PMID- 28072584
OWN - NLM
STAT- MEDLINE
DCOM- 20171024
LR  - 20181202
IS  - 1361-6560 (Electronic)
IS  - 0031-9155 (Linking)
VI  - 62
IP  - 4
DP  - 2017 Feb 21
TI  - Verification of respiratory-gated radiotherapy with new real-time tumour-tracking 
      radiotherapy system using cine EPID images and a log file.
PG  - 1585-1599
LID - 10.1088/1361-6560/aa587d [doi]
AB  - A combined system comprising the TrueBeam linear accelerator and a new real-time 
      tumour-tracking radiotherapy system, SyncTraX, was installed at our institution. 
      The objectives of this study are to develop a method for the verification of 
      respiratory-gated radiotherapy with SyncTraX using cine electronic portal image 
      device (EPID) images and a log file and to verify this treatment in clinical 
      cases. Respiratory-gated radiotherapy was performed using TrueBeam and the 
      SyncTraX system. Cine EPID images and a log file were acquired for a phantom and 
      three patients during the course of the treatment. Digitally reconstructed 
      radiographs (DRRs) were created for each treatment beam using a planning CT set. 
      The cine EPID images, log file, and DRRs were analysed using a developed 
      software. For the phantom case, the accuracy of the proposed method was evaluated 
      to verify the respiratory-gated radiotherapy. For the clinical cases, the intra- 
      and inter-fractional variations of the fiducial marker used as an internal 
      surrogate were calculated to evaluate the gating accuracy and set-up uncertainty 
      in the superior-inferior (SI), anterior-posterior (AP), and left-right (LR) 
      directions. The proposed method achieved high accuracy for the phantom 
      verification. For the clinical cases, the intra- and inter-fractional variations 
      of the fiducial marker were  ⩽3 mm and  +/-3 mm in the SI, AP, and LR directions. 
      We proposed a method for the verification of respiratory-gated radiotherapy with 
      SyncTraX using cine EPID images and a log file and showed that this treatment is 
      performed with high accuracy in clinical cases.
FAU - Shiinoki, Takehiro
AU  - Shiinoki T
AD  - Department of Radiation Oncology, Graduate School of Medicine, Yamaguchi 
      University, 1-1-1 Minamikogushi, Yamaguchi 755-8535, Japan.
FAU - Hanazawa, Hideki
AU  - Hanazawa H
FAU - Yuasa, Yuki
AU  - Yuasa Y
FAU - Fujimoto, Koya
AU  - Fujimoto K
FAU - Uehara, Takuya
AU  - Uehara T
FAU - Shibuya, Keiko
AU  - Shibuya K
LA  - eng
PT  - Journal Article
DEP - 20170110
PL  - England
TA  - Phys Med Biol
JT  - Physics in medicine and biology
JID - 0401220
SB  - IM
MH  - *Computer Systems
MH  - Fiducial Markers
MH  - Humans
MH  - Neoplasms/diagnostic imaging/radiotherapy
MH  - Phantoms, Imaging
MH  - Radiotherapy Planning, Computer-Assisted/instrumentation/*methods/standards
MH  - Respiratory-Gated Imaging Techniques/instrumentation/*methods/standards
MH  - Software
MH  - Tomography, X-Ray Computed/instrumentation/*methods/standards
EDAT- 2017/01/11 06:00
MHDA- 2017/10/25 06:00
CRDT- 2017/01/11 06:00
PHST- 2017/01/11 06:00 [pubmed]
PHST- 2017/10/25 06:00 [medline]
PHST- 2017/01/11 06:00 [entrez]
AID - 10.1088/1361-6560/aa587d [doi]
PST - ppublish
SO  - Phys Med Biol. 2017 Feb 21;62(4):1585-1599. doi: 10.1088/1361-6560/aa587d. Epub 
      2017 Jan 10.