PMID- 28067973
OWN - NLM
STAT- MEDLINE
DCOM- 20180522
LR  - 20181127
IS  - 1522-2586 (Electronic)
IS  - 1053-1807 (Linking)
VI  - 46
IP  - 3
DP  - 2017 Sep
TI  - Simultaneous multislice readout-segmented echo planar imaging for accelerated 
      diffusion tensor imaging of the mandibular nerve: A feasibility study.
PG  - 663-677
LID - 10.1002/jmri.25603 [doi]
AB  - PURPOSE: To assess the feasibility of diffusion tensor imaging (DTI) using 
      simultaneous multislice (SMS) acquisition with blipped controlled aliasing in 
      parallel imaging (CAIPI) for accelerated readout-segmented echo planar imaging 
      (rs-EPI) of the mandibular nerves. DTI of the mandibular nerves using EPI is 
      challenging due to susceptibility artifacts. Rs-EPI is less prone to artifacts 
      but associated with longer scan durations. MATERIALS AND METHODS: Eight 
      asymptomatic volunteers were imaged at 3T using a 64-channel head/neck coil. 
      Conventional, 2-fold (2xSMS) and 3-fold (3xSMS) slice-accelerated rs-EPI 
      sequences were acquired. Tractography of the mandibular nerves was performed. 
      Signal-to-noise ratio (SNR), fractional anisotropy (FA), mean diffusivity (MD), 
      and number of tracts were calculated. Artifacts were evaluated qualitatively on 
      Likert scales. Parameters were compared statistically. Clinical feasibility of 
      2xSMS rs-EPI was tested in four patients. RESULTS: SNR was similar for 
      conventional (mean +/- SD; 8.55 +/- 3.90) and 2xSMS rs-EPI (7.83 +/- 3.15) but lower 
      for 3xSMS rs-EPI (5.42 +/- 2.93; analysis of variance, P = 0.004). FA was similar 
      for all sequences (rs-EPI, 0.42 +/- 0.08; 2xSMS rs-EPI, 0.43 +/- 0.08; 3xSMS rs-EPI, 
      0.44 +/- 0.06), while 3xSMS rs-EPI showed lower MD (rs-EPI, 0.0015 +/- 0.0003; 2xSMS 
      rs-EPI, 0.0014 +/- 0.0001; 3xSMS rs-EPI, 0.0013 +/- 0.0003) and lower number of 
      tracts (rs-EPI, 66.56 +/- 51.31; 2xSMS rs-EPI, 65.75 +/- 55.40; 3xSMS rs-EPI, 
      37.93 +/- 52.42) compared to rs-EPI and 2xSMS rs-EPI. Additionally, 2xSMS rs-EPI 
      was feasible in four clinical patients and provided robust imaging results. 
      CONCLUSION: 2xSMS rs-EPI yielded similar SNR, FA, and MD values compared to 
      conventional rs-EPI at reduced scan time and is feasible in clinical patients. 
      These findings suggest the potential clinical applicability of rs-EPI for DTI of 
      the mandibular nerve. LEVEL OF EVIDENCE: 2 Technical Efficacy: Stage 1 J. MAGN. 
      RESON. IMAGING 2017;46:663-677.
CI  - (c) 2017 International Society for Magnetic Resonance in Medicine.
FAU - Manoliu, Andrei
AU  - Manoliu A
AD  - Institute for Diagnostic and Interventional Radiology, Department of Radiology, 
      University Hospital Zurich, University of Zurich, Zurich, Switzerland.
AD  - Psychiatric University Hospital, Department of Psychiatry, Psychotherapy and 
      Psychosomatics, University of Zurich, Zurich, Switzerland.
FAU - Ho, Michael
AU  - Ho M
AD  - Institute for Diagnostic and Interventional Radiology, Department of Radiology, 
      University Hospital Zurich, University of Zurich, Zurich, Switzerland.
FAU - Piccirelli, Marco
AU  - Piccirelli M
AD  - Department of Neuroradiology, University Hospital Zurich, University of Zurich, 
      Zurich, Switzerland.
FAU - Nanz, Daniel
AU  - Nanz D
AD  - Institute for Diagnostic and Interventional Radiology, Department of Radiology, 
      University Hospital Zurich, University of Zurich, Zurich, Switzerland.
FAU - Filli, Lukas
AU  - Filli L
AUID- ORCID: 0000-0003-0574-5127
AD  - Institute for Diagnostic and Interventional Radiology, Department of Radiology, 
      University Hospital Zurich, University of Zurich, Zurich, Switzerland.
FAU - Dappa, Evelyn
AU  - Dappa E
AD  - Institute for Diagnostic and Interventional Radiology, Department of Radiology, 
      University Hospital Zurich, University of Zurich, Zurich, Switzerland.
FAU - Liu, Wei
AU  - Liu W
AD  - Siemens Shenzhen Magnetic Resonance Ltd, Shenzhen, China.
FAU - Ettlin, Dominik A
AU  - Ettlin DA
AD  - Center of Dental Medicine, University of Zurich, Zurich, Switzerland.
FAU - Boss, Andreas
AU  - Boss A
AD  - Institute for Diagnostic and Interventional Radiology, Department of Radiology, 
      University Hospital Zurich, University of Zurich, Zurich, Switzerland.
FAU - Andreisek, Gustav
AU  - Andreisek G
AD  - Institute for Diagnostic and Interventional Radiology, Department of Radiology, 
      University Hospital Zurich, University of Zurich, Zurich, Switzerland.
FAU - Kuhn, Felix P
AU  - Kuhn FP
AD  - Institute for Diagnostic and Interventional Radiology, Department of Radiology, 
      University Hospital Zurich, University of Zurich, Zurich, Switzerland.
LA  - eng
PT  - Journal Article
DEP - 20170109
PL  - United States
TA  - J Magn Reson Imaging
JT  - Journal of magnetic resonance imaging : JMRI
JID - 9105850
SB  - IM
MH  - Adult
MH  - Diffusion Tensor Imaging/*methods
MH  - Echo-Planar Imaging/*methods
MH  - Feasibility Studies
MH  - Female
MH  - Humans
MH  - Image Processing, Computer-Assisted/*methods
MH  - Male
MH  - Mandibular Nerve/*diagnostic imaging
MH  - Middle Aged
MH  - Reproducibility of Results
MH  - Young Adult
OTO - NOTNLM
OT  - diffusion tensor imaging
OT  - diffusion tractography
OT  - mandibular nerve
OT  - simultaneous multislice echo-planar imaging
EDAT- 2017/01/10 06:00
MHDA- 2018/05/23 06:00
CRDT- 2017/01/10 06:00
PHST- 2016/05/22 00:00 [received]
PHST- 2016/12/05 00:00 [accepted]
PHST- 2017/01/10 06:00 [pubmed]
PHST- 2018/05/23 06:00 [medline]
PHST- 2017/01/10 06:00 [entrez]
AID - 10.1002/jmri.25603 [doi]
PST - ppublish
SO  - J Magn Reson Imaging. 2017 Sep;46(3):663-677. doi: 10.1002/jmri.25603. Epub 2017 
      Jan 9.