PMID- 28102037 OWN - NLM STAT- MEDLINE DCOM- 20180607 LR - 20181202 IS - 2059-2310 (Electronic) IS - 2059-2302 (Print) IS - 2059-2302 (Linking) VI - 89 IP - 2 DP - 2017 Feb TI - In celebration of Ruggero Ceppellini: HLA in transplantation. PG - 71-76 LID - 10.1111/tan.12955 [doi] AB - The availability of hematopoietic cell transplantation as curative therapy for blood disorders has been dramatically improved through a better understanding of the human leukocyte antigen (HLA) barrier. Although a fully compatible unrelated donor is preferable, transplantation from donors with a limited degree of HLA mismatching is associated with acceptable outcomes in many cases. Research on the limits of HLA mismatching, and the features that define permissible HLA mismatches will continue to enable transplantation to be more broadly available to patients in need. CI - (c) 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd. FAU - Petersdorf, E W AU - Petersdorf EW AD - Fred Hutchinson Cancer Research Center, Division of Clinical Research, Seattle, Washington. LA - eng GR - P01 CA018029/CA/NCI NIH HHS/United States GR - R01 CA100019/CA/NCI NIH HHS/United States GR - U01 AI069197/AI/NIAID NIH HHS/United States GR - U01 CA162194/CA/NCI NIH HHS/United States PT - Biography PT - Historical Article PT - Journal Article PT - Portrait PT - Review PL - England TA - HLA JT - HLA JID - 101675570 RN - 0 (HLA Antigens) RN - 0 (Myeloablative Agonists) SB - IM MH - Alleles MH - Allergy and Immunology/history MH - Graft vs Host Disease/prevention & control MH - HLA Antigens/classification/*genetics/immunology MH - Hematologic Diseases/genetics/immunology/pathology/*therapy MH - Hematopoietic Stem Cell Transplantation/history/*methods MH - Histocompatibility Testing/*statistics & numerical data MH - History, 20th Century MH - Humans MH - Italy MH - Myeloablative Agonists/therapeutic use MH - *Registries MH - Transplantation Conditioning/methods MH - Transplantation, Homologous MH - Unrelated Donors/classification/*supply & distribution MH - Workforce PS - Ceppellini R FPS - Ceppellini, Ruggero PMC - PMC5267337 MID - NIHMS840006 OTO - NOTNLM OT - HLA OT - expression OT - haplotype OT - hematopoietic cell transplantation OT - matching OT - unrelated donor EDAT- 2017/01/20 06:00 MHDA- 2018/06/08 06:00 PMCR- 2018/02/01 CRDT- 2017/01/20 06:00 PHST- 2016/12/19 00:00 [received] PHST- 2016/12/19 00:00 [accepted] PHST- 2017/01/20 06:00 [entrez] PHST- 2017/01/20 06:00 [pubmed] PHST- 2018/06/08 06:00 [medline] PHST- 2018/02/01 00:00 [pmc-release] AID - 10.1111/tan.12955 [doi] PST - ppublish SO - HLA. 2017 Feb;89(2):71-76. doi: 10.1111/tan.12955.