PMID- 28032703 OWN - NLM STAT- MEDLINE DCOM- 20170317 LR - 20220316 IS - 1757-7861 (Electronic) IS - 1757-7853 (Print) IS - 1757-7853 (Linking) VI - 8 IP - 4 DP - 2016 Nov TI - Comparison of Anterior Cervical Discectomy and Fusion versus Posterior Cervical Foraminotomy in the Treatment of Cervical Radiculopathy: A Systematic Review. PG - 425-431 LID - 10.1111/os.12285 [doi] AB - Controversy remains over whether anterior cervical discectomy and fusion (ACDF) or posterior cervical foraminotomy (PCF) is superior for the treatment of cervical radiculopathy. We therefore performed a systematic review including three prospective randomized controlled trails (RCT) and seven retrospective comparative studies (RCoS) by searching PubMed and EMBASE. These studies were assessed on risk of bias according to the Cochrane Handbook for Systematic Reviews of Interventions, and the quality of evidence and level of recommendation were evaluated according to the GRADE approach. Clinical outcomes, complications, reoperation rates, radiological parameters, and cost/cost-utility were evaluated. The mean complication rate was 7% in the ACDF group and 4% in the PCF group, and the mean reoperation rate was 4% in the ACDF group and 6% in the PCF group within 2 years of the initial surgery. There was a strong level of recommendation that no difference existed in clinical outcome, complication rate and reoperation rate between the ACDF and the PCF group. There was conflicting evidence that the ACDF group had better clinical outcomes than the PCF group (one study with weak level of recommendation). PCF could preserve the range of motion (ROM) of the operated segment but did not increase the ROM of the adjacent segment (weak level of recommendation). Meanwhile, the average cost or cost-utility of the PCF group was significantly lower than that of the ACDF group (weak level of recommendation). In conclusion, the PCF was just as safe and effective as the ACDF in the treatment of cervical radiculopathy. Meanwhile, PCF might have lower medical cost than ACDF and decrease the incidence of adjacent segment disease. Based on the available evidence, PCF appears to be another good surgical approach in the treatment of cervical radiculopathy. CI - (c) 2016 Chinese Orthopaedic Association and John Wiley & Sons Australia, Ltd. FAU - Liu, Wei-Jun AU - Liu WJ AD - Department of Orthopaedics, Pu Ai Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. FAU - Hu, Ling AU - Hu L AD - Department of Anesthesiology, Tianyou Hospital, Wuhan University of Science and Technology, Wuhan, China. FAU - Chou, Po-Hsin AU - Chou PH AD - Department of Orthopaedics and Traumatology, Taipei Veterans General, Hospital School of Medicine, National Yang-Ming University, Taipei, Taiwan. FAU - Wang, Jun-Wen AU - Wang JW AD - Department of Orthopaedics, Pu Ai Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. FAU - Kan, Wu-Sheng AU - Kan WS AD - Department of Orthopaedics, Pu Ai Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. LA - eng PT - Comparative Study PT - Journal Article PT - Review PT - Systematic Review PL - Australia TA - Orthop Surg JT - Orthopaedic surgery JID - 101501666 SB - IM MH - Cervical Vertebrae/*surgery MH - *Diskectomy MH - *Foraminotomy MH - Humans MH - Radiculopathy/*surgery MH - *Spinal Fusion MH - Treatment Outcome PMC - PMC6584082 OTO - NOTNLM OT - Anterior cervical discectomy and fusion OT - Cervical radiculopathy OT - Posterior cervical foraminotomy OT - Systematic review EDAT- 2016/12/30 06:00 MHDA- 2017/03/18 06:00 PMCR- 2016/12/29 CRDT- 2016/12/30 06:00 PHST- 2016/03/06 00:00 [received] PHST- 2016/03/21 00:00 [accepted] PHST- 2016/12/30 06:00 [entrez] PHST- 2016/12/30 06:00 [pubmed] PHST- 2017/03/18 06:00 [medline] PHST- 2016/12/29 00:00 [pmc-release] AID - OS12285 [pii] AID - 10.1111/os.12285 [doi] PST - ppublish SO - Orthop Surg. 2016 Nov;8(4):425-431. doi: 10.1111/os.12285.