PMID- 28057983 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20201001 IS - 0974-7796 (Print) IS - 0974-7834 (Electronic) IS - 0974-7796 (Linking) VI - 8 IP - 4 DP - 2016 Oct-Dec TI - Role of extracorporeal shock wave therapy in management of Peyronie's disease: A preliminary report. PG - 409-417 LID - 10.4103/0974-7796.192100 [doi] AB - INTRODUCTION: Peyronie's Disease (PD) is a disease causing psycho social trauma to the patient. Multiple treatment options are available with variable results. Extra Corporeal Shock Wave Therapy (ESWT) is a new insight into the non invasive modality of management. It focuses on the mechanism of inducing angiogenesis in the penile cavernous tissue. MATERIALS AND METHODS: The aim of the study is to determine the role of ESWT in the management of PD. The objectives include demonstrating the improvement in mean International Index of Erectile Function Score (IIEFS), improvement in pain score by Visual Analogue Scale (VAS), change in cavernosal artery flow on colour penile Doppler, reduction in plaque size, and improvement in penile curvature degree after the therapy. 30 patients, between 25-65 years, who were non responders to conservative line of management, were treated with ESWT. The results were evaluated at baseline and 18-24 weeks after the therapy. RESULTS: ESWT significantly improves the cavernosal artery velocity, thereby supporting the theory of angiogenesis. ESWT improves all the domains of IIEF including Erectile Function, Sexual Desire, Sexual Satisfaction, Orgasm and Overall Satisfaction. There is a significant improvement in the pain and penile curvature, and reduction in the plaque size. No adverse effects have been recorded. CONCLUSION: ESWT offers a safe, minimally invasive, OPD based option to the management of the patients of PD in the stable phase of the disease. Patients who do not respond to the conservative line of management can be really benefited by ESWT. FAU - Shimpi, Rajendra Kashinath AU - Shimpi RK AD - Department of Urology and Genito-Urinary Surgery, Ruby Hall Clinic, Pune, Maharashtra, India. FAU - Jain, Ravi Jineshkumar AU - Jain RJ AD - Department of Urology and Genito-Urinary Surgery, Ruby Hall Clinic, Pune, Maharashtra, India. LA - eng PT - Journal Article PL - India TA - Urol Ann JT - Urology annals JID - 101510823 PMC - PMC5100144 OTO - NOTNLM OT - Cavernosal artery velocity OT - International Index of Erectile Function Score OT - Peyronie's disease OT - extracorporeal shock wave therapy OT - plaque OT - visual analogue score EDAT- 2017/01/07 06:00 MHDA- 2017/01/07 06:01 PMCR- 2016/10/01 CRDT- 2017/01/07 06:00 PHST- 2017/01/07 06:00 [entrez] PHST- 2017/01/07 06:00 [pubmed] PHST- 2017/01/07 06:01 [medline] PHST- 2016/10/01 00:00 [pmc-release] AID - UA-8-409 [pii] AID - 10.4103/0974-7796.192100 [doi] PST - ppublish SO - Urol Ann. 2016 Oct-Dec;8(4):409-417. doi: 10.4103/0974-7796.192100.