PMID- 28061987
OWN - NLM
STAT- MEDLINE
DCOM- 20170526
LR  - 20170526
IS  - 1532-8708 (Electronic)
IS  - 0093-7754 (Linking)
VI  - 43
IP  - 6
DP  - 2016 Dec
TI  - Management of multiple myeloma in resource-constrained settings.
PG  - 690-694
LID - S0093-7754(16)30121-X [pii]
LID - 10.1053/j.seminoncol.2016.11.012 [doi]
AB  - The prognosis of patients with multiple myeloma (MM) has improved significantly 
      in the past two decades. This is attributed to use of novel agents for induction, 
      high-dose chemotherapy and autologous stem cell transplantation (ASCT), 
      maintenance therapy, and improved supportive care. Currently, evidence-based 
      management guidelines/recommendations developed by International societies/groups 
      are being followed partially in low-resource settings. Lack of quality 
      diagnostics (eg, cytogenetics/fluorescence in situ hybridization (FISH), serum 
      free light chains), novel therapeutics, and trained manpower, and limited 
      financial resources are key challanges. An optimal utilization of available 
      resources with continued educational activities of treating physicians focused on 
      improving knowledge in the management of such patients may be a way forward to 
      improve the outcome of myeloma patients in these countries. Our current approach 
      to the management of this disease is presented here through a discussion of 
      clinical vignettes.
CI  - Copyright (c) 2016 Elsevier Inc. All rights reserved.
FAU - Kumar, Lalit
AU  - Kumar L
AD  - Department of Medical Oncology, All India Institute of Medical Sciences, New 
      Delhi, India. Electronic address: lalitaiims@yahoo.com.
FAU - Kumar Sahoo, Ranjit
AU  - Kumar Sahoo R
AD  - Department of Medical Oncology, All India Institute of Medical Sciences, New 
      Delhi, India.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20161116
PL  - United States
TA  - Semin Oncol
JT  - Seminars in oncology
JID - 0420432
SB  - IM
MH  - *Health Resources
MH  - Hematopoietic Stem Cell Transplantation
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Multiple Myeloma/*therapy
MH  - Transplantation, Autologous
MH  - Young Adult
OTO - NOTNLM
OT  - Consolidation
OT  - Induction
OT  - Maintenance
OT  - Myeloma
OT  - Transplantation
EDAT- 2017/01/08 06:00
MHDA- 2017/05/27 06:00
CRDT- 2017/01/08 06:00
PHST- 2017/01/08 06:00 [entrez]
PHST- 2017/01/08 06:00 [pubmed]
PHST- 2017/05/27 06:00 [medline]
AID - S0093-7754(16)30121-X [pii]
AID - 10.1053/j.seminoncol.2016.11.012 [doi]
PST - ppublish
SO  - Semin Oncol. 2016 Dec;43(6):690-694. doi: 10.1053/j.seminoncol.2016.11.012. Epub 
      2016 Nov 16.