PMID- 28143499
OWN - NLM
STAT- MEDLINE
DCOM- 20171018
LR  - 20221207
IS  - 1475-2891 (Electronic)
IS  - 1475-2891 (Linking)
VI  - 16
IP  - 1
DP  - 2017 Jan 31
TI  - Relationship between coffee consumption and stroke risk in Korean population: the 
      Health Examinees (HEXA) Study.
PG  - 7
LID - 10.1186/s12937-017-0232-y [doi]
LID - 7
AB  - BACKGROUND: Although coffee consumption is increasing rapidly, the results of 
      previous studies regarding the association between coffee consumption and stroke 
      risk have been conflicting. This was a multi-center cross-sectional study that 
      aimed to evaluate the relationship between coffee consumption and stroke risk in 
      Korean population. METHODS: Data were obtained from the Health Examinees (HEXA) 
      Study, which involved 146,830 individuals aged 40-69 years. Coffee consumption 
      was categorized as none, < 1 cup/day, 1 to < 3 cups/day, and >/= 3 cups/day. We 
      used logistic regression models to examine the association between coffee 
      consumption and the risk of stroke while controlling for potential confounders 
      and performed subgroup analyses. RESULTS: After adjusting for age and various 
      possible confounders, high coffee consumption was associated with a 38% lower 
      odds ratio for stroke in women (none vs. >/= 3 cups/day: OR, 0.62; 95% CI 
      0.47-0.81; P for trend < 0.0001). No significant association was found in men 
      (none vs. >/= 3 cups/day: OR, 0.84; 95% CI, 0.66-1.07; P for trend = 0.1515). In 
      analyses stratified by covariates, an inverse association between coffee 
      consumption and stroke risk was most evident among healthy women who were 
      younger, non-obese, non-hypertensive, non-diabetic, non-smokers, and non-alcohol 
      drinkers. CONCLUSION: Our results suggest that higher coffee consumption may have 
      protective benefits with regards to stroke risk in middle-aged Korean women.
FAU - Lee, Jeeyoo
AU  - Lee J
AD  - Department of Nutritional Science and Food Management, Ewha Womans University, 52 
      Ewhayeodae-gil, 03760, Seodaemun-gu, Seoul, South Korea.
FAU - Lee, Ji-Eun
AU  - Lee JE
AD  - Department of Physical Education, College of Education, Chung-Ang University, 
      06974, Seoul, Republic of Korea.
FAU - Kim, Yuri
AU  - Kim Y
AD  - Department of Nutritional Science and Food Management, Ewha Womans University, 52 
      Ewhayeodae-gil, 03760, Seodaemun-gu, Seoul, South Korea. yuri.kim@ewha.ac.kr.
LA  - eng
PT  - Journal Article
DEP - 20170131
PL  - England
TA  - Nutr J
JT  - Nutrition journal
JID - 101152213
RN  - 0 (Coffee)
SB  - IM
MH  - Aged
MH  - Asian People
MH  - *Coffee
MH  - Cross-Sectional Studies
MH  - Female
MH  - Humans
MH  - Life Style
MH  - Logistic Models
MH  - Male
MH  - Middle Aged
MH  - Prevalence
MH  - Republic of Korea
MH  - Risk Factors
MH  - Socioeconomic Factors
MH  - Stroke/*epidemiology
MH  - Surveys and Questionnaires
PMC - PMC5282694
OTO - NOTNLM
OT  - HEXA
OT  - Korean
OT  - coffee
OT  - stroke
EDAT- 2017/02/02 06:00
MHDA- 2017/10/19 06:00
PMCR- 2017/01/31
CRDT- 2017/02/02 06:00
PHST- 2016/10/27 00:00 [received]
PHST- 2017/01/23 00:00 [accepted]
PHST- 2017/02/02 06:00 [entrez]
PHST- 2017/02/02 06:00 [pubmed]
PHST- 2017/10/19 06:00 [medline]
PHST- 2017/01/31 00:00 [pmc-release]
AID - 10.1186/s12937-017-0232-y [pii]
AID - 232 [pii]
AID - 10.1186/s12937-017-0232-y [doi]
PST - epublish
SO  - Nutr J. 2017 Jan 31;16(1):7. doi: 10.1186/s12937-017-0232-y.