PMID- 28150403 OWN - NLM STAT- MEDLINE DCOM- 20170605 LR - 20170605 IS - 1447-0756 (Electronic) IS - 1341-8076 (Linking) VI - 43 IP - 2 DP - 2017 Feb TI - Anti-N-methyl-d-aspartate receptor limbic encephalitis associated with mature cystic teratoma of the fallopian tube. PG - 412-415 LID - 10.1111/jog.13221 [doi] AB - Anti-N-methyl-d-aspartate receptor (NMDAR) limbic encephalitis is the most common form of paraneoplastic encephalitis that is associated with teratomas. Because tumor removal leads to better clinical outcomes, it is essential to reveal the location of the teratomas. This is the first reported case of anti-NMDAR encephalitis associated with teratoma of the fallopian tube. Salpingo-oophorectomy improved neurological symptoms and immunohistochemical examinations indicated the expression of NMDAR on neuroglial cells within the fallopian tube teratoma. Teratomas of the fallopian tube cause anti-NMDAR encephalitis; the imaging analysis and exploratory laparoscopies of the fallopian tube as well as of the ovary should be considered. Surgical removal of both fallopian tubes and ovaries with a normal appearance should be considered for patients in whom immunotherapy is not effective. CI - (c) 2017 Japan Society of Obstetrics and Gynecology. FAU - Hattori, Yukio AU - Hattori Y AD - Department of Obstetrics and Gynecology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan. FAU - Yamashita, Yoriko AU - Yamashita Y AD - Department of Experimental Pathology and Tumor Biology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan. FAU - Mizuno, Masayuki AU - Mizuno M AD - Department of Neurology and Neuroscience, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan. FAU - Katano, Kinue AU - Katano K AD - Department of Obstetrics and Gynecology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan. FAU - Sugiura-Ogasawara, Mayumi AU - Sugiura-Ogasawara M AD - Department of Obstetrics and Gynecology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan. FAU - Matsukawa, Noriyuki AU - Matsukawa N AD - Department of Neurology and Neuroscience, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan. LA - eng PT - Case Reports PL - Australia TA - J Obstet Gynaecol Res JT - The journal of obstetrics and gynaecology research JID - 9612761 SB - IM MH - Adult MH - Anti-N-Methyl-D-Aspartate Receptor Encephalitis/*etiology MH - Fallopian Tube Neoplasms/*complications/surgery MH - Female MH - Humans MH - Limbic Encephalitis/*etiology MH - Ovariectomy MH - Salpingectomy MH - Teratoma/*complications/surgery OTO - NOTNLM OT - anti-N-methyl-d-aspartate receptor OT - exploratory laparoscopy OT - fallopian tube teratomalimbic encephalitissalpingo-oophorectomy EDAT- 2017/02/06 06:00 MHDA- 2017/06/06 06:00 CRDT- 2017/02/03 06:00 PHST- 2016/04/10 00:00 [received] PHST- 2016/08/10 00:00 [revised] PHST- 2016/09/22 00:00 [accepted] PHST- 2017/02/03 06:00 [entrez] PHST- 2017/02/06 06:00 [pubmed] PHST- 2017/06/06 06:00 [medline] AID - 10.1111/jog.13221 [doi] PST - ppublish SO - J Obstet Gynaecol Res. 2017 Feb;43(2):412-415. doi: 10.1111/jog.13221.