PMID- 28039598
OWN - NLM
STAT- MEDLINE
DCOM- 20180404
LR  - 20181202
IS  - 1863-4362 (Electronic)
IS  - 0021-1265 (Linking)
VI  - 186
IP  - 3
DP  - 2017 Aug
TI  - Patient acceptability and experiences of therapeutic switching of proton pump 
      inhibitors within the National Preferred Drugs initiative in Ireland.
PG  - 631-639
LID - 10.1007/s11845-016-1535-2 [doi]
AB  - INTRODUCTION: A 'Preferred Drugs' initiative was introduced into Ireland in 2013. 
      This identified a single recommended drug to be prescribed to patients requiring 
      treatment from a particular class of drugs. AIMS: This study investigates how 
      patients on established proton pump inhibitor (PPI) therapy experienced the 
      therapeutic switching of their medication to the 'preferred drug', and the extent 
      to which they regarded it as an acceptable practice. METHODS: The experiences of 
      61 patients on established proton pump inhibitor (PPI) therapy were sought before 
      and after their drug was switched to the 'preferred drug'. RESULTS: Eighty per 
      cent of patients were happy to switch medications. When asked for their opinions 
      on medications in general, 71% felt doctors should prescribe the least expensive 
      medication, 84% agreed that all licensed medications were safe while 67% felt 
      their GP changing medication for cost reasons was safe. After 8 weeks, 20% of 
      patients had switched back to their old PPI. When asked how they felt about their 
      medication change, 74% felt happy or pleased. CONCLUSIONS: The majority of 
      patients in our study were satisfied to have their medication switched. However, 
      prescribers should be mindful that 1 in 5 patients encountered problems as a 
      result of the switching process.
FAU - O'Connor, G
AU  - O'Connor G
AD  - General Practice Registrar, Trinity College Dublin/Health Service Executive 
      General Practice Training Scheme, Department of Public Health and Primary Care, 
      Trinity Centre, AMNCH, Tallaght, Dublin 24, Ireland. gearoid_oc@hotmail.com.
AD  - Department of Public Health and Primary Care, Trinity College, Dublin, Ireland. 
      gearoid_oc@hotmail.com.
FAU - O'Keeffe, D
AU  - O'Keeffe D
AD  - General Practice Registrar, Trinity College Dublin/Health Service Executive 
      General Practice Training Scheme, Department of Public Health and Primary Care, 
      Trinity Centre, AMNCH, Tallaght, Dublin 24, Ireland.
AD  - Department of Public Health and Primary Care, Trinity College, Dublin, Ireland.
FAU - Darker, C
AU  - Darker C
AD  - Department of Public Health and Primary Care, Trinity College, Dublin, Ireland.
FAU - O'Shea, B
AU  - O'Shea B
AD  - Department of Public Health and Primary Care, Trinity College, Dublin, Ireland.
LA  - eng
PT  - Journal Article
DEP - 20161230
PL  - Ireland
TA  - Ir J Med Sci
JT  - Irish journal of medical science
JID - 7806864
RN  - 0 (Proton Pump Inhibitors)
SB  - IM
MH  - Aged
MH  - Drug Costs/*statistics & numerical data
MH  - Female
MH  - Humans
MH  - Ireland
MH  - Male
MH  - Patient Acceptance of Health Care/*statistics & numerical data
MH  - Proton Pump Inhibitors/*economics/pharmacology/*therapeutic use
OTO - NOTNLM
OT  - Drug costs
OT  - Drug substitution
OT  - Preferred drugs
OT  - Proton pump inhibitors
EDAT- 2017/01/01 06:00
MHDA- 2018/04/05 06:00
CRDT- 2017/01/01 06:00
PHST- 2016/04/11 00:00 [received]
PHST- 2016/12/21 00:00 [accepted]
PHST- 2017/01/01 06:00 [pubmed]
PHST- 2018/04/05 06:00 [medline]
PHST- 2017/01/01 06:00 [entrez]
AID - 10.1007/s11845-016-1535-2 [pii]
AID - 10.1007/s11845-016-1535-2 [doi]
PST - ppublish
SO  - Ir J Med Sci. 2017 Aug;186(3):631-639. doi: 10.1007/s11845-016-1535-2. Epub 2016 
      Dec 30.