PMID- 28101114
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201001
IS  - 1735-8949 (Print)
IS  - 1735-9392 (Electronic)
IS  - 1735-9392 (Linking)
VI  - 10
IP  - 3
DP  - 2016 Sep
TI  - Dietary and Socio-Demographic Determinants of Serum Persistent Organic Pollutants 
      (POPs) Levels in Pregnant Women in Tehran.
PG  - 129-138
AB  - Objective: To determine the levels of Polychlorinated biphenyls (PCBs) and 
      Polybrominateddiphenyl ethers (PBDEs) as persistent organic pollutants (POPs) in 
      serum of primiparous women at the third trimester of pregnancy and identify the 
      main determinants of POPs levels such as socio-demographic, lifestyle, and diet 
      in Tehran. Materials and methods: One- hundred eighty five serum samples from two 
      simultaneous case-control studies were collected from September 2013 until August 
      2015.Ten most abundant PCB congeners (International Union of Pure and Applied 
      Chemistry (IUPAC) congeners 28, 52, 74, 99, 101, 118, 138, 153, 180 and 187) as 
      well as eight PBDE congeners (IUPAC congeners 28, 47, 99, 100, 153, 154, 183 and 
      209)were analyzed by Gas Chromatography Mass Spectrometry (GC/MS). Multiple 
      linear regression analysis was conducted to explain the relationship between 
      total PCBs and total BPDEs and most detected congeners and some determinants, 
      separately. Results: The mean (SD) age of the participating women was 27.82 +/- 
      5.24 years. The geometric mean (SD) of total PCBs was 2.42 +/- 2.26 and total PBDEs 
      was 1.28 +/- 1.41 ng/g lipid. Only the PCB 138, PCB 153 and PBDE 153 were detected 
      in 100% of samples. We observed a significant relationship between the time of 
      being indoors and total PBDEs (P = 0.03). Passive smoking was significantly 
      associated with PCB 153 (P = 0.049). The results of the linear regression 
      analysis showed the negative and weak association (P-value < 0.05) between diet 
      (egg and fat and oil consumption) and POPs in this population. Conclusion: It 
      seems the most common route of exposure to PBDEs in our population is indoor 
      pollutants. Meanwhile inhalation of smoke from environment is a route of exposure 
      to PCB 153. Further study is needed to evaluate the effects of socio-demographics 
      and especially dietary intake on POPs level.
FAU - Eslami, Bita
AU  - Eslami B
AD  - Vali-e-Asr Reproductive Health Research Center, Tehran University of Medical 
      Sciences, Tehran, Iran.
FAU - Hossein-Rashidi, Batool
AU  - Hossein-Rashidi B
AD  - Vali-e-Asr Reproductive Health Research Center, Tehran University of Medical 
      Sciences, Tehran, Iran.
FAU - Naddafi, Kazem
AU  - Naddafi K
AD  - Center for Air Pollution Research (CAPR), Institute for Environmental Research 
      (IER), Tehran University of Medical Sciences, Tehran, Iran.
FAU - Rastkari, Noushin
AU  - Rastkari N
AD  - Center for Air Pollution Research (CAPR), Institute for Environmental Research 
      (IER), Tehran University of Medical Sciences, Tehran, Iran.
FAU - Djazayeri, Abolghasem
AU  - Djazayeri A
AD  - Department of Community Nutrition, School of Nutritional Sciences and Dietetics, 
      Tehran University of Medical Sciences, Tehran, Iran.
FAU - Malekafzali, Hossein
AU  - Malekafzali H
AD  - Vali-e-Asr Reproductive Health Research Center, Tehran University of Medical 
      Sciences, Tehran, Iran.
LA  - eng
PT  - Journal Article
PL  - Iran
TA  - J Family Reprod Health
JT  - Journal of family & reproductive health
JID - 101496684
PMC - PMC5241357
OTO - NOTNLM
OT  - Diet
OT  - Persistent Organic Pollutants
OT  - Polybrominated Diphenyl Ethers
OT  - Polychlorinated Biphenyls
OT  - Pregnancy
EDAT- 2017/01/20 06:00
MHDA- 2017/01/20 06:01
PMCR- 2016/09/01
CRDT- 2017/01/20 06:00
PHST- 2017/01/20 06:00 [entrez]
PHST- 2017/01/20 06:00 [pubmed]
PHST- 2017/01/20 06:01 [medline]
PHST- 2016/09/01 00:00 [pmc-release]
AID - JFRH-10-129 [pii]
PST - ppublish
SO  - J Family Reprod Health. 2016 Sep;10(3):129-138.