PMID- 28077366
OWN - NLM
STAT- MEDLINE
DCOM- 20170818
LR  - 20220321
IS  - 1759-9873 (Electronic)
IS  - 0964-5284 (Linking)
VI  - 35
IP  - 3
DP  - 2017 Jun
TI  - Effectiveness of acupuncture in women with polycystic ovarian syndrome undergoing 
      in vitro fertilisation or intracytoplasmic sperm injection: a systematic review 
      and meta-analysis.
PG  - 162-170
LID - 10.1136/acupmed-2016-011163 [doi]
AB  - OBJECTIVES: The aim of this systematic review was to assess the evidence from 
      randomised controlled trials (RCTs) on the efficacy, effectiveness and safety of 
      acupuncture in women with polycystic ovarian syndrome (PCOS) undergoing in vitro 
      fertilisation (IVF) or intracytoplasmic sperm injection (ICSI). METHODS: We 
      searched a total of 15 databases through October 2015. The participants were 
      women with PCOS (diagnosed using the Rotterdam criteria) undergoing IVF or ICSI. 
      Eligible trials were those with intervention groups receiving manual acupuncture 
      (MA) or electroacupuncture (EA), and control groups receiving sham acupuncture, 
      no treatment or other treatments. Outcomes included the clinical pregnancy rate 
      (CPR), live birth rate (LBR), ongoing pregnancy rate (OPR) and incidence of 
      ovarian hyperstimulation syndrome (OHSS) and adverse events (AEs). For 
      statistical pooling, the risk ratio (RR) and its 95% (confidence interval) CI was 
      calculated using a random effects model. RESULTS: Four RCTs including 430 
      participants were selected. All trials compared acupuncture (MA/EA) against no 
      treatment. Acupuncture significantly increased the CPR (RR 1.33, 95% CI 1.03 to 
      1.71) and OPR (RR 2.03, 95% CI 1.08 to 3.81) and decreased the risk of OHSS (RR 
      0.63, 95% CI 0.42 to 0.94); however, there was no significant difference in the 
      LBR (RR 1.61, 95% CI 0.73 to 3.58). None of the RCTs reported on AEs. 
      CONCLUSIONS: Acupuncture may increase the CPR and OPR and decrease the risk of 
      OHSS in women with PCOS undergoing IVF or ICSI. Further studies are needed to 
      confirm the efficacy and safety of acupuncture as an adjunct to assisted 
      reproductive technology in this particular population.
CI  - Published by the BMJ Publishing Group Limited. For permission to use (where not 
      already granted under a licence) please go to 
      http://www.bmj.com/company/products-services/rights-and-licensing/.
FAU - Jo, Junyoung
AU  - Jo J
AUID- ORCID: 0000-0001-9721-7641
AD  - Department of Korean Gynecology, Conmaul Hospital of Korean Medicine, Seoul, 
      Republic of Korea.
FAU - Lee, Yoon Jae
AU  - Lee YJ
AD  - Department of Korean Gynecology, Jaseng Hospital of Korean Medicine, Seoul, 
      Republic of Korea.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Review
PT  - Systematic Review
DEP - 20170111
PL  - England
TA  - Acupunct Med
JT  - Acupuncture in medicine : journal of the British Medical Acupuncture Society
JID - 9304117
SB  - IM
MH  - *Acupuncture Therapy
MH  - Female
MH  - Fertilization in Vitro
MH  - Humans
MH  - Polycystic Ovary Syndrome/physiopathology/*therapy
MH  - Pregnancy
MH  - Pregnancy Rate
MH  - Randomized Controlled Trials as Topic
MH  - Sperm Injections, Intracytoplasmic
OTO - NOTNLM
OT  - ACUPUNCTURE
OT  - GYNAECOLOGY
COIS- Competing interests: None declared.
EDAT- 2017/01/13 06:00
MHDA- 2017/08/19 06:00
CRDT- 2017/01/13 06:00
PHST- 2016/12/20 00:00 [accepted]
PHST- 2017/01/13 06:00 [pubmed]
PHST- 2017/08/19 06:00 [medline]
PHST- 2017/01/13 06:00 [entrez]
AID - acupmed-2016-011163 [pii]
AID - 10.1136/acupmed-2016-011163 [doi]
PST - ppublish
SO  - Acupunct Med. 2017 Jun;35(3):162-170. doi: 10.1136/acupmed-2016-011163. Epub 2017 
      Jan 11.