:00
CRDT- 2016/12/24 06:00
PHST- 2016/11/03 00:00 [accepted]
PHST- 2016/12/24 06:00 [pubmed]
PHST- 2017/08/08 06:00 [medline]
PHST- 2016/12/24 06:00 [entrez]
AID - 7B81079E-8DC4-4E17-9C80-808AD99949BC [pii]
AID - 10.5301/ejo.5000911 [doi]
PST - ppublish
SO  - Eur J Ophthalmol. 2017 Jun 26;27(4):428-432. doi: 10.5301/ejo.5000911. Epub 2016 
      Nov 21.