PMID- 28011048
OWN - NLM
STAT- MEDLINE
DCOM- 20170714
LR  - 20240213
IS  - 1879-355X (Electronic)
IS  - 0360-3016 (Print)
IS  - 0360-3016 (Linking)
VI  - 97
IP  - 3
DP  - 2017 Mar 1
TI  - Direct Comparison of Respiration-Correlated Four-Dimensional Magnetic Resonance 
      Imaging Reconstructed Using Concurrent Internal Navigator and External Bellows.
PG  - 596-605
LID - S0360-3016(16)33426-5 [pii]
LID - 10.1016/j.ijrobp.2016.11.004 [doi]
AB  - PURPOSE: To compare the image quality of amplitude-binned 4-dimensional magnetic 
      resonance imaging (4DMRI) reconstructed using 2 concurrent respiratory (navigator 
      and bellows) waveforms. METHODS AND MATERIALS: A prospective, 
      respiratory-correlated 4DMRI scanning program was used to acquire T2-weighted 
      single-breath 4DMRI images with internal navigator and external bellows. After a 
      10-second training waveform of a surrogate signal, 2-dimensional MRI acquisition 
      was triggered at a level (bin) and anatomic location (slice) until the bin-slice 
      table was completed for 4DMRI reconstruction. The bellows signal was always 
      collected, even when the navigator trigger was used, to retrospectively 
      reconstruct a bellows-rebinned 4DMRI. Ten volunteers participated in this 
      institutional review board-approved 4DMRI study. Four scans were acquired for 
      each subject, including coronal and sagittal scans triggered by either navigator 
      or bellows, and 6 4DMRI images (navigator-triggered, bellows-rebinned, and 
      bellows-triggered) were reconstructed. The simultaneously acquired waveforms and 
      resulting 4DMRI quality were compared using signal correlation, bin/phase shift, 
      and binning motion artifacts. The consecutive bellows-triggered 4DMRI scan was 
      used for indirect comparison. RESULTS: Correlation coefficients between the 
      navigator and bellows signals were found to be patient-specific and 
      inhalation-/exhalation-dependent, ranging from 0.1 to 0.9 because of breathing 
      irregularities (>50% scans) and commonly observed bin/phase shifts (-1.1 +/- 0.6 
      bin) in both 1-dimensional waveforms and diaphragm motion extracted from 4D 
      images. Navigator-triggered 4DMRI contained many fewer binning motion artifacts 
      at the diaphragm than did the bellows-rebinned and bellows-triggered 4DMRI scans. 
      Coronal scans were faster than sagittal scans because of the fewer slices and 
      higher achievable acceleration factors. CONCLUSIONS: Navigator-triggered 4DMRI 
      contains substantially fewer binning motion artifacts than bellows-rebinned and 
      bellows-triggered 4DMRI, primarily owing to the deviation of the external from 
      the internal surrogate. The present study compared 2 concurrent surrogates during 
      the same 4DMRI scan and their resulting 4DMRI quality. The navigator-triggered 
      4DMRI scanning protocol should be preferred to the bellows-based, especially for 
      coronal scans, for clinical respiratory motion simulation.
CI  - Copyright (c) 2016 Elsevier Inc. All rights reserved.
FAU - Li, Guang
AU  - Li G
AD  - Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, 
      New York. Electronic address: lig2@mskcc.org.
FAU - Wei, Jie
AU  - Wei J
AD  - Department of Computer Science, City College of New York, New York, New York.
FAU - Olek, Devin
AU  - Olek D
AD  - Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, 
      New York.
FAU - Kadbi, Mo
AU  - Kadbi M
AD  - Philips Healthcare, MR Therapy Cleveland, Ohio.
FAU - Tyagi, Neelam
AU  - Tyagi N
AD  - Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, 
      New York.
FAU - Zakian, Kristen
AU  - Zakian K
AD  - Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, 
      New York.
FAU - Mechalakos, James
AU  - Mechalakos J
AD  - Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, 
      New York.
FAU - Deasy, Joseph O
AU  - Deasy JO
AD  - Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, 
      New York.
FAU - Hunt, Margie
AU  - Hunt M
AD  - Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, 
      New York.
LA  - eng
GR  - P20 CA132388/CA/NCI NIH HHS/United States
GR  - P30 CA008748/CA/NCI NIH HHS/United States
GR  - U54 CA132378/CA/NCI NIH HHS/United States
GR  - U54 CA137788/CA/NCI NIH HHS/United States
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
DEP - 20161109
PL  - United States
TA  - Int J Radiat Oncol Biol Phys
JT  - International journal of radiation oncology, biology, physics
JID - 7603616
SB  - IM
MH  - Anatomic Landmarks
MH  - Artifacts
MH  - Exhalation
MH  - Female
MH  - Humans
MH  - Image Processing, Computer-Assisted/*methods
MH  - Inhalation
MH  - Magnetic Resonance Imaging/*methods
MH  - Male
MH  - *Movement
MH  - Prospective Studies
MH  - *Respiration
MH  - Retrospective Studies
PMC - PMC5288126
MID - NIHMS838416
EDAT- 2016/12/25 06:00
MHDA- 2017/07/15 06:00
PMCR- 2018/03/01
CRDT- 2016/12/25 06:00
PHST- 2016/06/14 00:00 [received]
PHST- 2016/10/29 00:00 [revised]
PHST- 2016/11/02 00:00 [accepted]
PHST- 2016/12/25 06:00 [pubmed]
PHST- 2017/07/15 06:00 [medline]
PHST- 2016/12/25 06:00 [entrez]
PHST- 2018/03/01 00:00 [pmc-release]
AID - S0360-3016(16)33426-5 [pii]
AID - 10.1016/j.ijrobp.2016.11.004 [doi]
PST - ppublish
SO  - Int J Radiat Oncol Biol Phys. 2017 Mar 1;97(3):596-605. doi: 
      10.1016/j.ijrobp.2016.11.004. Epub 2016 Nov 9.