PMID- 28117280
OWN - NLM
STAT- MEDLINE
DCOM- 20180319
LR  - 20220129
IS  - 1969-6213 (Electronic)
IS  - 1774-024X (Linking)
VI  - 13
IP  - 2
DP  - 2017 Jun 2
TI  - Post-procedural myocardial infarction following surgical aortic valve replacement 
      and transcatheter aortic valve implantation.
PG  - e153-e160
LID - EIJ-D-16-00558 [pii]
LID - 10.4244/EIJ-D-16-00558 [doi]
AB  - AIMS: Myocardial injury assessed using cardiac biomarker release is ubiquitous 
      following surgical aortic valve replacement (SAVR) and transcatheter aortic valve 
      implantation (TAVI), preventing accurate discrimination between focal myocardial 
      infarction (MI) and global injury. Cardiovascular magnetic resonance (CMR) late 
      gadolinium enhancement (LGE) imaging was used to compare rates of new MI 
      following SAVR and TAVI. METHODS AND RESULTS: Identical CMR scans were obtained 
      at baseline and six months post procedure in ninety-six patients undergoing SAVR 
      (n=39) and TAVI (n=57). The rate of new MI was greater following SAVR than TAVI 
      (SAVR, n=10 [26%] vs. TAVI, n=3 [5%], p=0.004). Infarct mass was similar between 
      groups (SAVR 1.1+/-0.6 vs. TAVI 2.0+/-1.4 g, p=0.395). New MI did not impact on 
      change in LV ejection fraction (SAVR:LGE[+]2.2+/-4.7 vs. LGE[-]0.9+/-8.0%, p=0.437, 
      TAVI:LGE[+]-0.9+/-6.0 vs. LGE[-]2.0+/-7.8%, p=0.420). Thirty-four patients (60%) in 
      the TAVI group had non-revascularised coronary artery disease (CAD) at the time 
      of TAVI, of whom three (9%) had new MI. CONCLUSIONS: MI is an infrequent 
      complication of TAVI but is more common following SAVR. Infarct size is small 
      following both procedures. The low new infarct rate in TAVI, especially in the 
      context of high rates of non-revascularised CAD, strengthens data from previous 
      studies suggesting that coronary revascularisation pre-TAVI may be unnecessary.
FAU - Dobson, Laura E
AU  - Dobson LE
AD  - Multidisciplinary Cardiovascular Research Centre (MCRC) & Division of Biomedical 
      Imaging, LICAMM, University of Leeds, Leeds, United Kingdom.
FAU - Musa, Tarique A
AU  - Musa TA
FAU - Uddin, Akhlaque
AU  - Uddin A
FAU - Fairbairn, Timothy A
AU  - Fairbairn TA
FAU - Swoboda, Peter P
AU  - Swoboda PP
FAU - Ripley, David P
AU  - Ripley DP
FAU - Garg, Pankaj
AU  - Garg P
FAU - Evans, Betsy
AU  - Evans B
FAU - Malkin, Christopher J
AU  - Malkin CJ
FAU - Blackman, Daniel J
AU  - Blackman DJ
FAU - Plein, Sven
AU  - Plein S
FAU - Greenwood, John P
AU  - Greenwood JP
LA  - eng
GR  - PG/11/126/29321/BHF_/British Heart Foundation/United Kingdom
PT  - Comparative Study
PT  - Journal Article
PT  - Observational Study
DEP - 20170602
PL  - France
TA  - EuroIntervention
JT  - EuroIntervention : journal of EuroPCR in collaboration with the Working Group on 
      Interventional Cardiology of the European Society of Cardiology
JID - 101251040
RN  - 0 (Contrast Media)
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Aortic Valve/physiopathology/*surgery
MH  - Aortic Valve Stenosis/diagnosis/physiopathology/*surgery
MH  - Contrast Media/administration & dosage
MH  - Coronary Angiography
MH  - Female
MH  - Heart Valve Prosthesis Implantation/*adverse effects
MH  - Humans
MH  - Magnetic Resonance Imaging
MH  - Male
MH  - Myocardial Infarction/diagnostic imaging/*etiology/physiopathology
MH  - Predictive Value of Tests
MH  - Prospective Studies
MH  - Risk Factors
MH  - Severity of Illness Index
MH  - Time Factors
MH  - Transcatheter Aortic Valve Replacement/*adverse effects
MH  - Treatment Outcome
EDAT- 2017/01/25 06:00
MHDA- 2018/03/20 06:00
CRDT- 2017/01/25 06:00
PHST- 2017/01/25 06:00 [pubmed]
PHST- 2018/03/20 06:00 [medline]
PHST- 2017/01/25 06:00 [entrez]
AID - EIJ-D-16-00558 [pii]
AID - 10.4244/EIJ-D-16-00558 [doi]
PST - epublish
SO  - EuroIntervention. 2017 Jun 2;13(2):e153-e160. doi: 10.4244/EIJ-D-16-00558.