PMID- 2816699 OWN - NLM STAT- MEDLINE DCOM- 19891205 LR - 20190626 IS - 0002-8703 (Print) IS - 0002-8703 (Linking) VI - 118 IP - 5 Pt 1 DP - 1989 Nov TI - Percutaneous balloon mitral valvuloplasty in children and young adults with rheumatic mitral stenosis. PG - 883-7 AB - Twenty-eight patients with mitral stenosis, 17 females and 11 males, underwent percutaneous balloon mitral valvuloplasty (BMV). The age range was 10 to 30 (mean 17.8 +/- 6.7) years and all were symptomatic (New York Heart Association [NYHA] class III, 12 patients; class IV, 16 patients). BMV was done with a single balloon in 10 patients and double balloon in 16 patients. Following BMV, there was a significant reduction in transmitral end-diastolic pressure gradient from 23.1 +/- 5.8 to 7.6 +/- 4.2 mm Hg (p less than 0.001) and a significant increase in mitral valve area from 1.06 +/- 0.29 to 2.64 +/- 1.35 cm2 (p less than 0.001), along with an increase in cardiac index from 3.40 +/- 1.18 to 4.26 +/- 1.46 L/min/m2 (p less than 0.01). Improvement in symptomatic status by at least one NYHA class was seen in all patients. Mild mitral regurgitation developed in four and moderate mitral regurgitation developed in one patient. Angiographic evidence of atrial septal defect was present in one patient. Follow-up at 8 to 12 weeks in 12 patients has shown sustained hemodynamic improvement. These short-term results indicate that BMV is an effective nonsurgical procedure for the management of patients with rheumatic mitral stenosis. FAU - Arora, R AU - Arora R AD - Department of Cardiology, G.B. Pant Hospital, New Dehli, India. FAU - Nair, M AU - Nair M FAU - Rajagopal, S AU - Rajagopal S FAU - Sethi, K K AU - Sethi KK FAU - Mohan, J C AU - Mohan JC FAU - Nigam, M AU - Nigam M FAU - Khalilullah, M AU - Khalilullah M LA - eng PT - Journal Article PL - United States TA - Am Heart J JT - American heart journal JID - 0370465 SB - IM MH - Adolescent MH - Adult MH - Cardiovascular Diseases/etiology MH - *Catheterization MH - Cerebrovascular Disorders/etiology MH - Child MH - Evaluation Studies as Topic MH - Female MH - Hemodynamics MH - Humans MH - Male MH - Mitral Valve Stenosis/etiology/physiopathology/*therapy MH - Postoperative Complications MH - Postoperative Period MH - Rheumatic Diseases/*complications MH - Severity of Illness Index EDAT- 1989/11/01 00:00 MHDA- 1989/11/01 00:01 CRDT- 1989/11/01 00:00 PHST- 1989/11/01 00:00 [pubmed] PHST- 1989/11/01 00:01 [medline] PHST- 1989/11/01 00:00 [entrez] AID - 0002-8703(89)90218-4 [pii] AID - 10.1016/0002-8703(89)90218-4 [doi] PST - ppublish SO - Am Heart J. 1989 Nov;118(5 Pt 1):883-7. doi: 10.1016/0002-8703(89)90218-4.