PMID- 28050511
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201001
IS  - 2249-782X (Print)
IS  - 0973-709X (Electronic)
IS  - 0973-709X (Linking)
VI  - 10
IP  - 11
DP  - 2016 Nov
TI  - Oral Manifestations of Job's Syndrome in a Paediatric Dental Patient - A Case 
      Report.
PG  - ZD04-ZD05
LID - 10.7860/JCDR/2016/21340.8764 [doi]
AB  - Job's syndrome or Hyperimmunoglobulin E Syndrome (HIES) is a rare primary 
      immunodeficiency with marked increase in serum immunoglobulin E (IgE) levels and 
      eczematous dermatitis. Individuals with HIES share characteristic facial 
      features, with many oral manifestations like retained deciduous teeth, fissured 
      tongue, missing permanent tooth buds, recurrent oral candidiasis, oral mucosal 
      and gingival lesions. Two forms of disease have been identified based on the 
      defective gene as autosomal dominant form and autosomal recessive form. The 
      therapeutic strategies are usually directed towards prevention and management of 
      recurrent infections which are refractory to the conventional strategies. About 
      200 cases of HIES have been reported so far, in the present case report authors 
      present the oral manifestations of a paediatric dental patient affected with 
      HIES.
FAU - James, Jeswin
AU  - James J
AD  - Junior Resident, Department of Pedodontics, Government Dental College , Calicut, 
      Kerala, India .
FAU - Thekkeveetil, Anupam Kumar
AU  - Thekkeveetil AK
AD  - Associate Professor, Department of Pedodontics, Government Dental College , 
      Calicut, Kerala, India .
FAU - Vadakkepurayil, Kannan
AU  - Vadakkepurayil K
AD  - Professor and Head, Department of Pedodontics, Government Dental College , 
      Calicut, Kerala, India .
LA  - eng
PT  - Case Reports
DEP - 20161101
PL  - India
TA  - J Clin Diagn Res
JT  - Journal of clinical and diagnostic research : JCDR
JID - 101488993
PMC - PMC5198464
OTO - NOTNLM
OT  - Hyperimmunoglobulin E syndrome
OT  - Immunoglobulin E
OT  - Recurrent infections
EDAT- 2017/01/05 06:00
MHDA- 2017/01/05 06:01
PMCR- 2017/01/01
CRDT- 2017/01/05 06:00
PHST- 2016/05/12 00:00 [received]
PHST- 2016/07/11 00:00 [accepted]
PHST- 2017/01/05 06:00 [entrez]
PHST- 2017/01/05 06:00 [pubmed]
PHST- 2017/01/05 06:01 [medline]
PHST- 2017/01/01 00:00 [pmc-release]
AID - 10.7860/JCDR/2016/21340.8764 [doi]
PST - ppublish
SO  - J Clin Diagn Res. 2016 Nov;10(11):ZD04-ZD05. doi: 10.7860/JCDR/2016/21340.8764. 
      Epub 2016 Nov 1.