PMID- 28066790
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201001
IS  - 2325-9639 (Print)
IS  - 2325-9639 (Electronic)
IS  - 2325-9639 (Linking)
VI  - 5
IP  - 4
DP  - 2016
TI  - Resistant Hypertension and Sleep Duration among Blacks with Metabolic Syndrome 
      MetSO.
LID - 10.4172/2325-9639.1000183 [doi]
AB  - INTRODUCTION: Resistant hypertension (RHTN) is an important condition affecting 
      29% of the hypertensive population in the U.S., especially among blacks. Sleep 
      disturbances, like obstructive sleep apnea, insomnia, and short sleep duration, 
      are increasingly recognized as underlying modifiable factors for RHTN. We 
      evaluated associations of RHTN with short sleep duration among blacks with 
      metabolic syndrome. METHODS: Data from the Metabolic Syndrome Outcome Study 
      (MetSO), a NIH-funded cohort study characterizing metabolic syndrome (MetS) among 
      blacks were analyzed. MetS was defined according to criteria from the Adult 
      Treatment Panel (ATP III). RHTN was defined according to guidelines from the 
      American Heart Association. Short sleep was defined as self-reported sleep 
      duration <7 hrs experienced during a 24-hour period. RESULTS: Analysis was based 
      on 1,035 patients (mean age: 62+/-14years; female: 69.2%). Of the sample, 90.4% 
      were overweight /obese; 61.4% had diabetes; 74.8% had dyslipidemia; 30.2% had a 
      history of heart disease; and 48% were at high risk for obstructive sleep apnea. 
      Overall, 92.6% reported physician-diagnosed hypertension (HTN) and 20.8% met 
      criteria for RHTN. Analyses showed those with RHTN were more likely to be short 
      sleepers (26.8% vs. 14.9%, p< 0.001). Based on logistic regression analysis, 
      adjusting for effects of age, sex, and medical comorbidities, patients with 
      metabolic syndrome and RHTN had increased odds of being short sleepers (OR = 
      1.95, 95% CI: 1.28-2.97, p = 0.002). CONCLUSION: Among blacks with metabolic 
      syndrome, patients meeting criteria for resistant hypertension showed a twofold 
      greater likelihood of being short sleepers, prompting the need for sleep 
      screening in this vulnerable population.
FAU - Rogers, April
AU  - Rogers A
AD  - Center for Healthful Behavior Change (CHBC), Division of Health and Behavior, 
      Department of Population Health, New York University Medical Center, New York, NY 
      10016, USA.
FAU - Necola, Olivia
AU  - Necola O
AD  - Department of Medicine, Westchester Medical Center, Valhalla, NY 10595, USA.
FAU - Sexias, Azizi
AU  - Sexias A
AD  - Center for Healthful Behavior Change (CHBC), Division of Health and Behavior, 
      Department of Population Health, New York University Medical Center, New York, NY 
      10016, USA.
FAU - Luka, Alla
AU  - Luka A
AD  - Department of Medicine, Division of Endocrinology, State University of New York, 
      Downstate Medical Center, Brooklyn, NY 11203, USA.
FAU - Newsome, Valerie
AU  - Newsome V
AD  - Center for Healthful Behavior Change (CHBC), Division of Health and Behavior, 
      Department of Population Health, New York University Medical Center, New York, NY 
      10016, USA.
FAU - Williams, Stephen
AU  - Williams S
AD  - Center for Healthful Behavior Change (CHBC), Division of Health and Behavior, 
      Department of Population Health, New York University Medical Center, New York, NY 
      10016, USA.
FAU - McFarlane, Samy I
AU  - McFarlane SI
AD  - Department of Medicine, Division of Endocrinology, State University of New York, 
      Downstate Medical Center, Brooklyn, NY 11203, USA.
FAU - Jean-Louis, Girardin
AU  - Jean-Louis G
AD  - Center for Healthful Behavior Change (CHBC), Division of Health and Behavior, 
      Department of Population Health, New York University Medical Center, New York, NY 
      10016, USA.
LA  - eng
GR  - K01 HL135452/HL/NHLBI NIH HHS/United States
GR  - R01 HL095799/HL/NHLBI NIH HHS/United States
GR  - R01 MD004113/MD/NIMHD NIH HHS/United States
GR  - R25 HL105444/HL/NHLBI NIH HHS/United States
PT  - Journal Article
DEP - 20160812
PL  - United States
TA  - J Sleep Disord Treat Care
JT  - Journal of sleep disorders-- treatment & care
JID - 101621586
PMC - PMC5214926
MID - NIHMS837878
OTO - NOTNLM
OT  - Metabolic syndrome
OT  - Resistant hypertension
OT  - Sleep duration
EDAT- 2017/01/10 06:00
MHDA- 2017/01/10 06:01
PMCR- 2017/01/05
CRDT- 2017/01/10 06:00
PHST- 2017/01/10 06:00 [entrez]
PHST- 2017/01/10 06:00 [pubmed]
PHST- 2017/01/10 06:01 [medline]
PHST- 2017/01/05 00:00 [pmc-release]
AID - 10.4172/2325-9639.1000183 [doi]
PST - ppublish
SO  - J Sleep Disord Treat Care. 2016;5(4):10.4172/2325-9639.1000183. doi: 
      10.4172/2325-9639.1000183. Epub 2016 Aug 12.