PMID- 28057653
OWN - NLM
STAT- MEDLINE
DCOM- 20171215
LR  - 20181113
IS  - 2044-6055 (Electronic)
IS  - 2044-6055 (Linking)
VI  - 7
IP  - 1
DP  - 2017 Jan 5
TI  - Hospitalisation with community-acquired pneumonia among patients with type 2 
      diabetes: an observational population-based study in Spain from 2004 to 2013.
PG  - e013097
LID - 10.1136/bmjopen-2016-013097 [doi]
LID - e013097
AB  - OBJECTIVES: To describe trends in the incidence and outcomes of 
      community-acquired pneumonia (CAP) hospitalisations among patients with or 
      without diabetes in Spain (2004-2013). DESIGN: Retrospective, observational study 
      using the Spanish National Hospital Discharge Database (Conjunto Minimo Basico de 
      Datos (CMBD)). SETTING: Spain. PARTICIPANTS: We used national hospital discharge 
      data to select all hospital admissions for CAP. MAIN OUTCOME MEASURES: Incidence 
      was calculated overall and stratified by diabetes status: type 2 diabetes 
      mellitus (T2DM) and no diabetes. RESULTS: We identified 901 136 admissions for 
      CAP (24.8% with T2DM). Incidence rates of CAP increased significantly in patients 
      with T2DM over time. The incidence was higher among people with T2DM for all time 
      periods. Patients with T2DM were older and had higher comorbidity index than 
      non-diabetics. Streptococcus pneumoniae decreased over time for both groups. Time 
      trend analyses showed significant decreases in mortality during admission for CAP 
      for patients with and without T2DM. Factors associated with higher mortality in 
      both groups included: older age, higher comorbidity, mechanical ventilation, red 
      cell transfusion, readmission and Staphylococcus aureus detection. Diabetes was 
      associated with a lower in-hospital mortality (OR 0.92, 95% CI 0.91 to 0.94) 
      after a CAP hospitalisation. CONCLUSIONS: CAP incidence rates were higher and 
      increased over time at a higher rate among patients with T2DM. Mortality 
      decreased over time in all groups. The presence of diabetes is not a risk factor 
      for death during admission for CAP.
CI  - Published by the BMJ Publishing Group Limited. For permission to use (where not 
      already granted under a licence) please go to 
      http://www.bmj.com/company/products-services/rights-and-licensing/.
FAU - Lopez-de-Andres, Ana
AU  - Lopez-de-Andres A
AD  - Preventive Medicine and Public Health Teaching and Research Unit, Health Sciences 
      Faculty, Rey Juan Carlos University, Madrid, Spain.
FAU - de Miguel-Diez, Javier
AU  - de Miguel-Diez J
AD  - Respiratory Care Department, Hospital General Universitario Gregorio Maranon, 
      Universidad Complutense de Madrid, Madrid, Spain.
FAU - Jimenez-Trujillo, Isabel
AU  - Jimenez-Trujillo I
AD  - Preventive Medicine and Public Health Teaching and Research Unit, Health Sciences 
      Faculty, Rey Juan Carlos University, Madrid, Spain.
FAU - Hernandez-Barrera, Valentin
AU  - Hernandez-Barrera V
AD  - Preventive Medicine and Public Health Teaching and Research Unit, Health Sciences 
      Faculty, Rey Juan Carlos University, Madrid, Spain.
FAU - de Miguel-Yanes, Jose M
AU  - de Miguel-Yanes JM
AD  - Internal Medicine Department, Hospital General Universitario Gregorio Maranon, 
      Madrid, Spain.
FAU - Mendez-Bailon, Manuel
AU  - Mendez-Bailon M
AD  - Internal Medicine Department, Hospital Universitario Clinico San Carlos, Madrid, 
      Spain.
FAU - Perez-Farinos, Napoleon
AU  - Perez-Farinos N
AD  - Health Security Agency, Ministry of Health, Social Services and Equality, Madrid, 
      Spain.
FAU - Salinero-Fort, Miguel A Ngel
AU  - Salinero-Fort MA
AD  - Direccion Tecnica de Docencia e Investigacion, Gerencia Atencion Primaria, 
      Madrid, Spain.
FAU - Jimenez-Garcia, Rodrigo
AU  - Jimenez-Garcia R
AD  - Preventive Medicine and Public Health Teaching and Research Unit, Health Sciences 
      Faculty, Rey Juan Carlos University, Madrid, Spain.
LA  - eng
PT  - Journal Article
PT  - Observational Study
PT  - Research Support, Non-U.S. Gov't
DEP - 20170105
PL  - England
TA  - BMJ Open
JT  - BMJ open
JID - 101552874
SB  - IM
MH  - Adult
MH  - Age Factors
MH  - Aged
MH  - Aged, 80 and over
MH  - Community-Acquired Infections/*epidemiology/mortality
MH  - Comorbidity
MH  - Diabetes Mellitus, Type 2/*epidemiology
MH  - Erythrocyte Transfusion/statistics & numerical data
MH  - Female
MH  - Hospital Mortality/trends
MH  - Hospitalization/*statistics & numerical data
MH  - Humans
MH  - Incidence
MH  - Male
MH  - Middle Aged
MH  - Patient Admission/*statistics & numerical data
MH  - Patient Readmission/statistics & numerical data
MH  - Pneumococcal Infections/*epidemiology
MH  - Pneumonia/*epidemiology/mortality
MH  - Respiration, Artificial/statistics & numerical data
MH  - Retrospective Studies
MH  - Spain/epidemiology
MH  - Staphylococcal Infections/epidemiology
MH  - Staphylococcus aureus/isolation & purification
PMC - PMC5223662
OTO - NOTNLM
OT  - community-acquired pneumonia
OT  - hospitalization
OT  - in-hospitall mortality
OT  - type 2 diabetes
COIS- Conflicts of Interest: None declared.
EDAT- 2017/01/07 06:00
MHDA- 2017/12/16 06:00
PMCR- 2017/01/05
CRDT- 2017/01/07 06:00
PHST- 2017/01/07 06:00 [entrez]
PHST- 2017/01/07 06:00 [pubmed]
PHST- 2017/12/16 06:00 [medline]
PHST- 2017/01/05 00:00 [pmc-release]
AID - bmjopen-2016-013097 [pii]
AID - 10.1136/bmjopen-2016-013097 [doi]
PST - epublish
SO  - BMJ Open. 2017 Jan 5;7(1):e013097. doi: 10.1136/bmjopen-2016-013097.