PMID- 28109377 OWN - NLM STAT- MEDLINE DCOM- 20170414 LR - 20170817 IS - 1552-6259 (Electronic) IS - 0003-4975 (Linking) VI - 103 IP - 2 DP - 2017 Feb TI - Antineutrophil Cytoplasmic Antibody-Associated Multiple Giant Saccular Aortic Aneurysms. PG - e153-e155 LID - S0003-4975(16)30880-3 [pii] LID - 10.1016/j.athoracsur.2016.06.109 [doi] AB - We describe a very rare case of a 67-year-old man with multiple saccular aortic aneurysms throughout the entire aorta due to antineutrophil cytoplasmic antibody-associated vasculitis (AAV). The patient underwent staged aortic surgical procedures, including stent-graft insertion for a left iliac artery aneurysm, thoracic endovascular aortic repair for a descending aortic aneurysm, and total replacement of the ascending aorta and aortic arch with the use of high-dose steroids to control inflammation. The histologic findings demonstrated that the damage to the vasa vasorum of the adventitia resulting from AAV caused ischemia of the media, resulting in the formation of saccular aneurysmal changes. CI - Copyright (c) 2017 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved. FAU - Kinoshita, Ryoji AU - Kinoshita R AD - Department of Cardiovascular Surgery, Graduate School of Medical and Dental Science, Tokyo Medical and Dental University, Tokyo, Japan. FAU - Mizuno, Tomohiro AU - Mizuno T AD - Department of Cardiovascular Surgery, Graduate School of Medical and Dental Science, Tokyo Medical and Dental University, Tokyo, Japan. Electronic address: t-mizuno@yhc.att.ne.jp. FAU - Hachimaru, Tsuyoshi AU - Hachimaru T AD - Department of Cardiovascular Surgery, Graduate School of Medical and Dental Science, Tokyo Medical and Dental University, Tokyo, Japan. FAU - Oi, Keiji AU - Oi K AD - Department of Cardiovascular Surgery, Graduate School of Medical and Dental Science, Tokyo Medical and Dental University, Tokyo, Japan. FAU - Yashima, Masafumi AU - Yashima M AD - Department of Cardiovascular Surgery, Graduate School of Medical and Dental Science, Tokyo Medical and Dental University, Tokyo, Japan. FAU - Nagaoka, Eiki AU - Nagaoka E AD - Department of Cardiovascular Surgery, Graduate School of Medical and Dental Science, Tokyo Medical and Dental University, Tokyo, Japan. FAU - Fujiwara, Tatsuki AU - Fujiwara T AD - Department of Cardiovascular Surgery, Graduate School of Medical and Dental Science, Tokyo Medical and Dental University, Tokyo, Japan. FAU - Kuroki, Hidehito AU - Kuroki H AD - Department of Cardiovascular Surgery, Graduate School of Medical and Dental Science, Tokyo Medical and Dental University, Tokyo, Japan. FAU - Tasaki, Dai AU - Tasaki D AD - Department of Cardiovascular Surgery, Graduate School of Medical and Dental Science, Tokyo Medical and Dental University, Tokyo, Japan. FAU - Arai, Hirokuni AU - Arai H AD - Department of Cardiovascular Surgery, Graduate School of Medical and Dental Science, Tokyo Medical and Dental University, Tokyo, Japan. LA - eng PT - Case Reports PT - Journal Article PL - Netherlands TA - Ann Thorac Surg JT - The Annals of thoracic surgery JID - 15030100R SB - IM MH - Aged MH - Angioplasty/*methods MH - Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis/*complications/diagnosis MH - Aortic Aneurysm, Thoracic/diagnostic imaging/*immunology/*surgery MH - Blood Vessel Prosthesis Implantation/*methods MH - Computed Tomography Angiography/*methods MH - Follow-Up Studies MH - Humans MH - Imaging, Three-Dimensional MH - Male MH - Rare Diseases MH - Risk Assessment MH - Treatment Outcome MH - Vascular Surgical Procedures/methods EDAT- 2017/01/23 06:00 MHDA- 2017/04/15 06:00 CRDT- 2017/01/23 06:00 PHST- 2016/05/13 00:00 [received] PHST- 2016/06/17 00:00 [revised] PHST- 2016/06/28 00:00 [accepted] PHST- 2017/01/23 06:00 [entrez] PHST- 2017/01/23 06:00 [pubmed] PHST- 2017/04/15 06:00 [medline] AID - S0003-4975(16)30880-3 [pii] AID - 10.1016/j.athoracsur.2016.06.109 [doi] PST - ppublish SO - Ann Thorac Surg. 2017 Feb;103(2):e153-e155. doi: 10.1016/j.athoracsur.2016.06.109.