PMID- 28050429
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220408
IS  - 2249-782X (Print)
IS  - 0973-709X (Electronic)
IS  - 0973-709X (Linking)
VI  - 10
IP  - 11
DP  - 2016 Nov
TI  - Redo Mitral Valve Replacement for Prosthetic Valve Thrombosis: Single Center 
      Experience.
PG  - PC01-PC03
LID - 10.7860/JCDR/2016/20209.8913 [doi]
AB  - INTRODUCTION: Prosthetic Valve Thrombosis (PVT) remains a significant cause of 
      morbidity and mortality after valve replacement. Although surgical treatment is 
      usually preferred as life-saving in cases of obstructive PVT, optimal treatment 
      is yet to be decided. AIM: To evaluate risk factors and outcome of the patients 
      undergoing redo mitral valve surgery for acute PVT. MATERIALS AND METHODS: 
      Between January 2012 and February 2015, 65 patients underwent redo surgery for 
      obstructive PVT of mitral valve in Department of Cardiothoracic Surgery, UN Mehta 
      Institute of Cardiology & Research Centre. Patients having acute PVT of aortic 
      valve or combined aortic and mitral valve were excluded. Pre-operative, 
      intra-operative and post-operative factors affecting the outcome as well as 
      follow-up data were measured. RESULTS: There were total 65 patients, 17 males and 
      48 females. Most common presenting symptom was dyspnea (100%), followed by 
      palpitation (57.88%) and fatigue (29.45%). Total mortality was 29.2% (19/65). 
      Mortality rate was significantly higher (16/35, 46%) in patients with direct 
      surgery (Group-2) as compared to those with failed thrombolysis (3/30, 10%) 
      (Group-1). Mortality was also significantly higher in patients presented with New 
      York Heart Association (NYHA) III/IV class as compared to those presented with 
      NYHA I/II class (p=0.02). All survived patients are NYHA Class I-II in follow-up 
      with mean follow-up period was 24 +/- 9 months. CONCLUSION: PVT still remains a 
      challenging problem in a post-operative patient with a high mortality independent 
      of treatment modality. Though life-saving, the surgical management of this 
      condition still carries a high risk in haemodynamically unstable and in NYHA 
      class III/IV patients.
FAU - Kothari, Jignesh
AU  - Kothari J
AD  - Professor, Department of Cardiothoracic and Vascular Surgery, U. N. Mehta, 
      Institute of Cardiology and Research Center , New Civil Hospital Campus, Asarwa, 
      Ahmedabad, Gujarat, India .
FAU - Patel, Kartik
AU  - Patel K
AD  - Assistant Professor, Department of Cardiothoracic and Vascular Surgery, U. N. 
      Mehta, Institute of Cardiology and Research Center , New Civil Hospital Campus, 
      Asarwa, Ahmedabad, Gujarat, India .
FAU - Brahmbhatt, Bhavin
AU  - Brahmbhatt B
AD  - Resident, Department of Cardiothoracic and Vascular Surgery, U. N. Mehta, 
      Institute of Cardiology and Research Center , New Civil Hospital Campus, Asarwa, 
      Ahmedabad, Gujarat, India .
FAU - Baria, Kinnaresh
AU  - Baria K
AD  - Resident, Department of Cardiothoracic and Vascular Surgery, U. N. Mehta, 
      Institute of Cardiology and Research Center , New Civil Hospital Campus, Asarwa, 
      Ahmedabad, Gujarat, India .
FAU - Talsaria, Malkesh
AU  - Talsaria M
AD  - Resident, Department of Cardiothoracic and Vascular Surgery, U. N. Mehta, 
      Institute of Cardiology and Research Center , New Civil Hospital Campus, Asarwa, 
      Ahmedabad, Gujarat, India .
FAU - Patel, Sanjay
AU  - Patel S
AD  - Research Assistant, Department of Research, U. N. Mehta, Institute of Cardiology 
      and Research Center , New Civil Hospital Campus, Asarwa, Ahmedabad, Gujarat, 
      India .
FAU - Tailor, Sandeep
AU  - Tailor S
AD  - Perfusionist, Department of Perfusion, U. N. Mehta, Institute of Cardiology and 
      Research Center , New Civil Hospital Campus, Asarwa, Ahmedabad, Gujarat, India .
LA  - eng
PT  - Journal Article
DEP - 20161101
PL  - India
TA  - J Clin Diagn Res
JT  - Journal of clinical and diagnostic research : JCDR
JID - 101488993
PMC - PMC5198382
OTO - NOTNLM
OT  - Heart valve
OT  - Prosthetic
OT  - Redo
EDAT- 2017/01/05 06:00
MHDA- 2017/01/05 06:01
PMCR- 2017/01/01
CRDT- 2017/01/05 06:00
PHST- 2016/03/17 00:00 [received]
PHST- 2016/08/24 00:00 [accepted]
PHST- 2017/01/05 06:00 [entrez]
PHST- 2017/01/05 06:00 [pubmed]
PHST- 2017/01/05 06:01 [medline]
PHST- 2017/01/01 00:00 [pmc-release]
AID - 10.7860/JCDR/2016/20209.8913 [doi]
PST - ppublish
SO  - J Clin Diagn Res. 2016 Nov;10(11):PC01-PC03. doi: 10.7860/JCDR/2016/20209.8913. 
      Epub 2016 Nov 1.