PMID- 28116164
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201001
IS  - 2090-2824 (Print)
IS  - 2090-2832 (Electronic)
IS  - 2090-2824 (Linking)
VI  - 2016
DP  - 2016
TI  - Predictors of Improved Walking after a Supervised Walking Exercise Program in Men 
      and Women with Peripheral Artery Disease.
PG  - 2191350
LID - 10.1155/2016/2191350 [doi]
LID - 2191350
AB  - We compared the changes in ambulatory outcomes between men and women with 
      symptomatic peripheral arterial disease (PAD) following completion of a 
      supervised, on-site, treadmill exercise program, and we determined whether 
      exercise training variables and baseline clinical characteristics were predictive 
      of changes in ambulatory outcomes in men and women. Twenty-three men and 25 women 
      completed the supervised exercise program, consisting of intermittent walking to 
      mild-to-moderate claudication pain for three months. Men and women significantly 
      increased claudication onset time (COT) (p < 0.001 and p < 0.01, resp.) and peak 
      walking time (PWT) (p < 0.001 for each group). However, change in PWT was less in 
      women (54%) than in men (77%) (p < 0.05). Neither group significantly changed 
      6-minute walk distance (6MWD). In women, baseline COT was the only predictor for 
      the change in COT (p = 0.007) and the change in PWT (p = 0.094). In men, baseline 
      COT (p < 0.01) and obesity (p < 0.10) were predictors for the change in COT, and 
      obesity was the only predictor for the change in PWT (p = 0.002). Following a 
      supervised, on-site, treadmill exercise program, women had less improvement in 
      PWT than men, and neither men nor women improved submaximal, overground 6MWD. 
      Furthermore, obese men and patients with lower baseline COT were least responsive 
      to supervised exercise. This trial is registered with ClinicalTrial.gov, unique 
      identifier: NCT00618670.
FAU - Gardner, Andrew W
AU  - Gardner AW
AUID- ORCID: 0000-0001-7721-5438
AD  - Reynolds Oklahoma Center on Aging, Donald W. Reynolds Department of Geriatric 
      Medicine, University of Oklahoma Health Sciences Center (OUHSC), Oklahoma City, 
      OK, USA; Veterans Affairs Medical Center, Oklahoma City, OK, USA.
FAU - Parker, Donald E
AU  - Parker DE
AUID- ORCID: 0000-0001-8780-6522
AD  - Department of Biostatistics and Epidemiology, OUHSC, Oklahoma City, OK, USA.
FAU - Montgomery, Polly S
AU  - Montgomery PS
AD  - Reynolds Oklahoma Center on Aging, Donald W. Reynolds Department of Geriatric 
      Medicine, University of Oklahoma Health Sciences Center (OUHSC), Oklahoma City, 
      OK, USA.
LA  - eng
SI  - ClinicalTrials.gov/NCT00618670
PT  - Journal Article
DEP - 20161225
PL  - United States
TA  - Int J Vasc Med
JT  - International journal of vascular medicine
JID - 101542608
PMC - PMC5220567
COIS- The authors declare that there is no conflict of interests regarding the 
      publication of this paper.
EDAT- 2017/01/25 06:00
MHDA- 2017/01/25 06:01
PMCR- 2016/12/25
CRDT- 2017/01/25 06:00
PHST- 2016/07/20 00:00 [received]
PHST- 2016/12/04 00:00 [accepted]
PHST- 2017/01/25 06:00 [entrez]
PHST- 2017/01/25 06:00 [pubmed]
PHST- 2017/01/25 06:01 [medline]
PHST- 2016/12/25 00:00 [pmc-release]
AID - 10.1155/2016/2191350 [doi]
PST - ppublish
SO  - Int J Vasc Med. 2016;2016:2191350. doi: 10.1155/2016/2191350. Epub 2016 Dec 25.