PMID- 28100577
OWN - NLM
STAT- MEDLINE
DCOM- 20170306
LR  - 20200225
IS  - 1757-790X (Electronic)
IS  - 1757-790X (Linking)
VI  - 2017
DP  - 2017 Jan 18
TI  - Late spontaneous decapsulation of the kidney graft in a patient with hepatitis C 
      and treated with sirolimus: possible pathophysiological association in a rare 
      complication.
LID - 10.1136/bcr-2016-218335 [doi]
LID - bcr2016218335
AB  - Late decapsulation with fluid collection is a rare complication of renal 
      transplantation with deleterious effects on kidney function. Its physiopathology 
      is unclear but there might be an association with mammalian target of rapamycin 
      (m-TOR) inhibitors, especially in patients with chronic hepatitis C. We report a 
      case of late spontaneous decapsulation 12 years after kidney transplant in a 
      patient infected with hepatitis C under treatment with sirolimus. He underwent 
      marsupialisation of the collection, sirolimus was converted to cyclosporine and 
      hepatitis C treatment was performed with success. This is the first successful 
      case report of late spontaneous decapsulation of the kidney graft in a patient 
      with hepatitis C.
CI  - 2017 BMJ Publishing Group Ltd.
FAU - Leal, Rita
AU  - Leal R
AD  - Department of Nephrology, Centro Hospitalar e Universitario de Coimbra, Coimbra, 
      Portugal.
FAU - Pinto, Helena
AU  - Pinto H
AD  - Centro Hospitalar e Universitario de Coimbra, Coimbra, Portugal.
FAU - Alves, Rui
AU  - Alves R
AD  - Department of Nephrology, Centro Hospitalar e Universitario de Coimbra, Coimbra, 
      Portugal.
AD  - Universidade de Coimbra Faculdade de Medicina, Coimbra, Portugal.
FAU - Figueiredo, Arnaldo
AU  - Figueiredo A
AD  - Universidade de Coimbra Faculdade de Medicina, Coimbra, Portugal.
AD  - Department of Urology and Kidney Transplantation, Centro Hospitalar e 
      Universitario de Coimbra, Coimbra, Portugal.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20170118
PL  - England
TA  - BMJ Case Rep
JT  - BMJ case reports
JID - 101526291
RN  - 0 (Antiviral Agents)
RN  - 0 (Immunosuppressive Agents)
RN  - 83HN0GTJ6D (Cyclosporine)
RN  - 9PHQ9Y1OLM (Prednisolone)
RN  - W36ZG6FT64 (Sirolimus)
SB  - IM
MH  - Antiviral Agents/therapeutic use
MH  - Cyclosporine/therapeutic use
MH  - Drug Substitution
MH  - Graft Rejection/*prevention & control
MH  - Hepatitis C, Chronic/*complications/drug therapy
MH  - Humans
MH  - Immunosuppressive Agents/*therapeutic use
MH  - Kidney Diseases/complications/*diagnostic imaging
MH  - *Kidney Transplantation
MH  - Male
MH  - Middle Aged
MH  - Postoperative Complications/*diagnostic imaging
MH  - Prednisolone/therapeutic use
MH  - Risk Factors
MH  - Sirolimus/*therapeutic use
MH  - Tomography, X-Ray Computed
PMC - PMC5256561
COIS- Conflicts of Interest: None declared.
EDAT- 2017/01/20 06:00
MHDA- 2017/03/07 06:00
PMCR- 2019/01/18
CRDT- 2017/01/20 06:00
PHST- 2017/01/20 06:00 [entrez]
PHST- 2017/01/20 06:00 [pubmed]
PHST- 2017/03/07 06:00 [medline]
PHST- 2019/01/18 00:00 [pmc-release]
AID - bcr-2016-218335 [pii]
AID - 10.1136/bcr-2016-218335 [doi]
PST - epublish
SO  - BMJ Case Rep. 2017 Jan 18;2017:bcr2016218335. doi: 10.1136/bcr-2016-218335.