PMID- 28167808
OWN - NLM
STAT- MEDLINE
DCOM- 20170616
LR  - 20171220
IS  - 1477-9145 (Electronic)
IS  - 0022-0949 (Linking)
VI  - 220
IP  - Pt 8
DP  - 2017 Apr 15
TI  - How do individuals cope with stress? Behavioural, physiological and neuronal 
      differences between proactive and reactive coping styles in fish.
PG  - 1524-1532
LID - 10.1242/jeb.153213 [doi]
AB  - Despite the use of fish models to study human mental disorders and dysfunctions, 
      knowledge of regional telencephalic responses in non-mammalian vertebrates 
      expressing alternative stress coping styles is poor. As perception of salient 
      stimuli associated with stress coping in mammals is mainly under forebrain limbic 
      control, we tested region-specific forebrain neural (i.e. mRNA abundance and 
      monoamine neurochemistry) and endocrine responses under basal and acute stress 
      conditions for previously characterised proactive and reactive Atlantic salmon. 
      Reactive fish showed a higher degree of the neurogenesis marker proliferating 
      cell nuclear antigen (pcna) and dopamine activity under basal conditions in the 
      proposed hippocampus homologue (Dl) and higher post-stress plasma cortisol 
      levels. Proactive fish displayed higher post-stress serotonergic signalling (i.e. 
      higher serotonergic activity and expression of the 5-HT(1A) receptor) in the 
      proposed amygdala homologue (Dm), increased expression of the neuroplasticity 
      marker brain-derived neurotropic factor (bdnf) in both Dl and the lateral septum 
      homologue (Vv), as well as increased expression of the corticotropin releasing 
      factor 1 (crf(1) ) receptor in the Dl, in line with active coping neuro-profiles 
      reported in the mammalian literature. We present novel evidence of proposed 
      functional equivalences in the fish forebrain with mammalian limbic structures.
CI  - (c) 2017. Published by The Company of Biologists Ltd.
FAU - Vindas, Marco A
AU  - Vindas MA
AUID- ORCID: 0000-0002-3996-0952
AD  - Uni Environment, Uni Research AS, Bergen NO-5020, Norway marco.vindas@uni.no.
AD  - Department of Biosciences, University of Oslo, Oslo NO-0316, Norway.
FAU - Gorissen, Marnix
AU  - Gorissen M
AD  - Radboud University, Institute for Water and Wetland Research, Department of 
      Animal Ecology & Physiology, Nijmegen 6525 AJ, The Netherlands.
FAU - Hoglund, Erik
AU  - Hoglund E
AD  - National Institute of Aquatic Resources, Technical University of Denmark, 
      Hirtshals DK-9850, Denmark.
FAU - Flik, Gert
AU  - Flik G
AD  - Radboud University, Institute for Water and Wetland Research, Department of 
      Animal Ecology & Physiology, Nijmegen 6525 AJ, The Netherlands.
FAU - Tronci, Valentina
AU  - Tronci V
AD  - Uni Environment, Uni Research AS, Bergen NO-5020, Norway.
FAU - Damsgard, Borge
AU  - Damsgard B
AD  - The University Centre of Svalbard, Longyearbyen NO-9171, Norway.
AD  - Nofima, Tromso NO-9291, Norway.
FAU - Thornqvist, Per-Ove
AU  - Thornqvist PO
AD  - Department of Neuroscience, Uppsala University, Uppsala SE-75124, Sweden.
FAU - Nilsen, Tom O
AU  - Nilsen TO
AD  - Uni Environment, Uni Research AS, Bergen NO-5020, Norway.
FAU - Winberg, Svante
AU  - Winberg S
AD  - Department of Neuroscience, Uppsala University, Uppsala SE-75124, Sweden.
FAU - Overli, Oyvind
AU  - Overli O
AD  - Department of Food Safety and Infection Biology, Norwegian University of Life 
      Sciences, Oslo NO-0033, Norway.
FAU - Ebbesson, Lars O E
AU  - Ebbesson LOE
AD  - Uni Environment, Uni Research AS, Bergen NO-5020, Norway.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20170206
PL  - England
TA  - J Exp Biol
JT  - The Journal of experimental biology
JID - 0243705
RN  - 0 (Brain-Derived Neurotrophic Factor)
RN  - 0 (Proliferating Cell Nuclear Antigen)
RN  - 0 (RNA, Messenger)
RN  - 112692-38-3 (Receptor, Serotonin, 5-HT1A)
RN  - S88TT14065 (Oxygen)
RN  - WI4X0X7BPJ (Hydrocortisone)
SB  - IM
MH  - Animal Migration
MH  - Animals
MH  - Brain-Derived Neurotrophic Factor/genetics/metabolism
MH  - Hydrocortisone/blood
MH  - Neurogenesis
MH  - Neuronal Plasticity
MH  - Oxygen/metabolism
MH  - Proliferating Cell Nuclear Antigen/genetics/metabolism
MH  - Prosencephalon/*physiology
MH  - RNA, Messenger/genetics
MH  - Receptor, Serotonin, 5-HT1A/genetics/metabolism
MH  - Salmo salar/blood/*physiology
MH  - *Stress, Physiological
MH  - Transcription, Genetic
OTO - NOTNLM
OT  - Atlantic salmon
OT  - BDNF
OT  - Limbic areas
OT  - Neural plasticity
OT  - Serotonin
COIS- Competing interestsThe authors declare no competing or financial interests.
EDAT- 2017/02/09 06:00
MHDA- 2017/06/18 06:00
CRDT- 2017/02/08 06:00
PHST- 2016/11/14 00:00 [received]
PHST- 2017/02/01 00:00 [accepted]
PHST- 2017/02/09 06:00 [pubmed]
PHST- 2017/06/18 06:00 [medline]
PHST- 2017/02/08 06:00 [entrez]
AID - jeb.153213 [pii]
AID - 10.1242/jeb.153213 [doi]
PST - ppublish
SO  - J Exp Biol. 2017 Apr 15;220(Pt 8):1524-1532. doi: 10.1242/jeb.153213. Epub 2017 
      Feb 6.