PMID- 28088050
OWN - NLM
STAT- MEDLINE
DCOM- 20170816
LR  - 20181202
IS  - 1525-5069 (Electronic)
IS  - 1525-5050 (Linking)
VI  - 67
DP  - 2017 Feb
TI  - Pharmacists' knowledge of issues in pharmacotherapy of epilepsy using 
      antiepileptic drugs: A cross-sectional study in Palestinian pharmacy practice.
PG  - 39-44
LID - S1525-5050(16)30602-3 [pii]
LID - 10.1016/j.yebeh.2016.11.027 [doi]
AB  - OBJECTIVE: Antiepileptic drugs (AEDs) are mainstay in controlling epileptic 
      seizures. As experts in medications, pharmacists should be able to ensure 
      accuracy of dosing regimens, explain adverse effects, and screen for and alert 
      people with epilepsy (PWE) and their physicians to possible drug-drug 
      interactions (DDIs). The aim of this study was to evaluate pharmacists' knowledge 
      of issues in pharmacotherapy of epilepsy using AEDs. METHODS: This was a 
      cross-sectional observational study conducted in the Palestinian pharmacy 
      practice. A 10-item case-based questionnaire was used to determine actions taken 
      by pharmacists in theoretical situations in pharmacotherapy of epilepsy. 
      Demographic and practice details of the study participants were also collected. 
      Scores were calculated as percentage of correct answers for each participant. 
      RESULTS: The number of participants was 394. The majority (approximately 75%) 
      identified themselves as community pharmacists. The median score was 33.4% with 
      an IQR of 33.3. Pharmacists who received training on epilepsy and AEDs during 
      their pharmacy degree program were 4.78-fold (95% C.I. of 1.82-12.60) more likely 
      to score >/=50% in the test than those who did not receive training on epilepsy and 
      AEDs. Despite gaps in knowledge, pharmacists tended to perform the necessary 
      action in cases of adverse effects and aggravated seizures associated with AEDs. 
      CONCLUSION: Pharmacists can play a crucial role in providing essential 
      information on AEDs to patients and prescribers. There are many knowledge gaps 
      that need to be filled. Specifically designed pedagogic and/or training 
      interventions might be helpful in filling these gaps.
CI  - Copyright (c) 2016 Elsevier Inc. All rights reserved.
FAU - Shawahna, Ramzi
AU  - Shawahna R
AD  - Department of Physiology, Pharmacology and Toxicology, Faculty of Medicine and 
      Health Sciences, An-Najah National University, Nablus, Palestine; An-Najah 
      BioSciences Unit, Centre for Poisons Control, Chemical and Biological Analyses, 
      An-Najah National University, Nablus, Palestine; Department of Pharmacy, Faculty 
      of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine. 
      Electronic address: ramzi_shawahna@hotmail.com.
FAU - Atrash, Ahlam
AU  - Atrash A
AD  - Department of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah 
      National University, Nablus, Palestine.
FAU - Jebril, Aman
AU  - Jebril A
AD  - Department of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah 
      National University, Nablus, Palestine.
FAU - Khalaf, Areen
AU  - Khalaf A
AD  - Department of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah 
      National University, Nablus, Palestine.
FAU - Shaheen, Eman
AU  - Shaheen E
AD  - Department of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah 
      National University, Nablus, Palestine.
FAU - Tahboosh, Hala
AU  - Tahboosh H
AD  - Department of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah 
      National University, Nablus, Palestine.
LA  - eng
PT  - Journal Article
PT  - Observational Study
DEP - 20170112
PL  - United States
TA  - Epilepsy Behav
JT  - Epilepsy & behavior : E&B
JID - 100892858
RN  - 0 (Anticonvulsants)
SB  - IM
MH  - Adult
MH  - Anticonvulsants/*therapeutic use
MH  - *Arabs
MH  - Cross-Sectional Studies
MH  - Drug Interactions
MH  - Epilepsy/*drug therapy/epidemiology
MH  - Female
MH  - *Health Knowledge, Attitudes, Practice
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Pharmacies/*standards
MH  - Pharmacists/*standards
MH  - Professional Role
MH  - Surveys and Questionnaires
OTO - NOTNLM
OT  - Antiepileptic drugs
OT  - Epilepsy
OT  - Knowledge
OT  - Palestine
OT  - People with epilepsy
OT  - Pharmacists
EDAT- 2017/01/15 06:00
MHDA- 2017/08/17 06:00
CRDT- 2017/01/15 06:00
PHST- 2016/10/21 00:00 [received]
PHST- 2016/11/16 00:00 [revised]
PHST- 2016/11/17 00:00 [accepted]
PHST- 2017/01/15 06:00 [pubmed]
PHST- 2017/08/17 06:00 [medline]
PHST- 2017/01/15 06:00 [entrez]
AID - S1525-5050(16)30602-3 [pii]
AID - 10.1016/j.yebeh.2016.11.027 [doi]
PST - ppublish
SO  - Epilepsy Behav. 2017 Feb;67:39-44. doi: 10.1016/j.yebeh.2016.11.027. Epub 2017 
      Jan 12.