PMID- 28100576
OWN - NLM
STAT- MEDLINE
DCOM- 20170306
LR  - 20200225
IS  - 1757-790X (Electronic)
IS  - 1757-790X (Linking)
VI  - 2017
DP  - 2017 Jan 18
TI  - Perioperative management of a large, late presenting phaeochromocytoma.
LID - 10.1136/bcr-2016-218126 [doi]
LID - bcr2016218126
AB  - A 77-year-old man presenting to the emergency department with an acute coronary 
      syndrome was later found to have a phaeochromocytoma. The lateness of this 
      presentation was likely due to the protective alpha blocking effects of long-term 
      terazosin therapy for his prostatism. alpha blockers such as terazosin are a 
      well-recognised medical therapy in the perioperative optimisation of 
      phaeochromocytoma because they treat the adrenergic effects of catecholamine 
      release from the tumour such as hypertension. This patient was diagnosed with an 
      ST elevation myocardial infarction (STEMI). A cardiac angiogram showed no 
      evidence of vessel occlusion. A right adrenal mass of 9x8x9 cm was incidentally 
      found and confirmed as a phaeochromocytoma with raised plasma metanephrines and 
      normetanephrines. Following preoperative optimisation and multidisciplinary team 
      involvement, an open right adrenalectomy was performed successfully some months 
      later.
CI  - 2017 BMJ Publishing Group Ltd.
FAU - Macrosson, Duncan
AU  - Macrosson D
AD  - North Shore Hospital, Auckland, New Zealand.
FAU - Love, Andrew
AU  - Love A
AD  - North Shore Hospital, Auckland, New Zealand.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20170118
PL  - England
TA  - BMJ Case Rep
JT  - BMJ case reports
JID - 101526291
RN  - 0 (Adrenergic alpha-Antagonists)
RN  - 0TTZ664R7Z (Phenoxybenzamine)
SB  - IM
MH  - Adrenal Gland Neoplasms/complications/diagnostic imaging/*therapy
MH  - *Adrenalectomy
MH  - Adrenergic alpha-Antagonists/*therapeutic use
MH  - Aged
MH  - Coronary Angiography
MH  - Electrocardiography
MH  - Humans
MH  - Male
MH  - *Perioperative Care
MH  - Phenoxybenzamine/*therapeutic use
MH  - Pheochromocytoma/complications/diagnostic imaging/*therapy
MH  - ST Elevation Myocardial Infarction/*diagnosis/etiology
MH  - Tomography, X-Ray Computed
PMC - PMC5256594
COIS- Conflicts of Interest: None declared.
EDAT- 2017/01/20 06:00
MHDA- 2017/03/07 06:00
PMCR- 2019/01/18
CRDT- 2017/01/20 06:00
PHST- 2017/01/20 06:00 [entrez]
PHST- 2017/01/20 06:00 [pubmed]
PHST- 2017/03/07 06:00 [medline]
PHST- 2019/01/18 00:00 [pmc-release]
AID - bcr-2016-218126 [pii]
AID - 10.1136/bcr-2016-218126 [doi]
PST - epublish
SO  - BMJ Case Rep. 2017 Jan 18;2017:bcr2016218126. doi: 10.1136/bcr-2016-218126.