PMID- 2803406
OWN - NLM
STAT- MEDLINE
DCOM- 19891127
LR  - 20061115
IS  - 0904-1850 (Print)
IS  - 0904-1850 (Linking)
VI  - 6
DP  - 1989 Jun
TI  - Allergy and asthma: distinguishing the causes from the triggers. An eye model for 
      the study of inflammatory events following allergen challenge.
PG  - 497s-501s
AB  - The study of the late-phase reaction to allergen challenge has greatly 
      contributed to increasing understanding of the relationship existing between 
      immunoglobulin E (IgE) triggering, allergic inflammation and bronchial 
      hyperreactivity, as well as to changing our concept from "causes" to "triggers" 
      of asthma. This paper reviews personal studies on a model of conjunctival 
      provocation in allergic subjects. These studies represent the first evidence of a 
      late-phase reaction in the human eye and contribute to a better knowledge of the 
      network of cells and mediators involved in allergic inflammation which are 
      responsible for heightened bronchial reactivity in allergic asthma.
FAU - Bonini, S
AU  - Bonini S
AD  - Andrea Cesalpino Foundation, Institute of Clinica Medica, University La Sapienza, 
      Rome, Italy.
FAU - Adriani, E
AU  - Adriani E
FAU - Bonini, S
AU  - Bonini S
FAU - De Petrillo, G
AU  - De Petrillo G
FAU - Loggi, G G
AU  - Loggi GG
FAU - Adabbo, A
AU  - Adabbo A
FAU - Pani, M
AU  - Pani M
FAU - Balsano, F
AU  - Balsano F
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Eur Respir J Suppl
JT  - The European respiratory journal. Supplement
JID - 8910681
SB  - IM
MH  - Asthma/etiology/*immunology
MH  - Conjunctivitis, Allergic/etiology/*immunology/pathology
MH  - Humans
MH  - Poaceae
EDAT- 1989/06/01 00:00
MHDA- 1989/06/01 00:01
CRDT- 1989/06/01 00:00
PHST- 1989/06/01 00:00 [pubmed]
PHST- 1989/06/01 00:01 [medline]
PHST- 1989/06/01 00:00 [entrez]
PST - ppublish
SO  - Eur Respir J Suppl. 1989 Jun;6:497s-501s.