PMID- 28063768
OWN - NLM
STAT- MEDLINE
DCOM- 20180112
LR  - 20211204
IS  - 1879-3061 (Electronic)
IS  - 1043-2760 (Print)
IS  - 1043-2760 (Linking)
VI  - 28
IP  - 3
DP  - 2017 Mar
TI  - Emerging Role for Mammalian Target of Rapamycin in Male Fertility.
PG  - 165-167
LID - S1043-2760(16)30183-7 [pii]
LID - 10.1016/j.tem.2016.12.004 [doi]
AB  - Male fertility is modulated by environmental, endocrine, paracrine, and metabolic 
      cues. Mammalian target of rapamycin (mTOR) coordinates many cellular events in 
      response to those signals. Here, we discuss how the mTOR pathway integrates and 
      mediates signals throughout the male reproductive system, acting as a central 
      player in the control of spermatogenesis.
CI  - Copyright (c) 2016 Elsevier Ltd. All rights reserved.
FAU - Oliveira, Pedro F
AU  - Oliveira PF
AD  - Department of Microscopy, Laboratory of Cell Biology, Institute of Biomedical 
      Sciences Abel Salazar (ICBAS), University of Porto, Porto, Portugal; Unit for 
      Multidisciplinary Research in Biomedicine (UMIB), Institute of Biomedical 
      Sciences Abel Salazar (ICBAS), University of Porto, Porto, Portugal; Instituto de 
      Investigacao e Inovacao em Saude, University of Porto, Porto, Portugal.
FAU - Cheng, C Y
AU  - Cheng CY
AD  - Population Council's Center for Biomedical Research, New York, USA.
FAU - Alves, Marco G
AU  - Alves MG
AD  - Unit for Multidisciplinary Research in Biomedicine (UMIB), Institute of 
      Biomedical Sciences Abel Salazar (ICBAS), University of Porto, Porto, Portugal; 
      CICS-UBI - Health Sciences Research Centre, University of Beira Interior, 
      Covilha, Portugal. Electronic address: alvesmarc@gmail.com.
LA  - eng
GR  - R01 HD056034/HD/NICHD NIH HHS/United States
GR  - U54 HD029990/HD/NICHD NIH HHS/United States
PT  - Journal Article
PT  - Review
DEP - 20170105
PL  - United States
TA  - Trends Endocrinol Metab
JT  - Trends in endocrinology and metabolism: TEM
JID - 9001516
RN  - EC 2.7.11.1 (TOR Serine-Threonine Kinases)
SB  - IM
MH  - Humans
MH  - Infertility, Male/*metabolism
MH  - Male
MH  - Sertoli Cells/metabolism
MH  - Signal Transduction/genetics/*physiology
MH  - Spermatogenesis/genetics/physiology
MH  - TOR Serine-Threonine Kinases/genetics/*metabolism
PMC - PMC5499664
MID - NIHMS867147
OTO - NOTNLM
OT  - Sertoli cell
OT  - fertility
OT  - mTOR
OT  - spermatogenesis
EDAT- 2017/01/09 06:00
MHDA- 2018/01/13 06:00
PMCR- 2018/03/01
CRDT- 2017/01/09 06:00
PHST- 2016/10/28 00:00 [received]
PHST- 2016/12/15 00:00 [revised]
PHST- 2016/12/15 00:00 [accepted]
PHST- 2017/01/09 06:00 [pubmed]
PHST- 2018/01/13 06:00 [medline]
PHST- 2017/01/09 06:00 [entrez]
PHST- 2018/03/01 00:00 [pmc-release]
AID - S1043-2760(16)30183-7 [pii]
AID - 10.1016/j.tem.2016.12.004 [doi]
PST - ppublish
SO  - Trends Endocrinol Metab. 2017 Mar;28(3):165-167. doi: 10.1016/j.tem.2016.12.004. 
      Epub 2017 Jan 5.