PMID- 28169151
OWN - NLM
STAT- MEDLINE
DCOM- 20180306
LR  - 20220318
IS  - 1878-1861 (Electronic)
IS  - 1878-1861 (Linking)
VI  - 20
IP  - 7
DP  - 2017 Jul
TI  - Value of quantitative MRI parameters in predicting and evaluating clinical 
      outcome in conservatively treated patients with chronic midportion Achilles 
      tendinopathy: A prospective study.
PG  - 633-637
LID - S1440-2440(17)30264-5 [pii]
LID - 10.1016/j.jsams.2017.01.234 [doi]
AB  - OBJECTIVES: To evaluate whether baseline MRI parameters provide prognostic value 
      for clinical outcome, and to study correlation between MRI parameters and 
      clinical outcome. DESIGN: Observational prospective cohort study. METHODS: 
      Patients with chronic midportion Achilles tendinopathy were included and 
      performed a 16-week eccentric calf-muscle exercise program. Outcome measurements 
      were the validated Victorian Institute of Sports Assessment-Achilles (VISA-A) 
      questionnaire and MRI parameters at baseline and after 24 weeks. The following 
      MRI parameters were assessed: tendon volume (Volume), tendon maximum 
      cross-sectional area (CSA), tendon maximum anterior-posterior diameter (AP), and 
      signal intensity (SI). Intra-class correlation coefficients (ICCs) and minimum 
      detectable changes (MDCs) for each parameter were established in a reliability 
      analysis. RESULTS: Twenty-five patients were included and complete follow-up was 
      achieved in 20 patients. The average VISA-A scores increased significantly with 
      12.3 points (27.6%). The reliability was fair-good for all MRI-parameters with 
      ICCs>0.50. Average tendon volume and CSA decreased significantly with 0.28cm(3) 
      (5.2%) and 4.52mm(2) (4.6%) respectively. Other MRI parameters did not change 
      significantly. None of the baseline MRI parameters were univariately associated 
      with VISA-A change after 24 weeks. MRI SI increase over 24 weeks was positively 
      correlated with the VISA-A score improvement (B=0.7, R(2)=0.490, p=0.02). 
      CONCLUSIONS: Tendon volume and CSA decreased significantly after 24 weeks of 
      conservative treatment. As these differences were within the MDC limits, they 
      could be a result of a measurement error. Furthermore, MRI parameters at baseline 
      did not predict the change in symptoms, and therefore have no added value in 
      providing a prognosis in daily clinical practice.
CI  - Copyright (c) 2017 Sports Medicine Australia. Published by Elsevier Ltd. All rights 
      reserved.
FAU - Tsehaie, J
AU  - Tsehaie J
AD  - Department of Orthopaedics, Erasmus Medical Centre, The Netherlands. Electronic 
      address: jonathantsehaie@gmail.com.
FAU - Poot, D H J
AU  - Poot DHJ
AD  - Department of Medical Informatics & Radiology, Erasmus Medical Centre, The 
      Netherlands.
FAU - Oei, E H G
AU  - Oei EHG
AD  - Department of Radiology, Erasmus Medical Centre, The Netherlands.
FAU - Verhaar, J A N
AU  - Verhaar JAN
AD  - Department of Orthopaedics, Erasmus Medical Centre, The Netherlands.
FAU - de Vos, R J
AU  - de Vos RJ
AD  - Department of Orthopaedics, Erasmus Medical Centre, The Netherlands.
LA  - eng
PT  - Journal Article
PT  - Observational Study
DEP - 20170124
PL  - Australia
TA  - J Sci Med Sport
JT  - Journal of science and medicine in sport
JID - 9812598
SB  - IM
MH  - Achilles Tendon/*diagnostic imaging/physiopathology
MH  - Adult
MH  - *Conservative Treatment
MH  - Exercise Therapy
MH  - Female
MH  - Humans
MH  - Image Processing, Computer-Assisted
MH  - *Magnetic Resonance Imaging
MH  - Male
MH  - Middle Aged
MH  - Observer Variation
MH  - Prognosis
MH  - Prospective Studies
MH  - Reproducibility of Results
MH  - Tendinopathy/*diagnostic imaging/*therapy
OTO - NOTNLM
OT  - Achilles tendon
OT  - Eccentric calf muscle exercise
OT  - MRI
OT  - Prognosis
OT  - Tendinopathy
OT  - VISA-A
EDAT- 2017/02/09 06:00
MHDA- 2018/03/07 06:00
CRDT- 2017/02/08 06:00
PHST- 2016/05/29 00:00 [received]
PHST- 2016/08/19 00:00 [revised]
PHST- 2017/01/17 00:00 [accepted]
PHST- 2017/02/09 06:00 [pubmed]
PHST- 2018/03/07 06:00 [medline]
PHST- 2017/02/08 06:00 [entrez]
AID - S1440-2440(17)30264-5 [pii]
AID - 10.1016/j.jsams.2017.01.234 [doi]
PST - ppublish
SO  - J Sci Med Sport. 2017 Jul;20(7):633-637. doi: 10.1016/j.jsams.2017.01.234. Epub 
      2017 Jan 24.