PMID- 28142013 OWN - NLM STAT- MEDLINE DCOM- 20170217 LR - 20181113 IS - 1349-9092 (Electronic) IS - 0917-5040 (Print) IS - 0917-5040 (Linking) VI - 27 IP - 2 DP - 2017 Feb TI - Association between serum concentrations of persistent organic pollutants and smoking in Koreans: A cross-sectional study. PG - 63-68 LID - S0917-5040(16)30078-8 [pii] LID - 10.1016/j.je.2016.09.006 [doi] AB - BACKGROUND: Studies on the associations between persistent organic pollutants (POPs) and smoking according to gender and smoking amount (cigarettes/day) are limited, and the results regarding the relationship between POPs and smoking are not completely consistent across studies. OBJECTIVES: The smoking rate in Korea is one of the highest among the Organization for Economic Cooperation and Development (OECD) countries. We investigated the association between serum concentrations of POPs and cigarette smoking in Koreans by smoking status (never-smoker/ever-smoker) and smoking amount (cigarettes/day) according to gender. METHODS: Serum concentrations of 32 polychlorinated biphenyls (PCBs) and 19 organochlorine pesticides (OCPs) were measured in 401 participants (232 men and 169 women) who received health examinations during the Korean Cancer Prevention Study-II. We compared POP levels in ever-smokers and never-smokers and conducted multivariate logistic regression analyses to identify associations between POPs and smoking. RESULTS: Among women, the concentrations of PCB 156, PCB 167, and PCB 180 were significantly higher in ever-smokers than in never-smokers. After adjustments for age, body mass index, gamma-glutamyl transpeptidase, and alcohol intake, serum PCB 157 concentration was positively associated with male ever-smokers (OR 2.26; 95% CI, 1.01-5.04). In addition, trans-nonachlordane in OCPs as well as PCBs was significantly positively related with female ever-smokers (OR 3.21; 95% CI, 1.04-9.86). We found that subjects who smoked fewer than 15 cigarettes/day had a higher risk of having high POP concentrations than never-smokers. CONCLUSIONS: These results indicate that smoking may be associated with human serum POPs levels. CI - Copyright (c) 2016. Production and hosting by Elsevier B.V. FAU - Moon, Ho Jung AU - Moon HJ AD - Institute for Health Promotion & Department of Epidemiology and Health Promotion, Graduate School of Public Health, Yonsei University, Seoul, Republic of Korea. FAU - Lim, Jung-Eun AU - Lim JE AD - Department of Public Health, Graduate School, Yonsei University, Seoul, Republic of Korea. FAU - Jee, Sun Ha AU - Jee SH AD - Institute for Health Promotion & Department of Epidemiology and Health Promotion, Graduate School of Public Health, Yonsei University, Seoul, Republic of Korea. Electronic address: jsunha@yuhs.ac. LA - eng PT - Journal Article DEP - 20161115 PL - Japan TA - J Epidemiol JT - Journal of epidemiology JID - 9607688 RN - 0 (Environmental Pollutants) RN - 0 (Hydrocarbons, Chlorinated) RN - 0 (Pesticides) RN - 38380-08-4 (2,3,3',4,4',5-hexachlorobiphenyl) RN - 52I0CG8IQX (PCB 180) RN - DFC2HB4I0K (Polychlorinated Biphenyls) SB - IM MH - Adult MH - Aged MH - Cross-Sectional Studies MH - Environmental Pollutants/*blood MH - Female MH - Humans MH - Hydrocarbons, Chlorinated/*blood MH - Male MH - Middle Aged MH - Pesticides/*blood MH - Polychlorinated Biphenyls/*blood MH - Republic of Korea/epidemiology MH - Risk MH - Sex Distribution MH - Smoking/blood/*epidemiology MH - Young Adult PMC - PMC5328728 OTO - NOTNLM OT - Organochlorine pesticide OT - Persistent organic pollutant OT - Polychlorinated biphenyl OT - Smoking EDAT- 2017/02/01 06:00 MHDA- 2017/02/18 06:00 PMCR- 2016/11/15 CRDT- 2017/02/01 06:00 PHST- 2015/11/21 00:00 [received] PHST- 2016/03/17 00:00 [accepted] PHST- 2017/02/01 06:00 [entrez] PHST- 2017/02/01 06:00 [pubmed] PHST- 2017/02/18 06:00 [medline] PHST- 2016/11/15 00:00 [pmc-release] AID - S0917-5040(16)30078-8 [pii] AID - JE12 [pii] AID - 10.1016/j.je.2016.09.006 [doi] PST - ppublish SO - J Epidemiol. 2017 Feb;27(2):63-68. doi: 10.1016/j.je.2016.09.006. Epub 2016 Nov 15.