PMID- 28028574
OWN - NLM
STAT- MEDLINE
DCOM- 20180625
LR  - 20181113
IS  - 1432-2161 (Electronic)
IS  - 0364-2348 (Linking)
VI  - 46
IP  - 3
DP  - 2017 Mar
TI  - Prospective pilot study of CT-guided microwave ablation in the treatment of 
      osteoid osteomas.
PG  - 315-323
LID - 10.1007/s00256-016-2558-5 [doi]
AB  - PURPOSE: The aims of this work were to assess the feasibility and efficacy of 
      CT-guided microwave ablation (MWA) in the treatment of osteoid osteomas (OOs). 
      MATERIALS AND METHODS: Thirteen consecutive patients (range 11-31 years old) 
      presenting with OO were prospectively included and treated by CT-guided MWA. 
      Power and duration of MWA were both recorded. The patient's pain was assessed 
      using a numeric pain rating scale (NRS), and side effects were recorded during 
      procedures, after 1 day, 7 days and 1 month. The nidus vascularization and the 
      volume of necrosis induced by MWA were assessed using contrast-enhanced MRI. 
      Success was defined as the complete relief of the patient's pain 1 month after 
      the first procedure, associated with necrosis of the nidus on follow-up MRI. 
      RESULTS: The success rate was up to 92.3% (12/13). At 1 day, 7 days and 1 month, 
      the median NRSs were respectively 5 [interquartile range (IQR) 2-5], 0 (IQR 0-1) 
      and 0 (IQR 0-0). Side effects observed were one partial and self-resolving lesion 
      of a sensory branch of the radial nerve and two skin burns. The median power of 
      the MWA used was 60 W (IQR 50-60) with a 1.5-min duration (IQR 1-2), leading to 
      MWA-induced necrosis measuring on average 23 x 15 x 16 mm. CONCLUSION: CT-guided 
      MWA of OO has a success rate that appears to be almost similar to that of laser 
      or radiofrequency ablation, but care must be taken to prevent nerve or skin 
      lesions.
FAU - Prud'homme, Clara
AU  - Prud'homme C
AD  - Department of Musculoskeletal Imaging, University Hospital of Besancon, 25000, 
      Besancon, France.
FAU - Nueffer, Jean-Philippe
AU  - Nueffer JP
AD  - Department of Musculoskeletal Imaging, University Hospital of Besancon, 25000, 
      Besancon, France.
FAU - Runge, Michel
AU  - Runge M
AD  - Department of Musculoskeletal Imaging, University Hospital of Besancon, 25000, 
      Besancon, France.
FAU - Dubut, Jonathan
AU  - Dubut J
AD  - Department of Musculoskeletal Imaging, University Hospital of Besancon, 25000, 
      Besancon, France.
FAU - Kastler, Bruno
AU  - Kastler B
AD  - Department of Musculoskeletal Imaging, University Hospital of Besancon, 25000, 
      Besancon, France.
AD  - I4S Laboratory, INSERM EA4268, University of Franche-Comte, 25000, Besancon, 
      France.
FAU - Aubry, Sebastien
AU  - Aubry S
AD  - Department of Musculoskeletal Imaging, University Hospital of Besancon, 25000, 
      Besancon, France. radio.aubry@free.fr.
AD  - Nanomedecine Laboratory, INSERM EA4662, University of Franche-Comte, 25000, 
      Besancon, France. radio.aubry@free.fr.
LA  - eng
PT  - Journal Article
DEP - 20161227
PL  - Germany
TA  - Skeletal Radiol
JT  - Skeletal radiology
JID - 7701953
RN  - 0 (Contrast Media)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Bone Neoplasms/diagnostic imaging/*surgery
MH  - Catheter Ablation/*methods
MH  - Child
MH  - Contrast Media
MH  - Female
MH  - Humans
MH  - Male
MH  - Microwaves/*therapeutic use
MH  - Osteoma, Osteoid/diagnostic imaging/*surgery
MH  - Pain Measurement
MH  - Pilot Projects
MH  - Prospective Studies
MH  - *Radiography, Interventional
MH  - *Tomography, X-Ray Computed
MH  - Treatment Outcome
OTO - NOTNLM
OT  - CT-guided procedure
OT  - Efficacy
OT  - Microwave ablation
OT  - Osteoid osteoma
OT  - Thermoablation
OT  - Treatment
EDAT- 2016/12/29 06:00
MHDA- 2018/06/26 06:00
CRDT- 2016/12/29 06:00
PHST- 2016/04/15 00:00 [received]
PHST- 2016/12/15 00:00 [accepted]
PHST- 2016/12/13 00:00 [revised]
PHST- 2016/12/29 06:00 [pubmed]
PHST- 2018/06/26 06:00 [medline]
PHST- 2016/12/29 06:00 [entrez]
AID - 10.1007/s00256-016-2558-5 [pii]
AID - 10.1007/s00256-016-2558-5 [doi]
PST - ppublish
SO  - Skeletal Radiol. 2017 Mar;46(3):315-323. doi: 10.1007/s00256-016-2558-5. Epub 
      2016 Dec 27.