PMID- 28177178
OWN - NLM
STAT- MEDLINE
DCOM- 20180219
LR  - 20180219
IS  - 1440-1819 (Electronic)
IS  - 1323-1316 (Linking)
VI  - 71
IP  - 6
DP  - 2017 Jun
TI  - Association of premorbid personality with behavioral and psychological symptoms 
      in dementia with Lewy bodies: Comparison with Alzheimer's disease patients.
PG  - 409-416
LID - 10.1111/pcn.12511 [doi]
AB  - AIM: The aim of this study was to elucidate the relation between premorbid 
      personality traits and behavioral and psychological symptoms in dementia (BPSD) 
      in dementia with Lewy bodies (DLB) and Alzheimer's disease (AD) patients. 
      METHODS: Forty-one DLB patients and 98 AD patients were assessed for BPSD using 
      the Neuropsychiatric Inventory (NPI). Each patient's midlife personality traits 
      were rated by a family member using the NEO Five-Factor Inventory (NEO-FFI) 
      questionnaire. RESULTS: In multiple regression analyses for DLB patients, NPI 
      total score and anxiety were significantly associated with premorbid openness, 
      delusion with premorbid agreeableness, and agitation with premorbid 
      conscientiousness. In AD patients, depression was significantly associated with 
      premorbid neuroticism, and agitation, apathy, and irritability with premorbid 
      agreeableness. CONCLUSION: Premorbid personalities affected BPSD differently in 
      DLB and AD. Given the differences in the effects of premorbid personalities on 
      BPSD, additional studies are needed to develop interventions to reduce these 
      symptoms.
CI  - (c) 2017 The Authors. Psychiatry and Clinical Neurosciences (c) 2017 Japanese Society 
      of Psychiatry and Neurology.
FAU - Tabata, Kazuki
AU  - Tabata K
AD  - Department of Health Science, Asahikawa Medical University, Asahikawa, Japan.
AD  - Asahikawa Keisenkai Hospital, Asahikawa, Japan.
FAU - Saijo, Yasuaki
AU  - Saijo Y
AD  - Department of Health Science, Asahikawa Medical University, Asahikawa, Japan.
FAU - Morikawa, Fumiyoshi
AU  - Morikawa F
AD  - Asahikawa Keisenkai Hospital, Asahikawa, Japan.
FAU - Naoe, Juichiro
AU  - Naoe J
AD  - Asahikawa Keisenkai Hospital, Asahikawa, Japan.
FAU - Yoshioka, Eiji
AU  - Yoshioka E
AD  - Department of Health Science, Asahikawa Medical University, Asahikawa, Japan.
FAU - Kawanishi, Yasuyuki
AU  - Kawanishi Y
AD  - Department of Health Science, Asahikawa Medical University, Asahikawa, Japan.
FAU - Nakagi, Yoshihiko
AU  - Nakagi Y
AD  - Department of Health Science, Asahikawa Medical University, Asahikawa, Japan.
FAU - Yoshida, Takahiko
AU  - Yoshida T
AD  - Department of Health Science, Asahikawa Medical University, Asahikawa, Japan.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20170330
PL  - Australia
TA  - Psychiatry Clin Neurosci
JT  - Psychiatry and clinical neurosciences
JID - 9513551
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Alzheimer Disease/diagnosis/*psychology
MH  - Female
MH  - Humans
MH  - Lewy Body Disease/diagnosis/*psychology
MH  - Male
MH  - *Personality
MH  - Personality Inventory
OTO - NOTNLM
OT  - Alzheimer's disease
OT  - Neuropsychiatric Inventory
OT  - behavioral/psychological symptoms in dementia
OT  - dementia with Lewy bodies
OT  - premorbid personality
EDAT- 2017/02/09 06:00
MHDA- 2018/02/20 06:00
CRDT- 2017/02/09 06:00
PHST- 2016/08/29 00:00 [received]
PHST- 2017/01/10 00:00 [revised]
PHST- 2017/01/31 00:00 [accepted]
PHST- 2017/02/09 06:00 [pubmed]
PHST- 2018/02/20 06:00 [medline]
PHST- 2017/02/09 06:00 [entrez]
AID - 10.1111/pcn.12511 [doi]
PST - ppublish
SO  - Psychiatry Clin Neurosci. 2017 Jun;71(6):409-416. doi: 10.1111/pcn.12511. Epub 
      2017 Mar 30.