PMID- 28138816 OWN - NLM STAT- MEDLINE DCOM- 20171218 LR - 20181113 IS - 1875-8312 (Electronic) IS - 1569-5794 (Linking) VI - 33 IP - 6 DP - 2017 Jun TI - Cardiac MOLLI T(1) mapping at 3.0 T: comparison of patient-adaptive dual-source RF and conventional RF transmission. PG - 889-897 LID - 10.1007/s10554-017-1072-8 [doi] AB - To prospectively compare image quality and myocardial T(1) relaxation times of modified Look-Locker inversion recovery (MOLLI) imaging at 3.0 T (T) acquired with patient-adaptive dual-source (DS) and conventional single-source (SS) radiofrequency (RF) transmission. Pre- and post-contrast MOLLI T(1) mapping using SS and DS was acquired in 27 patients. Patient wise and segment wise analysis of T(1) times was performed. The correlation of DS MOLLI measurements with a reference spin echo sequence was analysed in phantom experiments. DS MOLLI imaging reduced T(1) standard deviation in 14 out of 16 myocardial segments (87.5%). Significant reduction of T(1) variance could be obtained in 7 segments (43.8%). DS significantly reduced myocardial T(1) variance in 16 out of 25 patients (64.0%). With conventional RF transmission, dielectric shading artefacts occurred in six patients causing diagnostic uncertainty. No according artefacts were found on DS images. DS image findings were in accordance with conventional T(1) mapping and late gadolinium enhancement (LGE) imaging. Phantom experiments demonstrated good correlation of myocardial T(1) time between DS MOLLI and spin echo imaging. Dual-source RF transmission enhances myocardial T(1) homogeneity in MOLLI imaging at 3.0 T. The reduction of signal inhomogeneities and artefacts due to dielectric shading is likely to enhance diagnostic confidence. FAU - Rasper, Michael AU - Rasper M AD - Department of Diagnostic and Interventional Radiology, Klinikum rechts der Isar der Technischen Universitat Munchen, Ismaninger Str. 22, 81675, Munich, Germany. michael.rasper@tum.de. FAU - Nadjiri, Jonathan AU - Nadjiri J AD - Department of Diagnostic and Interventional Radiology, Klinikum rechts der Isar der Technischen Universitat Munchen, Ismaninger Str. 22, 81675, Munich, Germany. FAU - Strater, Alexandra S AU - Strater AS AD - Department of Diagnostic and Interventional Radiology, Klinikum rechts der Isar der Technischen Universitat Munchen, Ismaninger Str. 22, 81675, Munich, Germany. FAU - Settles, Marcus AU - Settles M AD - Department of Diagnostic and Interventional Radiology, Klinikum rechts der Isar der Technischen Universitat Munchen, Ismaninger Str. 22, 81675, Munich, Germany. FAU - Laugwitz, Karl-Ludwig AU - Laugwitz KL AD - Department of Cardiology, Klinikum rechts der Isar der Technischen Universitat Munchen, Ismaninger Str. 22, 81675, Munich, Germany. FAU - Rummeny, Ernst J AU - Rummeny EJ AD - Department of Diagnostic and Interventional Radiology, Klinikum rechts der Isar der Technischen Universitat Munchen, Ismaninger Str. 22, 81675, Munich, Germany. FAU - Huber, Armin M AU - Huber AM AD - Department of Diagnostic and Interventional Radiology, Klinikum rechts der Isar der Technischen Universitat Munchen, Ismaninger Str. 22, 81675, Munich, Germany. LA - eng PT - Comparative Study PT - Journal Article DEP - 20170130 PL - United States TA - Int J Cardiovasc Imaging JT - The international journal of cardiovascular imaging JID - 100969716 RN - 0 (Contrast Media) RN - K2I13DR72L (Gadolinium DTPA) SB - IM MH - Adult MH - Aged MH - Aged, 80 and over MH - Artifacts MH - Contrast Media/administration & dosage MH - Female MH - Gadolinium DTPA/administration & dosage MH - Heart Diseases/*diagnostic imaging/pathology MH - Humans MH - Image Interpretation, Computer-Assisted/*methods MH - Magnetic Resonance Imaging, Cine/instrumentation/*methods MH - Male MH - Middle Aged MH - Myocardium/*pathology MH - Phantoms, Imaging MH - Predictive Value of Tests MH - Reproducibility of Results MH - Young Adult OTO - NOTNLM OT - 3 T OT - Cardiac T1 mapping OT - Dual-source RF transmission OT - MOLLI OT - RF shimming EDAT- 2017/02/01 06:00 MHDA- 2017/12/19 06:00 CRDT- 2017/02/01 06:00 PHST- 2016/09/21 00:00 [received] PHST- 2017/01/12 00:00 [accepted] PHST- 2017/02/01 06:00 [pubmed] PHST- 2017/12/19 06:00 [medline] PHST- 2017/02/01 06:00 [entrez] AID - 10.1007/s10554-017-1072-8 [pii] AID - 10.1007/s10554-017-1072-8 [doi] PST - ppublish SO - Int J Cardiovasc Imaging. 2017 Jun;33(6):889-897. doi: 10.1007/s10554-017-1072-8. Epub 2017 Jan 30.