PMID- 28163727 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20201001 IS - 1735-1995 (Print) IS - 1735-7136 (Electronic) IS - 1735-1995 (Linking) VI - 21 DP - 2016 TI - A preliminary study on the potential of Mycoplasma pneumoniae to induce dyskaryotic change in respiratory epithelium in adult community-acquired pneumonia. PG - 81 LID - 10.4103/1735-1995.192497 [doi] LID - 81 AB - BACKGROUND: This study aimed to explore the cellular morphology of respiratory epithelium in Mycoplasma pneumonia (MpP) patients. MATERIALS AND METHODS: The cast-off cell morphological findings from bronchoscopic brushings in MpP and community-acquired pneumonia (CAP) caused by typical pathogens were reviewed. RESULTS: Compared with the CAP group, cellular dysplasia in respiratory tract epithelial brushings was significantly greater in MpP patients (P = 0.033). CONCLUSION: Unique biological characteristics and mechanisms of pathogenesis of Mycoplasma pneumoniae (Mp) may result in dyskaryotic changes in respiratory epithelium in adult MpP. FAU - An, Shu-Chang AU - An SC AD - Department of Respiratory Medicine, First Hospital of Tsinghua University, Beijing, China. FAU - Yang, Dong-Hong AU - Yang DH AD - Department of Respiratory and Critical Care Medicine, Peking University People's Hospital, Beijing, China. FAU - Luo, Chao-Feng AU - Luo CF AD - Department of Radiology, First Hospital of Tsinghua University, Beijing, China. FAU - Chen, Xin AU - Chen X AD - Department of Pathology, First Hospital of Tsinghua University, Beijing, China. FAU - Liu, Guo-Tian AU - Liu GT AD - Department of Respiratory Medicine, First Hospital of Tsinghua University, Beijing, China. FAU - Weng, Yan AU - Weng Y AD - Department of Pathology, First Hospital of Tsinghua University, Beijing, China. FAU - Liu, Jing-Zhe AU - Liu JZ AD - Department of Radiology, First Hospital of Tsinghua University, Beijing, China. FAU - Shang, Ying AU - Shang Y AD - Department of Respiratory and Critical Care Medicine, Peking University People's Hospital, Beijing, China. FAU - Wang, Rui-Qin AU - Wang RQ AD - Department of Respiratory Medicine, First Hospital of Tsinghua University, Beijing, China. FAU - Gao, Zhan-Cheng AU - Gao ZC AD - Department of Respiratory and Critical Care Medicine, Peking University People's Hospital, Beijing, China. LA - eng PT - Journal Article DEP - 20161018 PL - India TA - J Res Med Sci JT - Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences JID - 101235599 PMC - PMC5244644 OTO - NOTNLM OT - Cellular dysplasia OT - Mycoplasma pneumonia OT - community-acquired pneumonia COIS- There are no conflicts of interest. EDAT- 2017/02/07 06:00 MHDA- 2017/02/07 06:01 PMCR- 2016/10/18 CRDT- 2017/02/07 06:00 PHST- 2016/02/26 00:00 [received] PHST- 2016/06/06 00:00 [revised] PHST- 2016/06/20 00:00 [accepted] PHST- 2017/02/07 06:00 [entrez] PHST- 2017/02/07 06:00 [pubmed] PHST- 2017/02/07 06:01 [medline] PHST- 2016/10/18 00:00 [pmc-release] AID - JRMS-21-81 [pii] AID - 10.4103/1735-1995.192497 [doi] PST - epublish SO - J Res Med Sci. 2016 Oct 18;21:81. doi: 10.4103/1735-1995.192497. eCollection 2016.