PMID- 28053868 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20201001 IS - 2213-5103 (Print) IS - 2213-5103 (Electronic) IS - 2213-5103 (Linking) VI - 7 IP - 1-3 DP - 2015 Dec TI - A Simple Mathematical Model for Wound Closure Evaluation. PG - 40-49 LID - 10.1016/j.jccw.2016.07.002 [doi] AB - The incidence of ulcers associated to type 2 diabetes mellitus (T2DM) increases every year. We introduce and explore a new mathematical algorithm to evaluate wound-healing in foot ulcers associated to T2DM. Fifteen patients (nine women and six men), mean age of 70 +/- 16 years were included. The evolution of their wounds followed-up for a period of 18-45 days. According to the Wagner grading system the ulcers were grade I (5 patients), grade II (9 patients), and grade III (1 patient). Clinically, the type of the ulcers was neuroischemic (12 patients) and neuropathic (3 patients). A new parameter is introduced, the "continuous linear healing rate" Dc that was more accurate with higher values and requires less quantifications than usual formulas to make a wound-healing projection. FAU - Vidal, Alejandra AU - Vidal A AD - Instituto de Anatomia, Histologia y Patologia, Facultad de Medicina, Universidad Austral de Chile, Valdivia, Chile. FAU - Mendieta Zeron, Hugo AU - Mendieta Zeron H AD - Facultad de Medicina, Universidad Autonoma del Estado de Mexico, Toluca, Estado de Mexico, Mexico. FAU - Giacaman, Israel AU - Giacaman I AD - Instituto de Anatomia, Histologia y Patologia, Facultad de Medicina, Universidad Austral de Chile, Valdivia, Chile. FAU - Camarillo Romero, Maria Del Socorro AU - Camarillo Romero MD AD - Centro de Investigacion en Ciencias Medicas (CICMED), Universidad Autonoma del Estado de Mexico, Toluca, Estado de Mexico, Mexico. FAU - Lopez, Sandra Parra AU - Lopez SP AD - Facultad de Medicina, Universidad Autonoma del Estado de Mexico, Toluca, Estado de Mexico, Mexico. FAU - Meza Trillo, Laura E AU - Meza Trillo LE AD - Facultad de Ciencias de la Salud, Universidad de Anahuac, Huixquilucan, Estado de Mexico, Mexico. FAU - Perez Perez, David A AU - Perez Perez DA AD - Universidad del Valle de Toluca, Toluca, Estado de Mexico, Mexico. FAU - Concha, Miguel AU - Concha M AD - Instituto de Anatomia, Histologia y Patologia, Facultad de Medicina, Universidad Austral de Chile, Valdivia, Chile. FAU - Torres-Gallegos, Cesar AU - Torres-Gallegos C AD - Instituto de Ciencias Quimicas, Facultad de Ciencias, Universidad Austral de Chile, Valdivia, Chile. FAU - Orellana, Sandra L AU - Orellana SL AD - Instituto de Ciencias Quimicas, Facultad de Ciencias, Universidad Austral de Chile, Valdivia, Chile. FAU - Oyarzun-Ampuero, Felipe AU - Oyarzun-Ampuero F AD - Departamento de Ciencias & Tecnologias Farmaceuticas, Universidad de Chile, Santiago, Chile. FAU - Moreno-Villoslada, Ignacio AU - Moreno-Villoslada I AD - Departamento de Ciencias & Tecnologias Farmaceuticas, Universidad de Chile, Santiago, Chile. LA - eng PT - Journal Article DEP - 20160729 PL - United States TA - J Am Coll Clin Wound Spec JT - The journal of the American College of Clinical Wound Specialists JID - 101620247 PMC - PMC5197051 OTO - NOTNLM OT - Diabetic foot OT - Foot ulcers OT - Mathematical model OT - Wounds EDAT- 2017/01/06 06:00 MHDA- 2017/01/06 06:01 PMCR- 2016/07/29 CRDT- 2017/01/06 06:00 PHST- 2017/01/06 06:00 [entrez] PHST- 2017/01/06 06:00 [pubmed] PHST- 2017/01/06 06:01 [medline] PHST- 2016/07/29 00:00 [pmc-release] AID - S2213-5103(16)30031-8 [pii] AID - 10.1016/j.jccw.2016.07.002 [doi] PST - epublish SO - J Am Coll Clin Wound Spec. 2016 Jul 29;7(1-3):40-49. doi: 10.1016/j.jccw.2016.07.002. eCollection 2015 Dec.