PMID- 28101770
OWN - NLM
STAT- MEDLINE
DCOM- 20180427
LR  - 20181113
IS  - 1867-0687 (Electronic)
VI  - 13
IP  - 3
DP  - 2017 Jun
TI  - Factors controlling fetal echocardiography determine the diagnostic accuracy of 
      isolated ventricular septal defect.
PG  - 278-281
LID - 10.1007/s12519-017-0009-6 [doi]
AB  - BACKGROUND: Fetal echocardiography (FECG) is a key screening tool for prenatal 
      cardiac abnormalities. Herein, we examined the ultrasonic factors determining 
      prenatal ultrasonic diagnosis of isolated ventricular septal defect (IVSD). 
      METHODS: The diagnostic role of ultrasonic factors was investigated in patients 
      in middle or late pregnancy, diagnosed with IVSD by FECG and confirmed using 
      postnatal echocardiography. RESULTS: One hundred and six patients with IVSD were 
      enrolled; the majority had perimembranous VSD. The combined imaging mode of 2 
      dimentional-echocardiography (2DE) and color doppler flow imaging (CDFI) showed 
      the highest rate (56.6%) of IVSD detection, while CDFIwas more efficient than 2DE 
      (32.1% vs. 11.3%). The single-view mode was more efficient than multiple-view 
      mode (75.5% vs. 24.5%). The highest efficient mode to detect IVSD was achieved 
      using combined imaging mode on the single view of the left ventricular outflow 
      tract view (LVOTV) (28.3%). FECG correctly classified 71.7% of fetal IVSD. There 
      was a significant difference of accuracy rate in classifying IVSD among the three 
      different imaging modes (chi (2)=7.141, P<0.05). The single imaging mode of CDFIand 
      the mode of CDFIcombined with 2DE correctly classified 75.9% and 75.0% of fetal 
      IVSD, respectively. LVOTV was the most accurate view of fetal IVSD classification 
      (85.2%; chi (2)=15.782, P<0.05). There was no difference in accuracies of IVSD 
      classification among multiple-view modes (chi (2)=2.343, P>0.05) or between 
      single-view mode and multiple-view mode (chi (2)=0.32, P>0.05). CONCLUSION: Single 
      LVOTV in CDFIor CDFIcombined with 2DE of FECG were the most effective diagnostic 
      modes for fetal IVSD diagnosis.
FAU - Chen, Jiao
AU  - Chen J
AD  - Department of Ultrasonography, West China Second University Hospital, Sichuan 
      University, Chengdu, China.
AD  - Key Laboratory of Birth Defects and Related Diseases of Women and Children 
      (Sichuan University), Ministry of Education, West China Second University 
      Hospital, Sichuan University, Chengdu, China.
FAU - Xie, Liang
AU  - Xie L
AD  - The Vascular Remodeling and Developmental Defects Research Unit, West China 
      Institute of Women and Children's Health, West China Second University Hospital, 
      Sichuan University, Chengdu, China.
AD  - Key Laboratory of Birth Defects and Related Diseases of Women and Children 
      (Sichuan University), Ministry of Education, West China Second University 
      Hospital, Sichuan University, Chengdu, China.
FAU - Liu, Han-Min
AU  - Liu HM
AD  - The Vascular Remodeling and Developmental Defects Research Unit, West China 
      Institute of Women and Children's Health, West China Second University Hospital, 
      Sichuan University, Chengdu, China. hanmin@vip.163.com.
AD  - Department of Pediatric Pneumology, West China Second University Hospital, 
      Sichuan University, Chengdu, China. hanmin@vip.163.com.
AD  - Key Laboratory of Birth Defects and Related Diseases of Women and Children 
      (Sichuan University), Ministry of Education, West China Second University 
      Hospital, Sichuan University, Chengdu, China. hanmin@vip.163.com.
LA  - eng
PT  - Journal Article
DEP - 20170119
PL  - Switzerland
TA  - World J Pediatr
JT  - World journal of pediatrics : WJP
JID - 101278599
SB  - IM
MH  - Adult
MH  - Diagnosis, Differential
MH  - Echocardiography/*methods
MH  - Female
MH  - Heart Defects, Congenital/*diagnostic imaging
MH  - Heart Septal Defects, Ventricular/*diagnostic imaging
MH  - Humans
MH  - Pregnancy
MH  - Pregnancy Outcome
MH  - Ultrasonography, Prenatal/*methods
OTO - NOTNLM
OT  - congenital heart diseases/defects
OT  - echocardiography
OT  - fetal-ultrasound
OT  - isolated ventricular septal defect
EDAT- 2017/01/20 06:00
MHDA- 2018/04/28 06:00
CRDT- 2017/01/20 06:00
PHST- 2016/04/01 00:00 [received]
PHST- 2016/06/28 00:00 [accepted]
PHST- 2017/01/20 06:00 [pubmed]
PHST- 2018/04/28 06:00 [medline]
PHST- 2017/01/20 06:00 [entrez]
AID - 10.1007/s12519-017-0009-6 [pii]
AID - 10.1007/s12519-017-0009-6 [doi]
PST - ppublish
SO  - World J Pediatr. 2017 Jun;13(3):278-281. doi: 10.1007/s12519-017-0009-6. Epub 
      2017 Jan 19.