PMID- 28093206
OWN - NLM
STAT- MEDLINE
DCOM- 20170501
LR  - 20181202
IS  - 1873-3778 (Electronic)
IS  - 0021-9673 (Linking)
VI  - 1485
DP  - 2017 Feb 17
TI  - Urea-formaldehyde monolithic column for hydrophilic in-tube solid-phase 
      microextraction of aminoglycosides.
PG  - 24-31
LID - S0021-9673(17)30073-0 [pii]
LID - 10.1016/j.chroma.2017.01.027 [doi]
AB  - A novel urea-formaldehyde (UF) monolithic column has been developed and exploited 
      as a sorbent for hydrophilic in-tube solid-phase microextraction (in-tube SPME) 
      of aminoglycosides (AGs). Because of the innate hydrophilicity, UF monolith 
      showed high extraction efficiency towards these hydrophilic analytes. The 
      adsorption capacities for target compounds dissolved in water/ACN (1:1, v/v) were 
      in the range of 5.18-7.36mug/cm. Due to the lack of a chromophore, evaporative 
      light scattering detector (ELSD) was selected as the detector for AGs, and 
      coupled with the online in-tube SPME-HPLC system. Several factors of the online 
      system, such as trifluoroacetic acid (TFA) and ACN percentage in the sampling 
      solution, ionic strength in the sample solution, elution volume, sampling and 
      elution flow rate, were optimized with respect to the extraction efficiencies. 
      Under the optimized conditions, the limits of detection (LODs) of streptomycin, 
      tobramycin and neomycin were discovered in the range of 3.0-5.2mug/kg. The 
      recoveries were ranged from 82.1 to 96.7% with relative standard deviations 
      (RSDs) of 2.3-5.1% (n=4) at spiking levels of 50, 200 and 500mug/kg, respectively. 
      The excellent applicability of the UF monolithic column was examined by the 
      determination of streptomycin in practical tilapia samples, which showed the 
      potential advantages for the analysis of polar analytes in complicated samples.
CI  - Copyright (c) 2017 Elsevier B.V. All rights reserved.
FAU - Wang, Jiabin
AU  - Wang J
AD  - Institute of Biomedical and Pharmaceutical Technology, Fuzhou University, Fuzhou, 
      350002, China. Electronic address: jbwang@fzu.edu.cn.
FAU - Zhao, Qi
AU  - Zhao Q
AD  - Institute of Biomedical and Pharmaceutical Technology, Fuzhou University, Fuzhou, 
      350002, China.
FAU - Jiang, Nan
AU  - Jiang N
AD  - Institute of Biomedical and Pharmaceutical Technology, Fuzhou University, Fuzhou, 
      350002, China.
FAU - Li, Wenbang
AU  - Li W
AD  - Institute of Biomedical and Pharmaceutical Technology, Fuzhou University, Fuzhou, 
      350002, China.
FAU - Chen, Li
AU  - Chen L
AD  - Institute of Biomedical and Pharmaceutical Technology, Fuzhou University, Fuzhou, 
      350002, China.
FAU - Lin, Xucong
AU  - Lin X
AD  - Institute of Food Safety and Environment Monitoring, Fuzhou University, Fuzhou, 
      350108, China.
FAU - Xie, Zenghong
AU  - Xie Z
AD  - Institute of Food Safety and Environment Monitoring, Fuzhou University, Fuzhou, 
      350108, China.
FAU - You, Lijun
AU  - You L
AD  - Institute of Biomedical and Pharmaceutical Technology, Fuzhou University, Fuzhou, 
      350002, China.
FAU - Zhang, Qiqing
AU  - Zhang Q
AD  - Institute of Biomedical and Pharmaceutical Technology, Fuzhou University, Fuzhou, 
      350002, China; Key Laboratory of Biomedical Material of Tianjin, Institute of 
      Biomedical Engineering, Chinese Academy of Medical Science & Peking Union Medical 
      College, Tianjin 300192, China. Electronic address: zhangqiq@126.com.
LA  - eng
PT  - Journal Article
DEP - 20170110
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Aminoglycosides)
RN  - 0 (Anti-Bacterial Agents)
RN  - 0 (Polymers)
RN  - 059QF0KO0R (Water)
RN  - I16QD7X297 (Neomycin)
RN  - VZ8RRZ51VK (Tobramycin)
RN  - Y45QSO73OB (Streptomycin)
SB  - IM
MH  - Adsorption
MH  - Aminoglycosides/*isolation & purification
MH  - Animals
MH  - Anti-Bacterial Agents/*isolation & purification
MH  - Chromatography, High Pressure Liquid
MH  - Hydrophobic and Hydrophilic Interactions
MH  - Limit of Detection
MH  - Neomycin/isolation & purification
MH  - Polymers/chemical synthesis
MH  - Solid Phase Microextraction/instrumentation/*methods
MH  - Streptomycin/isolation & purification
MH  - Tilapia
MH  - Tobramycin/isolation & purification
MH  - Water
OTO - NOTNLM
OT  - Aminoglycosides
OT  - Evaporative light scattering detector
OT  - Hydrophilic interaction
OT  - In-tube solid-phase microextraction
OT  - Urea-formaldehyde monolithic column
EDAT- 2017/01/18 06:00
MHDA- 2017/05/02 06:00
CRDT- 2017/01/18 06:00
PHST- 2016/11/04 00:00 [received]
PHST- 2017/01/09 00:00 [revised]
PHST- 2017/01/09 00:00 [accepted]
PHST- 2017/01/18 06:00 [pubmed]
PHST- 2017/05/02 06:00 [medline]
PHST- 2017/01/18 06:00 [entrez]
AID - S0021-9673(17)30073-0 [pii]
AID - 10.1016/j.chroma.2017.01.027 [doi]
PST - ppublish
SO  - J Chromatogr A. 2017 Feb 17;1485:24-31. doi: 10.1016/j.chroma.2017.01.027. Epub 
      2017 Jan 10.